Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties
In this study, calcium oxide (CaO) nanoparticles (Nps) were obtained by biosynthesis through the deposition and precipitation of calcium carbonate (CaCO3) in Trigona sp. honey. The FESEM images showed a spherical morphology with an average Nps size below 100 nm, whereas the AFM images demonstrated i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/88044/ http://psasir.upm.edu.my/id/eprint/88044/1/ABSTRACT.pdf |
| _version_ | 1848860544419758080 |
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| author | Maringgal, Bernard Hashim, Norhashila Tawakkal, Intan S. M. A. Hamzah, Muhammad Hazwan Mohamed, Mahmud Tengku Muda |
| author_facet | Maringgal, Bernard Hashim, Norhashila Tawakkal, Intan S. M. A. Hamzah, Muhammad Hazwan Mohamed, Mahmud Tengku Muda |
| author_sort | Maringgal, Bernard |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this study, calcium oxide (CaO) nanoparticles (Nps) were obtained by biosynthesis through the deposition and precipitation of calcium carbonate (CaCO3) in Trigona sp. honey. The FESEM images showed a spherical morphology with an average Nps size below 100 nm, whereas the AFM images demonstrated its average height of 2.3 nm. The XRD pattern analysis resulted in sharper peaks indicative of CaO Nps that were well-crystallised. Further calculation of the average particle size by using the Debye-Scherrer equation yielded the value of 51.64 nm, whereas the FTIR spectrum showed the intensive peaks of the hydroxyl and carboxylic groups, amines, and amides. Accordingly, these biosynthesised CaO Nps generated at 15 % concentration displayed maximum inhibition against the anthracnose disease. They were found to be nontoxic when analysed through a cytotoxicity test against the MRC 5 cells and VERO cells. |
| first_indexed | 2025-11-15T12:46:55Z |
| format | Article |
| id | upm-88044 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:46:55Z |
| publishDate | 2020 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-880442022-05-24T04:00:11Z http://psasir.upm.edu.my/id/eprint/88044/ Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties Maringgal, Bernard Hashim, Norhashila Tawakkal, Intan S. M. A. Hamzah, Muhammad Hazwan Mohamed, Mahmud Tengku Muda In this study, calcium oxide (CaO) nanoparticles (Nps) were obtained by biosynthesis through the deposition and precipitation of calcium carbonate (CaCO3) in Trigona sp. honey. The FESEM images showed a spherical morphology with an average Nps size below 100 nm, whereas the AFM images demonstrated its average height of 2.3 nm. The XRD pattern analysis resulted in sharper peaks indicative of CaO Nps that were well-crystallised. Further calculation of the average particle size by using the Debye-Scherrer equation yielded the value of 51.64 nm, whereas the FTIR spectrum showed the intensive peaks of the hydroxyl and carboxylic groups, amines, and amides. Accordingly, these biosynthesised CaO Nps generated at 15 % concentration displayed maximum inhibition against the anthracnose disease. They were found to be nontoxic when analysed through a cytotoxicity test against the MRC 5 cells and VERO cells. Elsevier 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88044/1/ABSTRACT.pdf Maringgal, Bernard and Hashim, Norhashila and Tawakkal, Intan S. M. A. and Hamzah, Muhammad Hazwan and Mohamed, Mahmud Tengku Muda (2020) Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties. Journal of Materials Research and Technology-JMR&T, 9 (5). 11756 - 11768. ISSN 2238-7854; ESSN: 2214-0697 https://www.sciencedirect.com/science/article/pii/S2238785420316616 10.1016/j.jmrt.2020.08.054 |
| spellingShingle | Maringgal, Bernard Hashim, Norhashila Tawakkal, Intan S. M. A. Hamzah, Muhammad Hazwan Mohamed, Mahmud Tengku Muda Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title | Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title_full | Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title_fullStr | Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title_full_unstemmed | Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title_short | Biosynthesis of CaO nanoparticles using Trigona sp. Honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| title_sort | biosynthesis of cao nanoparticles using trigona sp. honey: physicochemical characterization, antifungal activity, and cytotoxicity properties |
| url | http://psasir.upm.edu.my/id/eprint/88044/ http://psasir.upm.edu.my/id/eprint/88044/ http://psasir.upm.edu.my/id/eprint/88044/ http://psasir.upm.edu.my/id/eprint/88044/1/ABSTRACT.pdf |