Nodal histiocytic disorder in children: report of three cases and review of literature
Background: Histiocytic system consists of phagocytes and dendritic cells. Both are found in lymph nodes. Usually, this disorder presents with painless cervical lymph node enlargement hence frequently mistaken for lymphoma or tuberculosis. Case presentation: Here, we report three pediatric cases: on...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Springer
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/86909/ http://psasir.upm.edu.my/id/eprint/86909/1/Nodal%20histiocytic%20disorder%20in%20children.pdf |
| _version_ | 1848860319076581376 |
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| author | Ainer, Indumathi Gendeh, Hardip Singh Husain, Salina Mohd Nor, Khadijah |
| author_facet | Ainer, Indumathi Gendeh, Hardip Singh Husain, Salina Mohd Nor, Khadijah |
| author_sort | Ainer, Indumathi |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Histiocytic system consists of phagocytes and dendritic cells. Both are found in lymph nodes. Usually, this disorder presents with painless cervical lymph node enlargement hence frequently mistaken for lymphoma or tuberculosis. Case presentation: Here, we report three pediatric cases: one of Langerhans cell histiocytosis and two of sinus histiocytosis and massive lymphadenopathy with neck mass as initial presentation. The final diagnosis was made with fine needle aspiration cytology, biopsy, and ancillary tests. Conclusion: Biopsy and immunohistochemistry studies are recommended for determining subtypes of histiocytosis and further management of patient. |
| first_indexed | 2025-11-15T12:43:20Z |
| format | Article |
| id | upm-86909 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:43:20Z |
| publishDate | 2020 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-869092022-01-03T02:56:49Z http://psasir.upm.edu.my/id/eprint/86909/ Nodal histiocytic disorder in children: report of three cases and review of literature Ainer, Indumathi Gendeh, Hardip Singh Husain, Salina Mohd Nor, Khadijah Background: Histiocytic system consists of phagocytes and dendritic cells. Both are found in lymph nodes. Usually, this disorder presents with painless cervical lymph node enlargement hence frequently mistaken for lymphoma or tuberculosis. Case presentation: Here, we report three pediatric cases: one of Langerhans cell histiocytosis and two of sinus histiocytosis and massive lymphadenopathy with neck mass as initial presentation. The final diagnosis was made with fine needle aspiration cytology, biopsy, and ancillary tests. Conclusion: Biopsy and immunohistochemistry studies are recommended for determining subtypes of histiocytosis and further management of patient. Springer 2020-12-03 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/86909/1/Nodal%20histiocytic%20disorder%20in%20children.pdf Ainer, Indumathi and Gendeh, Hardip Singh and Husain, Salina and Mohd Nor, Khadijah (2020) Nodal histiocytic disorder in children: report of three cases and review of literature. Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 36. art. no. 33. pp. 1-5. ISSN 2090-0740; ESSN: 2090-3405 https://ejo.springeropen.com/articles/10.1186/s43163-020-00035-z 10.1186/s43163-020-00035-z |
| spellingShingle | Ainer, Indumathi Gendeh, Hardip Singh Husain, Salina Mohd Nor, Khadijah Nodal histiocytic disorder in children: report of three cases and review of literature |
| title | Nodal histiocytic disorder in children: report of three cases and review of literature |
| title_full | Nodal histiocytic disorder in children: report of three cases and review of literature |
| title_fullStr | Nodal histiocytic disorder in children: report of three cases and review of literature |
| title_full_unstemmed | Nodal histiocytic disorder in children: report of three cases and review of literature |
| title_short | Nodal histiocytic disorder in children: report of three cases and review of literature |
| title_sort | nodal histiocytic disorder in children: report of three cases and review of literature |
| url | http://psasir.upm.edu.my/id/eprint/86909/ http://psasir.upm.edu.my/id/eprint/86909/ http://psasir.upm.edu.my/id/eprint/86909/ http://psasir.upm.edu.my/id/eprint/86909/1/Nodal%20histiocytic%20disorder%20in%20children.pdf |