Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution

Aims: To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution.Methods: This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrin...

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Main Authors: Safri, Lenny Suryani, Tan, Henry Chor Lip, Saripan, M. Iqbal, K., Krishnan, Md Idris, Mohamad Aziman, Harunarashid, Hanafiah
Format: Article
Language:English
Published: Elsevier 2020
Online Access:http://psasir.upm.edu.my/id/eprint/86965/
http://psasir.upm.edu.my/id/eprint/86965/1/Older%20age%20and%20duration%20of%20exposure%20to%20type%202%20diabetes.pdf
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author Safri, Lenny Suryani
Tan, Henry Chor Lip
Saripan, M. Iqbal
K., Krishnan
Md Idris, Mohamad Aziman
Harunarashid, Hanafiah
author_facet Safri, Lenny Suryani
Tan, Henry Chor Lip
Saripan, M. Iqbal
K., Krishnan
Md Idris, Mohamad Aziman
Harunarashid, Hanafiah
author_sort Safri, Lenny Suryani
building UPM Institutional Repository
collection Online Access
description Aims: To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution.Methods: This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrine clinics for carotid duplex ultrasound scanning performed by a single radiologist. The duplex ultrasound criteria were based on the North American Symptomatic Carotid Endarterectomy Trial (NASCET) classification of carotid artery stenosis. Univariate and multivariate analysis was performed to identify possible risk factors of carotid artery stenosis.Results: Amongst the 200 patients, the majority were males (56%) and Malay predominance (58.5%). There were 12/200 patients (6%) with mean age of 69.2 years identified to have carotid artery stenosis. Univariate analysis of patients with asymptomatic carotid artery stenosis identified older age of 69.2 years (p = 0.027) and duration of exposure to diabetes of 17.9 years (p = 0.024) as significant risk factors.Conclusion: Patients with longer exposure of diabetes and older age were risk factors of carotid artery stenosis in asymptomatic type 2 diabetics. These patients should be considered for selective screening of carotid artery stenosis during primary care visit for early identification and closer surveillance for stroke prevention.
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spelling upm-869652022-09-05T03:11:50Z http://psasir.upm.edu.my/id/eprint/86965/ Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution Safri, Lenny Suryani Tan, Henry Chor Lip Saripan, M. Iqbal K., Krishnan Md Idris, Mohamad Aziman Harunarashid, Hanafiah Aims: To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution.Methods: This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrine clinics for carotid duplex ultrasound scanning performed by a single radiologist. The duplex ultrasound criteria were based on the North American Symptomatic Carotid Endarterectomy Trial (NASCET) classification of carotid artery stenosis. Univariate and multivariate analysis was performed to identify possible risk factors of carotid artery stenosis.Results: Amongst the 200 patients, the majority were males (56%) and Malay predominance (58.5%). There were 12/200 patients (6%) with mean age of 69.2 years identified to have carotid artery stenosis. Univariate analysis of patients with asymptomatic carotid artery stenosis identified older age of 69.2 years (p = 0.027) and duration of exposure to diabetes of 17.9 years (p = 0.024) as significant risk factors.Conclusion: Patients with longer exposure of diabetes and older age were risk factors of carotid artery stenosis in asymptomatic type 2 diabetics. These patients should be considered for selective screening of carotid artery stenosis during primary care visit for early identification and closer surveillance for stroke prevention. Elsevier 2020-08-01 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/86965/1/Older%20age%20and%20duration%20of%20exposure%20to%20type%202%20diabetes.pdf Safri, Lenny Suryani and Tan, Henry Chor Lip and Saripan, M. Iqbal and K., Krishnan and Md Idris, Mohamad Aziman and Harunarashid, Hanafiah (2020) Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution. Primary Care Diabetes, 14 (4). 364 - 369. ISSN 1751-9918 https://www.sciencedirect.com/science/article/pii/S1751991819304012?via%3Dihub
spellingShingle Safri, Lenny Suryani
Tan, Henry Chor Lip
Saripan, M. Iqbal
K., Krishnan
Md Idris, Mohamad Aziman
Harunarashid, Hanafiah
Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title_full Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title_fullStr Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title_full_unstemmed Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title_short Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
title_sort older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention - a experience single institution
url http://psasir.upm.edu.my/id/eprint/86965/
http://psasir.upm.edu.my/id/eprint/86965/
http://psasir.upm.edu.my/id/eprint/86965/1/Older%20age%20and%20duration%20of%20exposure%20to%20type%202%20diabetes.pdf