Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case
This study investigated the impact of paravalvular leakage (PVL) in relation to the different valve openings of the transcatheter aortic valve implantation (TAVI) valve using the fluid structure interaction (FSI) approach. Limited studies were found on the subject of FSI with regards to TAVI-PVL con...
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| Format: | Article |
| Language: | English |
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Hindawi
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/89047/ http://psasir.upm.edu.my/id/eprint/89047/1/FLUID.pdf |
| _version_ | 1848860760506105856 |
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| author | Basri, Adi Azriff Zuber, Mohammad Basri, Ernnie Illyani Zakaria, Muhammad S. Aziz, Ahmad F. A. Tamagawa, Masaaki Ahmad, Kamarul Arifin |
| author_facet | Basri, Adi Azriff Zuber, Mohammad Basri, Ernnie Illyani Zakaria, Muhammad S. Aziz, Ahmad F. A. Tamagawa, Masaaki Ahmad, Kamarul Arifin |
| author_sort | Basri, Adi Azriff |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study investigated the impact of paravalvular leakage (PVL) in relation to the different valve openings of the transcatheter aortic valve implantation (TAVI) valve using the fluid structure interaction (FSI) approach. Limited studies were found on the subject of FSI with regards to TAVI-PVL condition, which involves both fluid and structural responses in coupling interaction. Hence, further FSI simulation with the two-way coupling method is implemented to investigate the effects of hemodynamics blood flow along the patient-specific aorta model subjected to the interrelationship between PVL and the different valve openings using the established FSI software ANSYS 16.1. A 3D patient-specific aorta model is constructed using MIMICS software. The TAVI valve identical to Edward SAPIEN XT 26 (Edwards Lifesciences, Irvine, California), at different Geometrical Orifice Areas (GOAs), is implanted into the patient’s aortic annulus. The leaflet opening of the TAVI valve is drawn according to severity of GOA opening represented in terms of 100%, 80%, 60%, and 40% opening, respectively. The result proved that the smallest percentage of GOA opening produced the highest possibility of PVL, increased the recirculatory flow proximally to the inner wall of the ascending aorta, and produced lower backflow velocity streamlines through the side area of PVL region. Overall, 40% GOA produced 89.17% increment of maximum velocity magnitude, 19.97% of pressure drop, 65.70% of maximum WSS magnitude, and a decrement of 33.62% total displacement magnitude with respect to the 100% GOA. |
| first_indexed | 2025-11-15T12:50:21Z |
| format | Article |
| id | upm-89047 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:50:21Z |
| publishDate | 2020 |
| publisher | Hindawi |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-890472021-09-21T22:59:42Z http://psasir.upm.edu.my/id/eprint/89047/ Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case Basri, Adi Azriff Zuber, Mohammad Basri, Ernnie Illyani Zakaria, Muhammad S. Aziz, Ahmad F. A. Tamagawa, Masaaki Ahmad, Kamarul Arifin This study investigated the impact of paravalvular leakage (PVL) in relation to the different valve openings of the transcatheter aortic valve implantation (TAVI) valve using the fluid structure interaction (FSI) approach. Limited studies were found on the subject of FSI with regards to TAVI-PVL condition, which involves both fluid and structural responses in coupling interaction. Hence, further FSI simulation with the two-way coupling method is implemented to investigate the effects of hemodynamics blood flow along the patient-specific aorta model subjected to the interrelationship between PVL and the different valve openings using the established FSI software ANSYS 16.1. A 3D patient-specific aorta model is constructed using MIMICS software. The TAVI valve identical to Edward SAPIEN XT 26 (Edwards Lifesciences, Irvine, California), at different Geometrical Orifice Areas (GOAs), is implanted into the patient’s aortic annulus. The leaflet opening of the TAVI valve is drawn according to severity of GOA opening represented in terms of 100%, 80%, 60%, and 40% opening, respectively. The result proved that the smallest percentage of GOA opening produced the highest possibility of PVL, increased the recirculatory flow proximally to the inner wall of the ascending aorta, and produced lower backflow velocity streamlines through the side area of PVL region. Overall, 40% GOA produced 89.17% increment of maximum velocity magnitude, 19.97% of pressure drop, 65.70% of maximum WSS magnitude, and a decrement of 33.62% total displacement magnitude with respect to the 100% GOA. Hindawi 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89047/1/FLUID.pdf Basri, Adi Azriff and Zuber, Mohammad and Basri, Ernnie Illyani and Zakaria, Muhammad S. and Aziz, Ahmad F. A. and Tamagawa, Masaaki and Ahmad, Kamarul Arifin (2020) Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case. Computational and Mathematical Methods in Medicine, 2020. art. no. 9163085. pp. 1-22. ISSN 1748-670X; ESSN: 1748-6718 https://www.hindawi.com/journals/cmmm/2020/9163085/ 10.1155/2020/9163085 |
| spellingShingle | Basri, Adi Azriff Zuber, Mohammad Basri, Ernnie Illyani Zakaria, Muhammad S. Aziz, Ahmad F. A. Tamagawa, Masaaki Ahmad, Kamarul Arifin Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title | Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title_full | Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title_fullStr | Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title_full_unstemmed | Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title_short | Fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| title_sort | fluid structure interaction on paravalvular leakage of transcatheter aortic valve implantation related to aortic stenosis: a patient-specific case |
| url | http://psasir.upm.edu.my/id/eprint/89047/ http://psasir.upm.edu.my/id/eprint/89047/ http://psasir.upm.edu.my/id/eprint/89047/ http://psasir.upm.edu.my/id/eprint/89047/1/FLUID.pdf |