Nanotechnology for molecular imaging of atherosclerosis: current design and approaches

Atherosclerosis complications such as myocardial infarction or stroke is still one of the most critical causes of death worldwide. Advance and innovative diagnostic technologies are urgently required to discover an early stage of the disease, such as plaque instability and thrombosis. A combination...

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Main Authors: Maslizan, Mardhiah, Mat Azmi, Intan Diana, Mohamad Jaafar, Adila, Haris, Muhammad Salahuddin
Format: Article
Published: Akademia Baru Publishing 2021
Online Access:http://psasir.upm.edu.my/id/eprint/94328/
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author Maslizan, Mardhiah
Mat Azmi, Intan Diana
Mohamad Jaafar, Adila
Haris, Muhammad Salahuddin
author_facet Maslizan, Mardhiah
Mat Azmi, Intan Diana
Mohamad Jaafar, Adila
Haris, Muhammad Salahuddin
author_sort Maslizan, Mardhiah
building UPM Institutional Repository
collection Online Access
description Atherosclerosis complications such as myocardial infarction or stroke is still one of the most critical causes of death worldwide. Advance and innovative diagnostic technologies are urgently required to discover an early stage of the disease, such as plaque instability and thrombosis. A combination of molecular imaging probes based on well-designed nanomaterials with leading-edge imaging methods is currently concreting the direction for novel and distinctive approaches to examine the inflammatory growth in atherosclerosis. Over the past several decades, an exceptional understanding of the biological nature of atherosclerosis provides unique opportunities to better treat atherosclerotic disease with targeted imaging and nanomedicines. Consequently, tremendous development has been initiated in the nanotechnology application; the leading engineering tools working at molecular range, which is designed for diagnostic and therapeutic approach, called theranostic. This review underlying ideas involving the potential and development of molecular imaging technologies that had been invented for studying atherosclerosis. We envisage that many molecular imaging methods will become valuable assistants to the clinical management of targeted treatment in the atherosclerosis disease together with their challenges and future perspective in clinical translation.
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institution Universiti Putra Malaysia
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spelling upm-943282023-04-05T02:31:02Z http://psasir.upm.edu.my/id/eprint/94328/ Nanotechnology for molecular imaging of atherosclerosis: current design and approaches Maslizan, Mardhiah Mat Azmi, Intan Diana Mohamad Jaafar, Adila Haris, Muhammad Salahuddin Atherosclerosis complications such as myocardial infarction or stroke is still one of the most critical causes of death worldwide. Advance and innovative diagnostic technologies are urgently required to discover an early stage of the disease, such as plaque instability and thrombosis. A combination of molecular imaging probes based on well-designed nanomaterials with leading-edge imaging methods is currently concreting the direction for novel and distinctive approaches to examine the inflammatory growth in atherosclerosis. Over the past several decades, an exceptional understanding of the biological nature of atherosclerosis provides unique opportunities to better treat atherosclerotic disease with targeted imaging and nanomedicines. Consequently, tremendous development has been initiated in the nanotechnology application; the leading engineering tools working at molecular range, which is designed for diagnostic and therapeutic approach, called theranostic. This review underlying ideas involving the potential and development of molecular imaging technologies that had been invented for studying atherosclerosis. We envisage that many molecular imaging methods will become valuable assistants to the clinical management of targeted treatment in the atherosclerosis disease together with their challenges and future perspective in clinical translation. Akademia Baru Publishing 2021-04-01 Article PeerReviewed Maslizan, Mardhiah and Mat Azmi, Intan Diana and Mohamad Jaafar, Adila and Haris, Muhammad Salahuddin (2021) Nanotechnology for molecular imaging of atherosclerosis: current design and approaches. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 81 (2). 124 - 138. ISSN 2289-7879 https://www.akademiabaru.com/submit/index.php/arfmts/article/view/3622 10.37934/arfmts.81.2.124138
spellingShingle Maslizan, Mardhiah
Mat Azmi, Intan Diana
Mohamad Jaafar, Adila
Haris, Muhammad Salahuddin
Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title_full Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title_fullStr Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title_full_unstemmed Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title_short Nanotechnology for molecular imaging of atherosclerosis: current design and approaches
title_sort nanotechnology for molecular imaging of atherosclerosis: current design and approaches
url http://psasir.upm.edu.my/id/eprint/94328/
http://psasir.upm.edu.my/id/eprint/94328/
http://psasir.upm.edu.my/id/eprint/94328/