Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid

Thermostable T1 lipase from Geobacillus zalihae strain was utilized in esterification of various sugars with fatty acids to form fatty acid sugar esters. Fatty acid sugar esters (FASE) are an important class of non-ionic surfactant which possesses good emulsifying, stabilizing and conditioning prope...

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Main Authors: Abdulmalek, Emilia, Mohd Saupi, Hanim Salami, Zulkefli, Syarilaida, Raja Abd Rahman, Raja Noor Zaliha, Abdul Rahman, Mohd Basyaruddin
Format: Article
Language:English
Published: Faculty of Science and Technology, Universiti Kebangsaan Malaysia 2020
Online Access:http://psasir.upm.edu.my/id/eprint/88836/
http://psasir.upm.edu.my/id/eprint/88836/1/ABSTRACT.pdf
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author Abdulmalek, Emilia
Mohd Saupi, Hanim Salami
Zulkefli, Syarilaida
Raja Abd Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
author_facet Abdulmalek, Emilia
Mohd Saupi, Hanim Salami
Zulkefli, Syarilaida
Raja Abd Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
author_sort Abdulmalek, Emilia
building UPM Institutional Repository
collection Online Access
description Thermostable T1 lipase from Geobacillus zalihae strain was utilized in esterification of various sugars with fatty acids to form fatty acid sugar esters. Fatty acid sugar esters (FASE) are an important class of non-ionic surfactant which possesses good emulsifying, stabilizing and conditioning properties. In this work the esterification reaction was done in [Bmim][BF4] ionic liquid with dimethylsulfoxide (DMSO) as co-solvent. Esterification of galactose with oleic acid was initially screened by varying the conditions (temperature, time, enzyme loading and the fatty acid chain length). It was found that the reaction was optimum at the following conditions: temperature (65 °C), time (120 minutes) and enzyme loading (2% (w/w)) when carried out in mixture of DMSO: [Bmim][BF4] (1:20). Interestingly, the percentage of conversion was not affected by the chain length of the acyl donor (C8 – C18) or the unsaturation degree. When the reaction was repeated with linoleic acid as acyl donor and different acyl acceptor (galactose, glucose, fructose, sucrose, maltose, trehalose and xylitol), sucrose gave the best conversion at 65%. In conclusion, TI lipase showed broad substrate specificity either for the acyl donor or acyl acceptor during the esterification of sugars in ionic liquid.
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institution Universiti Putra Malaysia
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language English
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publisher Faculty of Science and Technology, Universiti Kebangsaan Malaysia
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spelling upm-888362021-11-02T20:26:10Z http://psasir.upm.edu.my/id/eprint/88836/ Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid Abdulmalek, Emilia Mohd Saupi, Hanim Salami Zulkefli, Syarilaida Raja Abd Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin Thermostable T1 lipase from Geobacillus zalihae strain was utilized in esterification of various sugars with fatty acids to form fatty acid sugar esters. Fatty acid sugar esters (FASE) are an important class of non-ionic surfactant which possesses good emulsifying, stabilizing and conditioning properties. In this work the esterification reaction was done in [Bmim][BF4] ionic liquid with dimethylsulfoxide (DMSO) as co-solvent. Esterification of galactose with oleic acid was initially screened by varying the conditions (temperature, time, enzyme loading and the fatty acid chain length). It was found that the reaction was optimum at the following conditions: temperature (65 °C), time (120 minutes) and enzyme loading (2% (w/w)) when carried out in mixture of DMSO: [Bmim][BF4] (1:20). Interestingly, the percentage of conversion was not affected by the chain length of the acyl donor (C8 – C18) or the unsaturation degree. When the reaction was repeated with linoleic acid as acyl donor and different acyl acceptor (galactose, glucose, fructose, sucrose, maltose, trehalose and xylitol), sucrose gave the best conversion at 65%. In conclusion, TI lipase showed broad substrate specificity either for the acyl donor or acyl acceptor during the esterification of sugars in ionic liquid. Faculty of Science and Technology, Universiti Kebangsaan Malaysia 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88836/1/ABSTRACT.pdf Abdulmalek, Emilia and Mohd Saupi, Hanim Salami and Zulkefli, Syarilaida and Raja Abd Rahman, Raja Noor Zaliha and Abdul Rahman, Mohd Basyaruddin (2020) Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid. Malaysian Journal of Analytical Sciences, 24 (2). 188 - 196. ISSN 1394-2506 https://mjas.analis.com.my/mjas/v24_n2/html/24_2_5.html
spellingShingle Abdulmalek, Emilia
Mohd Saupi, Hanim Salami
Zulkefli, Syarilaida
Raja Abd Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title_full Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title_fullStr Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title_full_unstemmed Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title_short Enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
title_sort enzyme catalyzed esterification of sugar by thermostable t1 lipase from geobacillus zalihae in ionic liquid
url http://psasir.upm.edu.my/id/eprint/88836/
http://psasir.upm.edu.my/id/eprint/88836/
http://psasir.upm.edu.my/id/eprint/88836/1/ABSTRACT.pdf