Lipase catalysed synthesis of adipate wax esters in ionic liquid

Adipate wax ester shows excellent properties such as its low toxicity, good thermal stability, low volatility and high biodegradability, which made it as a very useful compound and significant to various industrial applications including pharmaceutical, food and coating. Green route organic synthesi...

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Main Authors: Abdul Rahman, Mohd Basyaruddin, Basri, Mahiran, Raja Abdul Rahman, Raja Noor Zaliha, Salleh, Abu Bakar
Format: Conference or Workshop Item
Language:English
Published: 2008
Online Access:http://psasir.upm.edu.my/id/eprint/8877/
http://psasir.upm.edu.my/id/eprint/8877/1/Lipase%20catalysed%20synthesis%20of%20adipate%20wax%20esters%20in%20ionic%20liquid.pdf
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author Abdul Rahman, Mohd Basyaruddin
Basri, Mahiran
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
author_facet Abdul Rahman, Mohd Basyaruddin
Basri, Mahiran
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
author_sort Abdul Rahman, Mohd Basyaruddin
building UPM Institutional Repository
collection Online Access
description Adipate wax ester shows excellent properties such as its low toxicity, good thermal stability, low volatility and high biodegradability, which made it as a very useful compound and significant to various industrial applications including pharmaceutical, food and coating. Green route organic synthesis via enzymatic synthesis, offers clean and mild reaction conditions provides an opportunity to increase productivity, efficiency and quality output. Considering the industrial importance of the ester, the optimal conditions for upscaling process was performed using Response Surface Methodology (RSM). Ionic liquid of [bmim]PF6 was used as a solvent in the esterification of different chain length of alcohol with adipic acid, and Novozyme as a biocatalyst. Higher percentage of yield (>80%) was obtained for longer alcohol chain (dioleyl adipate) but slightly lower yields were found for medium alcohol chain than in hexane. Ionic liquid become the major interest as it can recycled and remained the efficiency once compared to conventional organic solvent.
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format Conference or Workshop Item
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institution Universiti Putra Malaysia
institution_category Local University
language English
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publishDate 2008
recordtype eprints
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spelling upm-88772016-09-27T07:11:25Z http://psasir.upm.edu.my/id/eprint/8877/ Lipase catalysed synthesis of adipate wax esters in ionic liquid Abdul Rahman, Mohd Basyaruddin Basri, Mahiran Raja Abdul Rahman, Raja Noor Zaliha Salleh, Abu Bakar Adipate wax ester shows excellent properties such as its low toxicity, good thermal stability, low volatility and high biodegradability, which made it as a very useful compound and significant to various industrial applications including pharmaceutical, food and coating. Green route organic synthesis via enzymatic synthesis, offers clean and mild reaction conditions provides an opportunity to increase productivity, efficiency and quality output. Considering the industrial importance of the ester, the optimal conditions for upscaling process was performed using Response Surface Methodology (RSM). Ionic liquid of [bmim]PF6 was used as a solvent in the esterification of different chain length of alcohol with adipic acid, and Novozyme as a biocatalyst. Higher percentage of yield (>80%) was obtained for longer alcohol chain (dioleyl adipate) but slightly lower yields were found for medium alcohol chain than in hexane. Ionic liquid become the major interest as it can recycled and remained the efficiency once compared to conventional organic solvent. 2008-08-24 Conference or Workshop Item NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/8877/1/Lipase%20catalysed%20synthesis%20of%20adipate%20wax%20esters%20in%20ionic%20liquid.pdf Abdul Rahman, Mohd Basyaruddin and Basri, Mahiran and Raja Abdul Rahman, Raja Noor Zaliha and Salleh, Abu Bakar (2008) Lipase catalysed synthesis of adipate wax esters in ionic liquid. In: EUCHEM 2008 Conference on Molten Salts and Ionic Liquids, 24-29 Aug. 2008, Copenhagen, Denmark. .
spellingShingle Abdul Rahman, Mohd Basyaruddin
Basri, Mahiran
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
Lipase catalysed synthesis of adipate wax esters in ionic liquid
title Lipase catalysed synthesis of adipate wax esters in ionic liquid
title_full Lipase catalysed synthesis of adipate wax esters in ionic liquid
title_fullStr Lipase catalysed synthesis of adipate wax esters in ionic liquid
title_full_unstemmed Lipase catalysed synthesis of adipate wax esters in ionic liquid
title_short Lipase catalysed synthesis of adipate wax esters in ionic liquid
title_sort lipase catalysed synthesis of adipate wax esters in ionic liquid
url http://psasir.upm.edu.my/id/eprint/8877/
http://psasir.upm.edu.my/id/eprint/8877/1/Lipase%20catalysed%20synthesis%20of%20adipate%20wax%20esters%20in%20ionic%20liquid.pdf