Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities
The phytochemical study on Glycosmis crassifolia (limau hutan) and G. chlorosperma (Rutaceae) involves extraction and separation by using various chromatographic methods, structural determination by spectroscopic techniques such as IR, NMR including 2D-NMR and MS. The structure of the compounds...
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| Format: | Thesis |
| Language: | English English |
| Published: |
2001
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| Online Access: | http://psasir.upm.edu.my/id/eprint/9284/ http://psasir.upm.edu.my/id/eprint/9284/2/FSAS_2001_30_A.pdf |
| _version_ | 1848841103484125184 |
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| author | Nafiah, Mohd Azlan |
| author_facet | Nafiah, Mohd Azlan |
| author_sort | Nafiah, Mohd Azlan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The phytochemical study on Glycosmis crassifolia (limau hutan) and G.
chlorosperma (Rutaceae) involves extraction and separation by using various
chromatographic methods, structural determination by spectroscopic techniques
such as IR, NMR including 2D-NMR and MS. The structure of the compounds
were elucidated by comparison with the previous works. Isolation work on roots
of G. crassifolia yielded maculocidine (44). From the leaves, two more
compounds were isolated and the structure elucidated. One of them was identified
as a new alkaloid, glycofuranoxine (45) and the other one was stigmata-3,5,22-trien-3-01 (46). Further study on the twigs of the same plant afforded two known
compounds including ergosta-4,6-dien-3-01 (47) and stigmata-5-en-3-01 (48).
Detail study on the leaves extract of Glycosmis chlorosperma yielded two
compounds. One of them was identified as a new compound, 5-hydroxy-7,4'dimethoxy-
8-(-3"-methylbut-2"-enyl)f1avanone (49) and the other one was known
as dambullin (50).
Crude extract from various plant were screened for antifungal activity
using poison food method against Sclerotium rolfsii. However, the petroleumether,
chloroform and methanol extract of the roots, leaves and twigs of the plant
failed to show any activity in inhibition of mycelial growth and sclerotial
germination. |
| first_indexed | 2025-11-15T07:37:55Z |
| format | Thesis |
| id | upm-9284 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:37:55Z |
| publishDate | 2001 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-92842013-09-30T00:38:33Z http://psasir.upm.edu.my/id/eprint/9284/ Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities Nafiah, Mohd Azlan The phytochemical study on Glycosmis crassifolia (limau hutan) and G. chlorosperma (Rutaceae) involves extraction and separation by using various chromatographic methods, structural determination by spectroscopic techniques such as IR, NMR including 2D-NMR and MS. The structure of the compounds were elucidated by comparison with the previous works. Isolation work on roots of G. crassifolia yielded maculocidine (44). From the leaves, two more compounds were isolated and the structure elucidated. One of them was identified as a new alkaloid, glycofuranoxine (45) and the other one was stigmata-3,5,22-trien-3-01 (46). Further study on the twigs of the same plant afforded two known compounds including ergosta-4,6-dien-3-01 (47) and stigmata-5-en-3-01 (48). Detail study on the leaves extract of Glycosmis chlorosperma yielded two compounds. One of them was identified as a new compound, 5-hydroxy-7,4'dimethoxy- 8-(-3"-methylbut-2"-enyl)f1avanone (49) and the other one was known as dambullin (50). Crude extract from various plant were screened for antifungal activity using poison food method against Sclerotium rolfsii. However, the petroleumether, chloroform and methanol extract of the roots, leaves and twigs of the plant failed to show any activity in inhibition of mycelial growth and sclerotial germination. 2001-09 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/9284/2/FSAS_2001_30_A.pdf Nafiah, Mohd Azlan (2001) Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities. Masters thesis, Universiti Putra Malaysia. Glycosmis Chemical elements - Spectra English |
| spellingShingle | Glycosmis Chemical elements - Spectra Nafiah, Mohd Azlan Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title | Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title_full | Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title_fullStr | Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title_full_unstemmed | Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title_short | Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities |
| title_sort | chemical constituents of glycosmis crassifolia and g. chlorosperma (rutaceae) and their biological activities |
| topic | Glycosmis Chemical elements - Spectra |
| url | http://psasir.upm.edu.my/id/eprint/9284/ http://psasir.upm.edu.my/id/eprint/9284/2/FSAS_2001_30_A.pdf |