Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment

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Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment

CpG-free pDNA was reported to facilitate sustained transgene expression with minimal inflammation in vivo as compared to CpG-containing pDNA. However, the expression potential and impact of CpG-free pDNA in in vitro model have never been described. Hence, in this study, we analyzed the transgene exp...

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Bibliographic Details
Main Authors:	Habib, Omar, M. Sakri, Rozita, Ghazalli, Nadiah, Chau, De Ming, Ling, King Hwa, Abdullah, Syahril
Format:	Article
Language:	English
Published:	Public Library of Science 2020
Online Access:	http://psasir.upm.edu.my/id/eprint/86578/ http://psasir.upm.edu.my/id/eprint/86578/1/Limited%20expression%20of%20non-integrating%20.pdf

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