Design and characterisation of inhibitory peptides against Bleg1_2478, an evolutionary divergent B3 metallo-β-lactamase
Previously, a hypothetical protein (HP) termed Bleg1_2437 (currently named Bleg1_2478) from Bacillus lehensis G1 was discovered to be an evolutionary divergent B3 subclass metallo-β-lactamase (MBL). Due to the scarcity of clinical inhibitors for B3 MBLs and the divergent nature of Bleg1_2478, this s...
| Main Authors: | Selvaraju, Gayathri, Leow, Adam Thean Chor, Salleh, Abu Bakar, Mohd Yahaya, Normi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2020
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/88366/ http://psasir.upm.edu.my/id/eprint/88366/1/ABSTRACT.pdf |
Similar Items
Design and characterization of inhibitory peptides against Bleg1_2478, B3 subclass Metallo-β-lactamase
by: Selvaraju, Gayathri
Published: (2021)
by: Selvaraju, Gayathri
Published: (2021)
Danger lurking in the ‘‘unknowns’’: structure-to-function studies of hypothetical protein Bleg1_2437 from Bacillus lehensis G1 alkaliphile revealed an evolutionary divergent B3 metallo-beta-lactamase
by: Tan, Soo Huei, et al.
Published: (2017)
by: Tan, Soo Huei, et al.
Published: (2017)
Dual activity bleg-1 from Bacillus Lehensis g1 revealed structural resemblance to b3 metallo-β-lactamase and glyoxalase ii: An insight into its enzyme promiscuity and evolutionary divergence
by: Au, Shaw Xian, et al.
Published: (2021)
by: Au, Shaw Xian, et al.
Published: (2021)
Probing the substrate binding modes and catalytic mechanisms of bleg-1, a promiscuous b3 metallo-β-lactamase with glyoxalase ii properties
by: Au, Shaw Xian, et al.
Published: (2023)
by: Au, Shaw Xian, et al.
Published: (2023)
Metallo-ä-lactamase-producing pseudomonas aeruginosa.
by: Mohd Taib, Niazlin, et al.
by: Mohd Taib, Niazlin, et al.
Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1
by: Tan, Soo Huei
Published: (2015)
by: Tan, Soo Huei
Published: (2015)
Computational design of artificial metallo-haloalkane dehalogenase
by: Ang, Thiau Fu, et al.
Published: (2015)
by: Ang, Thiau Fu, et al.
Published: (2015)
Identification and characterization of a promiscuous metallohydrolase in metallo-β-lactamase superfamily from a locally isolated organophosphate-degrading Bacillus sp. strain S3wahi
by: Azman, Ameera Aisyah, et al.
Published: (2024)
by: Azman, Ameera Aisyah, et al.
Published: (2024)
In silico design of potentially functional artificial metallo-haloalkane dehalogenase containing catalytic zinc
by: Thiau, Fu Ang, et al.
Published: (2018)
by: Thiau, Fu Ang, et al.
Published: (2018)
Prevalence of metallo-Beta-lactamase producing Pseudomonas aeruginosa in a tertiary care at Hospital Kuala Lumpur, Malaysia
by: Idris, Siti Nur Atiqah
Published: (2016)
by: Idris, Siti Nur Atiqah
Published: (2016)
Detection of Metallo-B-Lactamases-Encoding genes among clinical isolates of Escherichia Coli in a tertiary care hospital Malaysia
by: M. K. K., Fazlul, et al.
Published: (2019)
by: M. K. K., Fazlul, et al.
Published: (2019)
Ecological divergence and evolutionary transition of resprouting types in Banksia attenuata
by: He, Tianhua
Published: (2014)
by: He, Tianhua
Published: (2014)
Extended-spectrum β-lactamases-producing Escherichia coli from a tertiary hospital in Malaysia: emergence of CTX-M-type β-lactamases variation
by: Sekawi, Zamberi, et al.
Published: (2008)
by: Sekawi, Zamberi, et al.
Published: (2008)
Utilization and prospect of purification technologies in natural proteins, peptides and recombinant proteins
by: Eskandari, Azadeh, et al.
Published: (2024)
by: Eskandari, Azadeh, et al.
Published: (2024)
Novel peptides with antioxidant and angiotensin converting enzyme inhibitory activity
by: Saari, Nazamid, et al.
Published: (2013)
by: Saari, Nazamid, et al.
Published: (2013)
Production of a peptide composition with antioxidant and ace inhibitory properties
by: Saari, Nazamid, et al.
Published: (2013)
by: Saari, Nazamid, et al.
Published: (2013)
DNA barcoding in Nautilus pompilius (Mollusca:Cephalopoda): Evolutionary divergence of an ancient species in modern times
by: Williams, R., et al.
Published: (2012)
by: Williams, R., et al.
Published: (2012)
Extended spectrum beta-lactamase.
by: Masri, Siti Norbaya, et al.
Published: (2012)
by: Masri, Siti Norbaya, et al.
Published: (2012)
Factors Influencing The Optimization Of Organizational Sustainable Performance: A Case Study Of Pt. Mulia Realty Batindo In Batam, Indonesia
by: Selvaraju, Gayathri
Published: (2014)
by: Selvaraju, Gayathri
Published: (2014)
Screening for β-lactamase inhibitors from mangrove soil actinomycetes / Suhaidi Ariffin
by: Ariffin, Suhaidi
Published: (2016)
by: Ariffin, Suhaidi
Published: (2016)
Screening for β-lactamase inhibitors from mangrove soil actinomycetes / Suhaidi Ariffin
by: Ariffin, Suhaidi
Published: (2015)
by: Ariffin, Suhaidi
Published: (2015)
Genotypic and phenotypic characterization of methicillin resistance determinants and β-lactamase in Staphylococcus species
by: Abdul Rachman, Abdul Rahim, et al.
Published: (2017)
by: Abdul Rachman, Abdul Rahim, et al.
Published: (2017)
Pancreatic lipase inhibitory potential of selected Malaysian plants
by: Alias, Norsyuhada, et al.
Published: (2014)
by: Alias, Norsyuhada, et al.
Published: (2014)
Production of a peptide composition with ACE inhibitory properties from green soybean
by: Saari, Nazamid, et al.
Published: (2013)
by: Saari, Nazamid, et al.
Published: (2013)
Production of Angiotensin Converting Enzyme Inhibitory Peptides from Red Tilapia Protein Hydrolysates
by: Shamloo, Maryam
Published: (2010)
by: Shamloo, Maryam
Published: (2010)
Detection of virulence factors and β lactamase encoding genes among the clinical isolates of Pseudomonas aeruginosa
by: M. K. K., Fazlul, et al.
Published: (2018)
by: M. K. K., Fazlul, et al.
Published: (2018)
Extended spectrum beta-lactamases: definition, classification and epidemiology
by: Ghafourian, Sobhan, et al.
Published: (2015)
by: Ghafourian, Sobhan, et al.
Published: (2015)
Purification and characterization of nitric oxide inhibitory peptides from Actinopyga lecanora through enzymatic hydrolysis
by: Ghanbari, Raheleh, et al.
Published: (2016)
by: Ghanbari, Raheleh, et al.
Published: (2016)
Production of peptides with angiotensin-I converting enzyme (ACE) inhibitory properties from stichopus horrens
by: Saari, Nazamid, et al.
Published: (2013)
by: Saari, Nazamid, et al.
Published: (2013)
Novel furan-containing peptide-based inhibitors of protein arginine deiminase type IV (PAD4)
by: Teo, Chian Ying, et al.
Published: (2017)
by: Teo, Chian Ying, et al.
Published: (2017)
Phylogeography of two closely related Indo-Pacific butterflyfishes reveals divergent evolutionary histories and discordant results from mtDNA and microsatellites
by: Di Battista, Joseph, et al.
Published: (2012)
by: Di Battista, Joseph, et al.
Published: (2012)
Extraction And Identification Of Elastase Inhibitory Peptides From Digested Ovalbumin As Skin Anti-Aging
Therapeutics Agent
by: Chok, Wen Xin
Published: (2020)
by: Chok, Wen Xin
Published: (2020)
Optimization of metallo-keratinase production by Pseudomonas sp. LM19 as a potential enzyme for feather waste conversion
by: Mohamad, Nurliyana, et al.
Published: (2017)
by: Mohamad, Nurliyana, et al.
Published: (2017)
Discovery of new inhibitor for the protein arginine deiminase type 4 (PAD4) by rational design of α-enolase-derived peptides
by: Ahmad Nadzirin, Izzuddin, et al.
Published: (2021)
by: Ahmad Nadzirin, Izzuddin, et al.
Published: (2021)
Multidrug resistant, extended spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from a dairy farm
by: Ibrahim, Delveen, et al.
Published: (2016)
by: Ibrahim, Delveen, et al.
Published: (2016)
Evaluation of bioactive peptides from kenaf (Hibiscus cannabinus L.) seed protein for angiotensin-converting enzyme inhibitory activity
by: Zaharuddin, Nurul Dhania
Published: (2022)
by: Zaharuddin, Nurul Dhania
Published: (2022)
Optimizing of pharmaceutical active compounds biodegradability in secondary effluents by β-lactamase from Bacillus subtilis using central composite design
by: Al-Gheethi, Adel, et al.
Published: (2019)
by: Al-Gheethi, Adel, et al.
Published: (2019)
Purification and characterisation of angiotensin I converting enzyme (ACE) inhibitory peptide from blood cockle (Anadara granosa) meat hydrolysate
by: Aishah Suhaimi,, et al.
Published: (2020)
by: Aishah Suhaimi,, et al.
Published: (2020)
Divergence detectors for multitarget tracking algorithms
by: Mahler, Ronald
Published: (2013)
by: Mahler, Ronald
Published: (2013)
ASEAN ten economies: converge or diverge?
by: Habibullah, Muzafar Shah, et al.
Published: (2017)
by: Habibullah, Muzafar Shah, et al.
Published: (2017)
Similar Items
-
Design and characterization of inhibitory peptides against Bleg1_2478, B3 subclass Metallo-β-lactamase
by: Selvaraju, Gayathri
Published: (2021) -
Danger lurking in the ‘‘unknowns’’: structure-to-function studies of hypothetical protein Bleg1_2437 from Bacillus lehensis G1 alkaliphile revealed an evolutionary divergent B3 metallo-beta-lactamase
by: Tan, Soo Huei, et al.
Published: (2017) -
Dual activity bleg-1 from Bacillus Lehensis g1 revealed structural resemblance to b3 metallo-β-lactamase and glyoxalase ii: An insight into its enzyme promiscuity and evolutionary divergence
by: Au, Shaw Xian, et al.
Published: (2021) -
Probing the substrate binding modes and catalytic mechanisms of bleg-1, a promiscuous b3 metallo-β-lactamase with glyoxalase ii properties
by: Au, Shaw Xian, et al.
Published: (2023) -
Metallo-ä-lactamase-producing pseudomonas aeruginosa.
by: Mohd Taib, Niazlin, et al.