A rare case of factor Xii deficiency in a pregnant woman
Factor XII deficiency, also known as the Hageman factor, is a rare disorder that has not been associated with any adverse outcomes. It is an interesting blood disorder whereby in the state of deficiency, it causes prolongation activated partial thromboplastin time (aPTT) which is correctable with mi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/90401/ http://psasir.upm.edu.my/id/eprint/90401/1/2021062816130846_MJMHS_0303.pdf |
| _version_ | 1848861057237385216 |
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| author | Arimuthu, Durga Arinandini Lim, Christopher Thiam Seong |
| author_facet | Arimuthu, Durga Arinandini Lim, Christopher Thiam Seong |
| author_sort | Arimuthu, Durga Arinandini |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Factor XII deficiency, also known as the Hageman factor, is a rare disorder that has not been associated with any adverse outcomes. It is an interesting blood disorder whereby in the state of deficiency, it causes prolongation activated partial thromboplastin time (aPTT) which is correctable with mixing test. Although there have been case reports that have mentioned events of thrombosis and bleeding, however, no clear causal relationship has been established. Evidence for adverse events occurring in patients with Factor XII deficiency is sparse. We report here a case of a lady with a history of miscarriages who was incidentally found to have Factor XII deficiency during a routine workup for prolonged aPTT. |
| first_indexed | 2025-11-15T12:55:04Z |
| format | Article |
| id | upm-90401 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:55:04Z |
| publishDate | 2021 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-904012021-09-10T01:44:33Z http://psasir.upm.edu.my/id/eprint/90401/ A rare case of factor Xii deficiency in a pregnant woman Arimuthu, Durga Arinandini Lim, Christopher Thiam Seong Factor XII deficiency, also known as the Hageman factor, is a rare disorder that has not been associated with any adverse outcomes. It is an interesting blood disorder whereby in the state of deficiency, it causes prolongation activated partial thromboplastin time (aPTT) which is correctable with mixing test. Although there have been case reports that have mentioned events of thrombosis and bleeding, however, no clear causal relationship has been established. Evidence for adverse events occurring in patients with Factor XII deficiency is sparse. We report here a case of a lady with a history of miscarriages who was incidentally found to have Factor XII deficiency during a routine workup for prolonged aPTT. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2021-07 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/90401/1/2021062816130846_MJMHS_0303.pdf Arimuthu, Durga Arinandini and Lim, Christopher Thiam Seong (2021) A rare case of factor Xii deficiency in a pregnant woman. Malaysian Journal of Medicine and Health Sciences, 17 (3). pp. 319-321. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2021062816130846_MJMHS_0303.pdf |
| spellingShingle | Arimuthu, Durga Arinandini Lim, Christopher Thiam Seong A rare case of factor Xii deficiency in a pregnant woman |
| title | A rare case of factor Xii deficiency in a pregnant woman |
| title_full | A rare case of factor Xii deficiency in a pregnant woman |
| title_fullStr | A rare case of factor Xii deficiency in a pregnant woman |
| title_full_unstemmed | A rare case of factor Xii deficiency in a pregnant woman |
| title_short | A rare case of factor Xii deficiency in a pregnant woman |
| title_sort | rare case of factor xii deficiency in a pregnant woman |
| url | http://psasir.upm.edu.my/id/eprint/90401/ http://psasir.upm.edu.my/id/eprint/90401/ http://psasir.upm.edu.my/id/eprint/90401/1/2021062816130846_MJMHS_0303.pdf |