Expression of gamma secretase and notch signalling pathway in TS1CJE mouse model of down syndrome
Many medical complications such as hypotonia, congenital heart defects, intellectual disability and cognitive impairments are seen in Down syndrome (DS) individuals. Studies have shown that an increased glial-to-neuron ratio contributes to the intellectual disability of DS individuals. This neuro...
| Main Author: | Md Yusof, Hadri Hadi |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2017
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/90075/ http://psasir.upm.edu.my/id/eprint/90075/3/FPSK%28M%29%202019%2036%20%20UPM%20ir.pdf |
Similar Items
Histological and molecular characterisation of hypotonia in adult Ts1Cje mouse model for down syndrome
by: Bala, Usman
Published: (2016)
by: Bala, Usman
Published: (2016)
Transcriptomic and protein expression analyses of skeletal muscles isolated from Ts1cje mouse model for Down syndrome
by: Leong, Melody Pui Yee
Published: (2017)
by: Leong, Melody Pui Yee
Published: (2017)
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)
by: Lim, Chai Ling
Published: (2017)
Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome
by: Md Yusof, Hadri Hadi, et al.
Published: (2019)
by: Md Yusof, Hadri Hadi, et al.
Published: (2019)
Metabolic profiling of neurospheres derived from embryonic cerebral cortex Ts1Cje mouse model for down syndrome
by: Mohamed Seth, Eryse Amira
Published: (2019)
by: Mohamed Seth, Eryse Amira
Published: (2019)
Identification of disrupted molecular networks involved in brain maturation and function in the TS1CJE mouse model of down syndrome
by: Tan, Kai Leng
Published: (2016)
by: Tan, Kai Leng
Published: (2016)
The triple challenges associated with age-related comorbidities in Down syndrome
by: Glasson, E., et al.
Published: (2013)
by: Glasson, E., et al.
Published: (2013)
Ts1Cje mouse model for Down syndrome research
by: Ling, King Hwa
Published: (2015)
by: Ling, King Hwa
Published: (2015)
Gene and protein expression profiles of JAK-STAT signalling pathway in the developing brain of the Ts1Cje down syndrome mouse model
by: Lee, Han Chung, et al.
Published: (2019)
by: Lee, Han Chung, et al.
Published: (2019)
The role of JAK-STAT signalling in the developing brain of Ts1Cje mouse model for Down syndrome
by: Lee, Han Chung, et al.
Published: (2015)
by: Lee, Han Chung, et al.
Published: (2015)
Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2014)
by: Tan, Kai Leng, et al.
Published: (2014)
An evaluation of tablet-based apps for maths learning in young children with Down's Syndrome
by: Allison, Kate
Published: (2019)
by: Allison, Kate
Published: (2019)
Prenatal screening for Down Syndrome in Australia: costs and benefits of current and novel screening strategies
by: O'Leary, Peter, et al.
Published: (2013)
by: O'Leary, Peter, et al.
Published: (2013)
Lebih kromosom punca SD
by: Berita Harian ,
Published: (2011)
by: Berita Harian ,
Published: (2011)
Impairments in the Visual Processing of Global Biological Motion Cues in Down Syndrome
by: Riddell, Hugh, et al.
Published: (2017)
by: Riddell, Hugh, et al.
Published: (2017)
Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
by: Hewitt, Chelsee Ann, et al.
Published: (2010)
by: Hewitt, Chelsee Ann, et al.
Published: (2010)
Expression profiling of genes involved in the development and function of skeletal muscles in Ts1Cje mouse model of down syndrome
by: Cheah, Pike See, et al.
Published: (2018)
by: Cheah, Pike See, et al.
Published: (2018)
The expression profile of miR-3099 during neural development of Ts1Cje mouse model of down syndrome
by: Zainal Abidin, Shahidee, et al.
Published: (2021)
by: Zainal Abidin, Shahidee, et al.
Published: (2021)
Overexpression of interferon alpha or beta receptors in the brain of adult Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2015)
by: Tan, Kai Leng, et al.
Published: (2015)
Targeted differential gene expression profiling of skeletal muscles isolated from Ts1Cje mouse model for Down syndrome
by: Leong, Melody Pui Yee, et al.
Published: (2015)
by: Leong, Melody Pui Yee, et al.
Published: (2015)
The identification of disrupted molecular networks involved in brain maturation and function in the Ts1Cje mouse model of down syndrome.
by: Cheah, P. S.
by: Cheah, P. S.
Perturbed metabolic profiles associated with muscle weakness seen in adult Ts1Cje mouse model of Down syndrome
by: Lim, Chai Ling, et al.
Published: (2019)
by: Lim, Chai Ling, et al.
Published: (2019)
Kesan intervensi imbangan dan kawalan postur terhadap perkembangan motor kasar kanak-kanak sindrom down di Wilayah Persekutuan Kuala Lumpur
by: Teng, Siew Lian
Published: (2012)
by: Teng, Siew Lian
Published: (2012)
Disrupted interferon-related molecular networks and the over-expressed Ifnar1 in the brain of adult Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2016)
by: Tan, Kai Leng, et al.
Published: (2016)
Ts1Cje mouse model for Down syndrome exhibits motor function deficit; the potential role of MRFS and peripheral nervous system
by: Bala, Usman, et al.
Published: (2015)
by: Bala, Usman, et al.
Published: (2015)
Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model
by: Bala, Usman, et al.
Published: (2018)
by: Bala, Usman, et al.
Published: (2018)
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
by: Ling, King Hwa, et al.
Published: (2014)
by: Ling, King Hwa, et al.
Published: (2014)
Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome
by: Chong, Teik Lim, et al.
Published: (2024)
by: Chong, Teik Lim, et al.
Published: (2024)
Testing questions
by: O'Leary, Peter
Published: (2013)
by: O'Leary, Peter
Published: (2013)
Lithium restores nuclear REST and Mitigates oxidative stress in down syndrome iPSC-Derived neurons
by: Lam, Xin-Jieh, et al.
Published: (2025)
by: Lam, Xin-Jieh, et al.
Published: (2025)
Effects of gamma-secretase inhibitor GSI-34 on bladder cancer cell viability, migration and notch-associated gene expression levels
by: Roslan, Nadzatul Nabila
Published: (2017)
by: Roslan, Nadzatul Nabila
Published: (2017)
Development and Testing of Down-the-Hole Deployabe X-Ray Florescence Spectrometer
by: Carter, Geoffrey, et al.
Published: (2010)
by: Carter, Geoffrey, et al.
Published: (2010)
Reversible splenial lesion syndrome in neuroleptic malignant syndrome.
by: Al-Edrus, Sharifah Aishah, et al.
Published: (2009)
by: Al-Edrus, Sharifah Aishah, et al.
Published: (2009)
The structure and function of Alzheimer's gamma secretase enzyme complex
by: Krishnaswamy, S., et al.
Published: (2009)
by: Krishnaswamy, S., et al.
Published: (2009)
Efficient production of a mature and functional gamma secretase protease
by: Khan, I., et al.
Published: (2018)
by: Khan, I., et al.
Published: (2018)
Exploring function and effective connectivity of the motor cortex and its role in Tourette syndrome
by: Pépés, Sophia
Published: (2017)
by: Pépés, Sophia
Published: (2017)
Mercury-Induced Nephrotic Syndrome: A Correlation between Pathological Changes and Serum and Urine Biochemistry Parameters in Rats
by: Ibrahim, Suhaidah
Published: (1998)
by: Ibrahim, Suhaidah
Published: (1998)
Assessment of Carpal Tunnel Syndrome risk among designers performing digital design activities
by: Mohd Juzad, Kodsiah
Published: (2023)
by: Mohd Juzad, Kodsiah
Published: (2023)
Prevalence of metabolic syndrome and associated factors in Yobe state provence of Nigeria
by: Likita, Musa Audu
Published: (2014)
by: Likita, Musa Audu
Published: (2014)
Expression analysis of notch signaling pathway molecules in SHED cultured in keratinocyte growth medium
by: Mohd Taha, Siti Aisyah, et al.
Published: (2015)
by: Mohd Taha, Siti Aisyah, et al.
Published: (2015)
Similar Items
-
Histological and molecular characterisation of hypotonia in adult Ts1Cje mouse model for down syndrome
by: Bala, Usman
Published: (2016) -
Transcriptomic and protein expression analyses of skeletal muscles isolated from Ts1cje mouse model for Down syndrome
by: Leong, Melody Pui Yee
Published: (2017) -
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017) -
Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome
by: Md Yusof, Hadri Hadi, et al.
Published: (2019) -
Metabolic profiling of neurospheres derived from embryonic cerebral cortex Ts1Cje mouse model for down syndrome
by: Mohamed Seth, Eryse Amira
Published: (2019)