Combining PARP inhibition with platinum, ruthenium or gold complexes for cancer therapy

QR Code

Combining PARP inhibition with platinum, ruthenium or gold complexes for cancer therapy

Platinum drugs are heavily used first-line chemotherapeutic agents for many solid tumours and have stimulated substantial interest in the biological activity of DNA-binding metal complexes. These complexes generate DNA lesions which trigger the activation of DNA damage response (DDR) pathways that a...

Full description

Bibliographic Details
Main Authors:	Yusoh, Nur Aininie, Ahmad, Haslina, Gill, Martin R.
Format:	Article
Language:	English
Published:	John Wiley and Sons 2020
Online Access:	http://psasir.upm.edu.my/id/eprint/88194/ http://psasir.upm.edu.my/id/eprint/88194/1/ABSTRACT.pdf

Similar Items

Effect of combination therapy of ruthenium polypyridyl complex, [Ru(dppz)2(PIP)]2+ and parp inhibitors against several cancer cell lines
by: Yusoh, Nur Aininie
Published: (2020)

Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
by: Yusoh, Nur Aininie, et al.
Published: (2023)

PARP inhibitor combinations with Olaparib for synergistic efficacy in Olaparib-resistant triple-negative breast cancer cells
by: Yusoh, Nur Aininie
Published: (2023)

Discovery of ruthenium(ii) metallocompound and olaparib synergy for cancer combination therapy
by: Yusoh, Nur Aininie, et al.
Published: (2023)

Metallointercalator [Ru(dppz)2(PIP)]2+ renders BRCA wild-type triple-negative breast cancer cells hypersensitive to PARP inhibition
by: Yusoh, Nur Aininie, et al.
Published: (2020)

Ruthenium(ii) Polypyridyl complexes as FRET donors: structure- and sequence-selective DNA binding and anti-cancer properties
by: E. Elgar, Christopher, et al.
Published: (2023)

Clinicopathological features of homologous recombination deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum and survival
by: Mukhophadyay, Asima, et al.
Published: (2012)

Ruthenium(II) Polypyridyl Complexes as FRET donors: structure- and sequence-selective DNA-binding and anticancer properties
by: Elgar, Christopher E., et al.
Published: (2023)

A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
by: Gill, Martin R., et al.
Published: (2016)

Structure and corrosion behavior of platinum/ruthenium/nitrogen doped diamondlike carbon thin films
by: Khun, N.W., et al.
Published: (2009)

Fabrication of porcine DNA biosensor based on ruthenium bipyridine complex
by: Abdullah Halid, Nurul Izni, et al.
Published: (2016)

Synthesis and optimization of mesoporous silica nanoparticles for ruthenium polypyridyl drug delivery
by: Harun, Siti Norain, et al.
Published: (2021)

Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013)

An electrochemical DNA biosensor based gold-thiolate conjugation utilizing ruthenium complex [Ru(dppz)2(qtpy)]Cl2
by: Foo, K. L., et al.
Published: (2016)

Potential association of nicotinamide on the telomerase activity and telomere length mediated by PARP-1 mechanism in myeloid cancer
by: Nur Rasyidah Muhammad,, et al.
Published: (2020)

Platinum(II) Complexes for Biological Applications
by: Grady, Thomas James
Published: (2021)

High pressure studies of palladium and platinum thioether macrocyclic dihalide complexes
by: Schröder, Martin
Published: (2014)

Arene ruthenium chemistry
by: Bates, Richard Simon
Published: (1990)

Electrochemical DNA biosensor for detection of porcine oligonucleotides using ruthenium(II) complex as intercalator label redox
by: Abdullah Halid, Nurul Izni, et al.
Published: (2014)

Synthesis, characterization and DNA binding studies of luminescent ruthenium(ii) imidazo complexes
by: Ting, Timothy Tze Chun
Published: (2014)

Synthesis, cytotoxicity and dna binding studies of ruthenium(ii) mixed-polypyridyl complexes
by: Harun, Siti Norain
Published: (2015)

Curcumin combination therapy: the implication and efficacy in cancer
by: Bee, Ling Tan, et al.
Published: (2019)

Epoxidized Natural Rubber (Enr-50) Stabilized Gold And Platinum Organosols
by: Teoh, Cheng Hoon
Published: (2006)

An electrochemical DNA biosensor based gold-thiolate conjugation utilizing ruthenium complex [Ru(dppz)<inf>2</inf>(qtpy)]Cl<inf>2</inf>
by: Foo, K.L., et al.
Published: (2017)

A novel ruthenium-tungsten bimetallic complex dye-sensitizer for photoelectrochemical cells application
by: Khuzaimah Arifin,, et al.
Published: (2014)

Dithiocarbamate complexes of platinum group metals: Structural aspects and applications
by: Tan, Yee Seng *, et al.
Published: (2021)

Can the relative price ratio of gold to platinum predict the Chinese stock market?
by: Han, Xing, et al.
Published: (2020)

Doxorubicin-loaded magnetic gold nanoshells for a combination therapy of hyperthermia and drug delivery
by: Mohammad, Faruq, et al.
Published: (2014)

Multifunctional Gold-Silica Composite Platform Towards Comprehensive Cancer Therapy
by: Tew, Lih Shin
Published: (2018)

Some ruthenium complexes containing cyanocarbon ligands: syntheses, structures and extent of electronic communication in binuclear systems
by: Bruce, M., et al.
Published: (2004)

Biological evaluation of folic acid functionalized nano‐zeolitic imidazolate framework‐8 for cancer therapy
by: Lai, Xie Yong, et al.
Published: (2024)

Synthesis, characterization and biological activities of acridine derivatives and their platinum complexes / Nur Amajeida Ismail
by: Nur Amajeida , Ismail
Published: (2018)

Proton-induced reversible modulation of the luminescent output of rhenium(I), iridium(III), and ruthenium(II) tetrazolate complexes
by: Werrett, Melissa, et al.
Published: (2014)

Synthesis and characterization of bipyridine and dipyridophenazine based ruthenium (ii) complexes as potential dye-sensitized solar cells sensitizers
by: Chan, Keng Fuong
Published: (2018)

Ethanol induces microglial cell death via the NOX/ROS/PARP/TRPM2 signalling pathway
by: Sha’fie, Muhammad Syahreel Azhad, et al.
Published: (2020)

Effects of nicotinamide and nilotinib on telomerase activity and telomere length associated with parp-1 regulation in k562 myeloid cell line
by: Muhammad, Nur Rasyidah
Published: (2023)

Elastic properties and lattice dynamics of ruthenium at high pressures
by: Lugovskoy, Andrey, et al.
Published: (2014)

The Recovery of Platinum, Palladium, and Gold from a Cyanide Heap Solution, with use of Ion Exchange Resins
by: Schoeman, E., et al.
Published: (2013)

UMP won special platinum award and five gold medals in the British Invention Show (BIS) 2013
by: Noor Syahidah, Sabran
Published: (2013)

Combination effect of photodynamic therapy (pdt) and chemotherapy on oral cancer cell lines
by: Teoh, Jia Jie
Published: (2012)