Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review
Recent improvement in the treatment and management of α-thalassaemia has enabled patients to live longer and have better quality of life, thus revealing other complications related to the disorder mainly due to the effects of chronic ineffective erythropoiesis and iron overload. We review the renal...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/90195/ http://psasir.upm.edu.my/id/eprint/90195/1/14upm.pdf |
| _version_ | 1848861001312632832 |
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| author | Nor Aziz Hashim, Nurul Aiman Farhana Lai, Mei I. |
| author_facet | Nor Aziz Hashim, Nurul Aiman Farhana Lai, Mei I. |
| author_sort | Nor Aziz Hashim, Nurul Aiman Farhana |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Recent improvement in the treatment and management of α-thalassaemia has enabled patients to live longer and have better quality of life, thus revealing other complications related to the disorder mainly due to the effects of chronic ineffective erythropoiesis and iron overload. We review the renal dysfunction seen in α-thalassaemia as it has been reported (published and personal communication) that the complications presented are more severe than those found in β-thalassaemia patients of similar severity clinically. This review aims to shed light on emerging complications that are currently faced by α-thalassaemia patients as they progress further in life. |
| first_indexed | 2025-11-15T12:54:11Z |
| format | Article |
| id | upm-90195 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:54:11Z |
| publishDate | 2020 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-901952021-09-09T11:19:52Z http://psasir.upm.edu.my/id/eprint/90195/ Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review Nor Aziz Hashim, Nurul Aiman Farhana Lai, Mei I. Recent improvement in the treatment and management of α-thalassaemia has enabled patients to live longer and have better quality of life, thus revealing other complications related to the disorder mainly due to the effects of chronic ineffective erythropoiesis and iron overload. We review the renal dysfunction seen in α-thalassaemia as it has been reported (published and personal communication) that the complications presented are more severe than those found in β-thalassaemia patients of similar severity clinically. This review aims to shed light on emerging complications that are currently faced by α-thalassaemia patients as they progress further in life. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2020-11 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/90195/1/14upm.pdf Nor Aziz Hashim, Nurul Aiman Farhana and Lai, Mei I. (2020) Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review. Malaysian Journal of Medicine and Health Sciences, 16 (suppl. 9). pp. 89-96. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2020110611205014_2020_0478.pdf |
| spellingShingle | Nor Aziz Hashim, Nurul Aiman Farhana Lai, Mei I. Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title | Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title_full | Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title_fullStr | Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title_full_unstemmed | Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title_short | Elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| title_sort | elucidating the possible mechanism of renal dysfunction in alpha thalassaemia: a review |
| url | http://psasir.upm.edu.my/id/eprint/90195/ http://psasir.upm.edu.my/id/eprint/90195/ http://psasir.upm.edu.my/id/eprint/90195/1/14upm.pdf |