Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review

Chitosan, collagen, gelatin, polylactic acid and polyhydroxyalkanoates are notable examples of biopolymers, which are essentially bio-derived polymers produced by living cells. With the right techniques, these biological macromolecules can be exploited for nanotechnological advents, including for th...

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Main Authors: Samrot, Antony V., tan, Chuan Sean, Kudaiyappan, Teeshalini, Ummu Bisyarah, Mirarmandi, Anita, Faradjeva, Etel, Abu Bakar, Amirah, Ali, Hawwa Hashma, J., Lavanya Agnes Angalene, Subbiah, Suresh Kumar
Format: Article
Language:English
Published: Elsevier 2020
Online Access:http://psasir.upm.edu.my/id/eprint/87323/
http://psasir.upm.edu.my/id/eprint/87323/1/Production%2C%20characterization%20and%20application%20%281%29.pdf
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author Samrot, Antony V.
tan, Chuan Sean
Kudaiyappan, Teeshalini
Ummu Bisyarah
Mirarmandi, Anita
Faradjeva, Etel
Abu Bakar, Amirah
Ali, Hawwa Hashma
J., Lavanya Agnes Angalene
Subbiah, Suresh Kumar
author_facet Samrot, Antony V.
tan, Chuan Sean
Kudaiyappan, Teeshalini
Ummu Bisyarah
Mirarmandi, Anita
Faradjeva, Etel
Abu Bakar, Amirah
Ali, Hawwa Hashma
J., Lavanya Agnes Angalene
Subbiah, Suresh Kumar
author_sort Samrot, Antony V.
building UPM Institutional Repository
collection Online Access
description Chitosan, collagen, gelatin, polylactic acid and polyhydroxyalkanoates are notable examples of biopolymers, which are essentially bio-derived polymers produced by living cells. With the right techniques, these biological macromolecules can be exploited for nanotechnological advents, including for the fabrication of nanocarriers. In the world of nanotechnology, it is highly essential (and optimal) for nanocarriers to be biocompatible, biodegradable and non-toxic for safe in vivo applications, including for drug delivery, cancer immunotherapy, tissue engineering, gene delivery, photodynamic therapy and many more. The recent advancements in understanding nanotechnology and the physicochemical properties of biopolymers allows us to modify biological macromolecules and use them in a multitude of fields, most notably for clinical and therapeutic applications. By utilizing chitosan, collagen, gelatin, polylactic acid, polyhydroxyalkanoates and various other biopolymers as synthesis ingredients, the ‘optimal’ properties of a nanocarrier can easily be attained. With emphasis on the aforementioned biological macromolecules, this review presents the various biopolymers utilized for nanocarrier synthesis along with their specific synthetization methods. We further discussed on the characterization techniques and related applications for the synthesized nanocarriers.
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spelling upm-873232022-09-05T04:11:53Z http://psasir.upm.edu.my/id/eprint/87323/ Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review Samrot, Antony V. tan, Chuan Sean Kudaiyappan, Teeshalini Ummu Bisyarah Mirarmandi, Anita Faradjeva, Etel Abu Bakar, Amirah Ali, Hawwa Hashma J., Lavanya Agnes Angalene Subbiah, Suresh Kumar Chitosan, collagen, gelatin, polylactic acid and polyhydroxyalkanoates are notable examples of biopolymers, which are essentially bio-derived polymers produced by living cells. With the right techniques, these biological macromolecules can be exploited for nanotechnological advents, including for the fabrication of nanocarriers. In the world of nanotechnology, it is highly essential (and optimal) for nanocarriers to be biocompatible, biodegradable and non-toxic for safe in vivo applications, including for drug delivery, cancer immunotherapy, tissue engineering, gene delivery, photodynamic therapy and many more. The recent advancements in understanding nanotechnology and the physicochemical properties of biopolymers allows us to modify biological macromolecules and use them in a multitude of fields, most notably for clinical and therapeutic applications. By utilizing chitosan, collagen, gelatin, polylactic acid, polyhydroxyalkanoates and various other biopolymers as synthesis ingredients, the ‘optimal’ properties of a nanocarrier can easily be attained. With emphasis on the aforementioned biological macromolecules, this review presents the various biopolymers utilized for nanocarrier synthesis along with their specific synthetization methods. We further discussed on the characterization techniques and related applications for the synthesized nanocarriers. Elsevier 2020-12 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/87323/1/Production%2C%20characterization%20and%20application%20%281%29.pdf Samrot, Antony V. and tan, Chuan Sean and Kudaiyappan, Teeshalini and Ummu Bisyarah and Mirarmandi, Anita and Faradjeva, Etel and Abu Bakar, Amirah and Ali, Hawwa Hashma and J., Lavanya Agnes Angalene and Subbiah, Suresh Kumar (2020) Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review. International Journal of Biological Macromolecules, 165 (15). pp. 3088-3105. ISSN 0141-8130; ESSN: 1879-0003 https://www.sciencedirect.com/journal/international-journal-of-biological-macromolecules/vol/165/part/PB 10.1016/j.ijbiomac.2020.10.104
spellingShingle Samrot, Antony V.
tan, Chuan Sean
Kudaiyappan, Teeshalini
Ummu Bisyarah
Mirarmandi, Anita
Faradjeva, Etel
Abu Bakar, Amirah
Ali, Hawwa Hashma
J., Lavanya Agnes Angalene
Subbiah, Suresh Kumar
Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title_full Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title_fullStr Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title_full_unstemmed Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title_short Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
title_sort production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: a review
url http://psasir.upm.edu.my/id/eprint/87323/
http://psasir.upm.edu.my/id/eprint/87323/
http://psasir.upm.edu.my/id/eprint/87323/
http://psasir.upm.edu.my/id/eprint/87323/1/Production%2C%20characterization%20and%20application%20%281%29.pdf