Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia
A study was conducted to screen the occurrence and level of aflatoxin M1 (AFM1) in urine samples of 206 urban and rural residents in Terengganu, Malaysia. The level of AFM1 was quantified by competitive enzyme-linked immune-absorbent assay (ELISA). Of the 206 samples, 84 were positive for AFM1 (40.8...
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| Format: | Article |
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Elsevier
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/87534/ |
| _version_ | 1848860452835033088 |
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| author | Ahmad, Farah Nadira Jamaluddin, Rosita Mohd Esa, Norhaizan |
| author_facet | Ahmad, Farah Nadira Jamaluddin, Rosita Mohd Esa, Norhaizan |
| author_sort | Ahmad, Farah Nadira |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A study was conducted to screen the occurrence and level of aflatoxin M1 (AFM1) in urine samples of 206 urban and rural residents in Terengganu, Malaysia. The level of AFM1 was quantified by competitive enzyme-linked immune-absorbent assay (ELISA). Of the 206 samples, 84 were positive for AFM1 (40.8%) in a range of 0.07–5.53 ng/ml (mean = 0.589 ng/ml). Residents of Terengganu are moderately exposed to AFM1. Age, ethnicity, marital status and employment status were associated with urinary level of AFM1. Subjects aged 30 years and above, non-Malays, married, and those unemployed had significantly higher levels of urinary AFM1 (p < 0.05). Since aflatoxin is recognised as a potent-carcinogen for liver cancer and a continuous exposure to this toxin can be fatal, the present findings could provide a baseline for future studies where larger samples and more advanced techniques might be used to find the possible effects of the exposure of this toxin on the community's health. |
| first_indexed | 2025-11-15T12:45:28Z |
| format | Article |
| id | upm-87534 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T12:45:28Z |
| publishDate | 2020 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-875342022-11-23T02:31:34Z http://psasir.upm.edu.my/id/eprint/87534/ Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia Ahmad, Farah Nadira Jamaluddin, Rosita Mohd Esa, Norhaizan A study was conducted to screen the occurrence and level of aflatoxin M1 (AFM1) in urine samples of 206 urban and rural residents in Terengganu, Malaysia. The level of AFM1 was quantified by competitive enzyme-linked immune-absorbent assay (ELISA). Of the 206 samples, 84 were positive for AFM1 (40.8%) in a range of 0.07–5.53 ng/ml (mean = 0.589 ng/ml). Residents of Terengganu are moderately exposed to AFM1. Age, ethnicity, marital status and employment status were associated with urinary level of AFM1. Subjects aged 30 years and above, non-Malays, married, and those unemployed had significantly higher levels of urinary AFM1 (p < 0.05). Since aflatoxin is recognised as a potent-carcinogen for liver cancer and a continuous exposure to this toxin can be fatal, the present findings could provide a baseline for future studies where larger samples and more advanced techniques might be used to find the possible effects of the exposure of this toxin on the community's health. Elsevier 2020-10-30 Article PeerReviewed Ahmad, Farah Nadira and Jamaluddin, Rosita and Mohd Esa, Norhaizan (2020) Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia. Toxicon, 186. 120 - 125. ISSN 0041-0101 https://www.sciencedirect.com/science/article/pii/S0041010120303263 10.1016/j.toxicon.2020.07.022 |
| spellingShingle | Ahmad, Farah Nadira Jamaluddin, Rosita Mohd Esa, Norhaizan Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title | Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title_full | Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title_fullStr | Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title_full_unstemmed | Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title_short | Screening of aflatoxin M1 metabolite in urine samples of residents in Terengganu, Malaysia |
| title_sort | screening of aflatoxin m1 metabolite in urine samples of residents in terengganu, malaysia |
| url | http://psasir.upm.edu.my/id/eprint/87534/ http://psasir.upm.edu.my/id/eprint/87534/ http://psasir.upm.edu.my/id/eprint/87534/ |