A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran

The increased fungi contaminations and related damages cause disease through production of toxins in animals and thus in humans. Since they are not easily distinguishable, then it is crucial to study their characteristics. Aspergillus are among the most important toxigenic fungi that are found abund...

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Main Authors: Firouzmand, Raheleh, Modiri, Leila, Sabet, Negar Shafiei, Doustjalali, Saeid Reza, Nosrati, Arash Chaichi, Fashtali, Soheyl Shokri, Mirhasheminasab, Seyyed Amirhossein, Mansor, Marzalina, MHM, Nazmul, Mohd Desa, Mohd Nasir, Hussaini, Jamal
Format: Article
Language:English
Published: Medknow Publications 2020
Online Access:http://psasir.upm.edu.my/id/eprint/87723/
http://psasir.upm.edu.my/id/eprint/87723/1/ABSTRACT.pdf
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author Firouzmand, Raheleh
Modiri, Leila
Sabet, Negar Shafiei
Doustjalali, Saeid Reza
Nosrati, Arash Chaichi
Fashtali, Soheyl Shokri
Mirhasheminasab, Seyyed Amirhossein
Mansor, Marzalina
MHM, Nazmul
Mohd Desa, Mohd Nasir
Hussaini, Jamal
author_facet Firouzmand, Raheleh
Modiri, Leila
Sabet, Negar Shafiei
Doustjalali, Saeid Reza
Nosrati, Arash Chaichi
Fashtali, Soheyl Shokri
Mirhasheminasab, Seyyed Amirhossein
Mansor, Marzalina
MHM, Nazmul
Mohd Desa, Mohd Nasir
Hussaini, Jamal
author_sort Firouzmand, Raheleh
building UPM Institutional Repository
collection Online Access
description The increased fungi contaminations and related damages cause disease through production of toxins in animals and thus in humans. Since they are not easily distinguishable, then it is crucial to study their characteristics. Aspergillus are among the most important toxigenic fungi that are found abundantly in northern Iran habitat which is one of most important habitat of Iran and is the main source for many feed and food stuffs in the state. Hence, we aimed to study on properties of deoxynivalenol (DON) production in culture medium by 24 Aspergillus spp. isolates from northern Iran. Samples were collected from Northern Alborz and Southern Caspian Sea agricultural plants cultivation areas and processing centers. Samples were then isolated and identified based on CBS environmental sampling rules and ICPA diagnostic standards. They were cultured to stimulate the toxin production until the targeted toxin to be measured at culturing substrate and fungi biomass. Afterward, they were exposed to extraction and existing DON size were measured by ELISA technique Our results indicated that in addition to Fusarium, genus Aspergillus has a potent ability to produce DON toxin or alike molecules. However, validation of this issue needs further studies, in particular, by using advanced biochemical or genomic molecular techniques.
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institution Universiti Putra Malaysia
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publisher Medknow Publications
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spelling upm-877232022-07-06T03:14:00Z http://psasir.upm.edu.my/id/eprint/87723/ A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran Firouzmand, Raheleh Modiri, Leila Sabet, Negar Shafiei Doustjalali, Saeid Reza Nosrati, Arash Chaichi Fashtali, Soheyl Shokri Mirhasheminasab, Seyyed Amirhossein Mansor, Marzalina MHM, Nazmul Mohd Desa, Mohd Nasir Hussaini, Jamal The increased fungi contaminations and related damages cause disease through production of toxins in animals and thus in humans. Since they are not easily distinguishable, then it is crucial to study their characteristics. Aspergillus are among the most important toxigenic fungi that are found abundantly in northern Iran habitat which is one of most important habitat of Iran and is the main source for many feed and food stuffs in the state. Hence, we aimed to study on properties of deoxynivalenol (DON) production in culture medium by 24 Aspergillus spp. isolates from northern Iran. Samples were collected from Northern Alborz and Southern Caspian Sea agricultural plants cultivation areas and processing centers. Samples were then isolated and identified based on CBS environmental sampling rules and ICPA diagnostic standards. They were cultured to stimulate the toxin production until the targeted toxin to be measured at culturing substrate and fungi biomass. Afterward, they were exposed to extraction and existing DON size were measured by ELISA technique Our results indicated that in addition to Fusarium, genus Aspergillus has a potent ability to produce DON toxin or alike molecules. However, validation of this issue needs further studies, in particular, by using advanced biochemical or genomic molecular techniques. Medknow Publications 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/87723/1/ABSTRACT.pdf Firouzmand, Raheleh and Modiri, Leila and Sabet, Negar Shafiei and Doustjalali, Saeid Reza and Nosrati, Arash Chaichi and Fashtali, Soheyl Shokri and Mirhasheminasab, Seyyed Amirhossein and Mansor, Marzalina and MHM, Nazmul and Mohd Desa, Mohd Nasir and Hussaini, Jamal (2020) A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran. Systematic Reviews in Pharmacy, 11 (3). 773 - 785. ISSN 0975-8453; ESSN: 0976-2779 https://www.sysrevpharm.org/abstract/a-study-on-properties-of-deoxynivalenol-don-production-in-culture-medium-by-aspergillus-spp-isolates-from-northern-iran-66721.html 10.31838/srp.2020.3.108
spellingShingle Firouzmand, Raheleh
Modiri, Leila
Sabet, Negar Shafiei
Doustjalali, Saeid Reza
Nosrati, Arash Chaichi
Fashtali, Soheyl Shokri
Mirhasheminasab, Seyyed Amirhossein
Mansor, Marzalina
MHM, Nazmul
Mohd Desa, Mohd Nasir
Hussaini, Jamal
A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title_full A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title_fullStr A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title_full_unstemmed A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title_short A study on properties of Deoxynivalenol (DON) production in culture medium by Aspergillus Spp. isolates from Northern Iran
title_sort study on properties of deoxynivalenol (don) production in culture medium by aspergillus spp. isolates from northern iran
url http://psasir.upm.edu.my/id/eprint/87723/
http://psasir.upm.edu.my/id/eprint/87723/
http://psasir.upm.edu.my/id/eprint/87723/
http://psasir.upm.edu.my/id/eprint/87723/1/ABSTRACT.pdf