K-ras peptide mimotope induces antigen specific Th1 and B-cell immune responses against G12A-mutated K-Ras antigen in balb/c mice

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K-ras peptide mimotope induces antigen specific Th1 and B-cell immune responses against G12A-mutated K-Ras antigen in balb/c mice

KRAS G12A somatic point mutation in adenocarcinomas is categorized clinically as ineligibility criteria for anti-epidermal growth factor receptor (EGFR) monoclonal antibody therapies. In this study, a modified G12A-K-ras epitope (139A) with sequence-specific modifications to improve immunogenicity w...

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Bibliographic Details
Main Authors:	Siak, Pui Yan, Wong, Kuan Yee, Song, Adelene Ai Lian, Abdul Rahim, Raha, Lian, Lionel Aun In
Format:	Article
Published:	Multidisciplinary Digital Publishing Institute 2021
Online Access:	http://psasir.upm.edu.my/id/eprint/93999/

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