Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present...
| Main Authors: | , , , , , |
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| Format: | Article |
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Elsevier
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/93544/ |
| _version_ | 1848861866817748992 |
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| author | Md Noh, Mohamad Syafeeq Faeez Rajadurai, Naveen Hassan, Thajunnisa Alias, Mardziah Robert, Penafort Chong, Yip Boon |
| author_facet | Md Noh, Mohamad Syafeeq Faeez Rajadurai, Naveen Hassan, Thajunnisa Alias, Mardziah Robert, Penafort Chong, Yip Boon |
| author_sort | Md Noh, Mohamad Syafeeq Faeez |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present a young male presenting with acute back pain, initially suspicious of malignancy, with an eventual diagnosis of vertebral sarcoidosis; with sacrum, pelvic bone, and cutaneous involvement (Darier-Roussy disease), as well as associated mediastinal and abdominal lymphadenopathy. Following the diagnosis of vertebral sarcoidosis with associated Darier-Roussy disease, the patient was offered treatment but was not keen at the time of diagnosis. An outpatient appointment to re-discuss treatment options was given, should it be pursued. Conclusion: Vertebral sarcoidosis with associated Darier-Roussy disease is an extremely rare clinical entity, with multiple differential diagnoses. Pathological examination is confirmatory and should be pursued for accurate diagnosis and treatment. |
| first_indexed | 2025-11-15T13:07:56Z |
| format | Article |
| id | upm-93544 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:07:56Z |
| publishDate | 2021 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-935442023-01-13T03:34:38Z http://psasir.upm.edu.my/id/eprint/93544/ Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain Md Noh, Mohamad Syafeeq Faeez Rajadurai, Naveen Hassan, Thajunnisa Alias, Mardziah Robert, Penafort Chong, Yip Boon Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present a young male presenting with acute back pain, initially suspicious of malignancy, with an eventual diagnosis of vertebral sarcoidosis; with sacrum, pelvic bone, and cutaneous involvement (Darier-Roussy disease), as well as associated mediastinal and abdominal lymphadenopathy. Following the diagnosis of vertebral sarcoidosis with associated Darier-Roussy disease, the patient was offered treatment but was not keen at the time of diagnosis. An outpatient appointment to re-discuss treatment options was given, should it be pursued. Conclusion: Vertebral sarcoidosis with associated Darier-Roussy disease is an extremely rare clinical entity, with multiple differential diagnoses. Pathological examination is confirmatory and should be pursued for accurate diagnosis and treatment. Elsevier 2021-12 Article PeerReviewed Md Noh, Mohamad Syafeeq Faeez and Rajadurai, Naveen and Hassan, Thajunnisa and Alias, Mardziah and Robert, Penafort and Chong, Yip Boon (2021) Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain. Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, 26. art. no. 101330. pp. 1-6. ISSN 2214-7519 https://www.sciencedirect.com/science/article/pii/S2214751921002425 10.1016/j.inat.2021.101330 |
| spellingShingle | Md Noh, Mohamad Syafeeq Faeez Rajadurai, Naveen Hassan, Thajunnisa Alias, Mardziah Robert, Penafort Chong, Yip Boon Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title | Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title_full | Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title_fullStr | Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title_full_unstemmed | Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title_short | Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain |
| title_sort | vertebral sarcoidosis with associated darier-roussy disease manifesting as acute back pain |
| url | http://psasir.upm.edu.my/id/eprint/93544/ http://psasir.upm.edu.my/id/eprint/93544/ http://psasir.upm.edu.my/id/eprint/93544/ |