Herbal medication triggering lupus nephritis - a case report
Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases in...
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| Format: | Article |
| Language: | English |
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BioMed Central
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/89171/ http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf |
| _version_ | 1848860788815560704 |
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| author | Abdul Rashid, Anna Misya’il Abd Ghani, Fauzah Inche Mat, Liyana Najwa Thiam, Christopher Seong Lim |
| author_facet | Abdul Rashid, Anna Misya’il Abd Ghani, Fauzah Inche Mat, Liyana Najwa Thiam, Christopher Seong Lim |
| author_sort | Abdul Rashid, Anna Misya’il |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases including Systemic Lupus Erythematosus (SLE). Some even lay claims to be able to cure SLE. Although they are not without side effects, these medications are still preferred due to their widespread availability and affordability, compared to modern medications. However, to date, there have been no reported cases in which these traditional medications can trigger a lupus-like reaction, moreover one
involving the kidneys. Case presentation: We report a patient who developed overt lupus nephritis after consuming a course of herbal
supplement. Her renal status did not improve upon cessation of the offending drug, and she required immunosuppressive therapy. After one cycle of IV cyclophosphamide, we managed to get the patient into remission - she is now on tapering doses of steroids.
Conclusion: We wish to highlight the possibility of consumption of herbal medication and the emergence of drug-induced lupus nephritis. A thorough anamnesis and high index of suspicion of drug-induced lupus nephritis is warranted when a patient on supplements presents with urinary abnormalities. |
| first_indexed | 2025-11-15T12:50:48Z |
| format | Article |
| id | upm-89171 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:50:48Z |
| publishDate | 2020 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-891712021-09-03T22:21:14Z http://psasir.upm.edu.my/id/eprint/89171/ Herbal medication triggering lupus nephritis - a case report Abdul Rashid, Anna Misya’il Abd Ghani, Fauzah Inche Mat, Liyana Najwa Thiam, Christopher Seong Lim Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases including Systemic Lupus Erythematosus (SLE). Some even lay claims to be able to cure SLE. Although they are not without side effects, these medications are still preferred due to their widespread availability and affordability, compared to modern medications. However, to date, there have been no reported cases in which these traditional medications can trigger a lupus-like reaction, moreover one involving the kidneys. Case presentation: We report a patient who developed overt lupus nephritis after consuming a course of herbal supplement. Her renal status did not improve upon cessation of the offending drug, and she required immunosuppressive therapy. After one cycle of IV cyclophosphamide, we managed to get the patient into remission - she is now on tapering doses of steroids. Conclusion: We wish to highlight the possibility of consumption of herbal medication and the emergence of drug-induced lupus nephritis. A thorough anamnesis and high index of suspicion of drug-induced lupus nephritis is warranted when a patient on supplements presents with urinary abnormalities. BioMed Central 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf Abdul Rashid, Anna Misya’il and Abd Ghani, Fauzah and Inche Mat, Liyana Najwa and Thiam, Christopher Seong Lim (2020) Herbal medication triggering lupus nephritis - a case report. BMC Complementary Medicine and Therapies, 20 (1). art. no. 163. pp. 1-6. ISSN 2662-7671 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268707 10.1186/s12906-020-02971-y |
| spellingShingle | Abdul Rashid, Anna Misya’il Abd Ghani, Fauzah Inche Mat, Liyana Najwa Thiam, Christopher Seong Lim Herbal medication triggering lupus nephritis - a case report |
| title | Herbal medication triggering lupus nephritis - a case report |
| title_full | Herbal medication triggering lupus nephritis - a case report |
| title_fullStr | Herbal medication triggering lupus nephritis - a case report |
| title_full_unstemmed | Herbal medication triggering lupus nephritis - a case report |
| title_short | Herbal medication triggering lupus nephritis - a case report |
| title_sort | herbal medication triggering lupus nephritis - a case report |
| url | http://psasir.upm.edu.my/id/eprint/89171/ http://psasir.upm.edu.my/id/eprint/89171/ http://psasir.upm.edu.my/id/eprint/89171/ http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf |