In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp
Curcuma mangga belongs to the family Zingibereae locally known as “mango ginger” or “manggo turmeric”. Medicinally, the rhizomes of Curcuma mangga are used for treatment of stomach and chest pains, fever, stomach ulcer and general weakness. It is also used in postpartum treatment, particularly to he...
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| Format: | Article |
| Language: | English |
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Diva Enterprises
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/89330/ http://psasir.upm.edu.my/id/eprint/89330/1/MANGGA.pdf |
| _version_ | 1848860827718778880 |
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| author | Mohammad, Noor Halimatul Saadiah Mohd Aspollah, Sukari Ismail, Intan Safinar Bustamam, Abdul Ahmad |
| author_facet | Mohammad, Noor Halimatul Saadiah Mohd Aspollah, Sukari Ismail, Intan Safinar Bustamam, Abdul Ahmad |
| author_sort | Mohammad, Noor Halimatul Saadiah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Curcuma mangga belongs to the family Zingibereae locally known as “mango ginger” or “manggo turmeric”. Medicinally, the rhizomes of Curcuma mangga are used for treatment of stomach and chest pains, fever, stomach ulcer and general weakness. It is also used in postpartum treatment, particularly to help in the healing of the womb. The various medicinal purpose of this species inspired further phytochemical studies and potential biological activities. Phytochemical studies reported the isolation of six compounds identifies as curcumin (1), demethoxycurcumin (2), curcumol (3), curdione (4), zederone (5) and β-Sitosterol (6). Curcumol (3), curdione (4) and zederone (5) are reported to be first isolated from this species. Crude extracts and isolated constituents possessed potential cytotoxic activities against five human cancerous cell lines; promyelocytic leukemia (HL-60), breast cancer (MCF-7), colonic cancer (HT-29), cervical cancer (HeLa) and T-lymphoblastic (CEM-SS). Promising antioxidant activities and remarkable antimicrobial properties are recorded against Methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtillis and Pseudomonas aeruginosa. |
| first_indexed | 2025-11-15T12:51:25Z |
| format | Article |
| id | upm-89330 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:51:25Z |
| publishDate | 2020 |
| publisher | Diva Enterprises |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-893302021-09-17T22:06:45Z http://psasir.upm.edu.my/id/eprint/89330/ In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp Mohammad, Noor Halimatul Saadiah Mohd Aspollah, Sukari Ismail, Intan Safinar Bustamam, Abdul Ahmad Curcuma mangga belongs to the family Zingibereae locally known as “mango ginger” or “manggo turmeric”. Medicinally, the rhizomes of Curcuma mangga are used for treatment of stomach and chest pains, fever, stomach ulcer and general weakness. It is also used in postpartum treatment, particularly to help in the healing of the womb. The various medicinal purpose of this species inspired further phytochemical studies and potential biological activities. Phytochemical studies reported the isolation of six compounds identifies as curcumin (1), demethoxycurcumin (2), curcumol (3), curdione (4), zederone (5) and β-Sitosterol (6). Curcumol (3), curdione (4) and zederone (5) are reported to be first isolated from this species. Crude extracts and isolated constituents possessed potential cytotoxic activities against five human cancerous cell lines; promyelocytic leukemia (HL-60), breast cancer (MCF-7), colonic cancer (HT-29), cervical cancer (HeLa) and T-lymphoblastic (CEM-SS). Promising antioxidant activities and remarkable antimicrobial properties are recorded against Methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtillis and Pseudomonas aeruginosa. Diva Enterprises 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89330/1/MANGGA.pdf Mohammad, Noor Halimatul Saadiah and Mohd Aspollah, Sukari and Ismail, Intan Safinar and Bustamam, Abdul Ahmad (2020) In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp. International Journal of Medical Toxicology and Legal Medicine, 23 (1 and 2). 251 - 256. ISSN 0972-0448; ESSN: 0974-4614 https://www.indianjournals.com/ijor.aspx?target=ijor:ijmtlm&volume=23&issue=1and2&article=036 10.5958/0974-4614.2020.00036.4 |
| spellingShingle | Mohammad, Noor Halimatul Saadiah Mohd Aspollah, Sukari Ismail, Intan Safinar Bustamam, Abdul Ahmad In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title | In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title_full | In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title_fullStr | In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title_full_unstemmed | In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title_short | In vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| title_sort | in vitro cytotoxic, radical scavenging and antimicrobial activities of curcuma mangga valeton and van zijp |
| url | http://psasir.upm.edu.my/id/eprint/89330/ http://psasir.upm.edu.my/id/eprint/89330/ http://psasir.upm.edu.my/id/eprint/89330/ http://psasir.upm.edu.my/id/eprint/89330/1/MANGGA.pdf |