Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities
An investigation on the plant of Murraya paniculata, employing extraction of the leaves and stem barks and various chromatographic isolation techniques have been used. The structure of the compounds were elucidated by using spectroscopic techniques such as IR, NMR, MS and also by comparison with...
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| Format: | Thesis |
| Language: | English English |
| Published: |
1998
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| Online Access: | http://psasir.upm.edu.my/id/eprint/8647/ http://psasir.upm.edu.my/id/eprint/8647/1/FSAS_1998_12_A.pdf |
| _version_ | 1848840928261832704 |
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| author | Syed Abd. Azziz, Saripah Salbiah |
| author_facet | Syed Abd. Azziz, Saripah Salbiah |
| author_sort | Syed Abd. Azziz, Saripah Salbiah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | An investigation on the plant of Murraya paniculata, employing
extraction of the leaves and stem barks and various chromatographic isolation
techniques have been used. The structure of the compounds were elucidated by
using spectroscopic techniques such as IR, NMR, MS and also by comparison
with the previous work. Extraction and isolation work of the leaves and stem
barks of Murraya paniculata collected from Lenggong, Perak yielded gardenin E
(28), 3',4',5,5', 7-pentamethoxyflavone (29), 3',4',5,5', 7,8-hexamethoxyflavone
(30), gardenin A (31), sterol mixtures (32), 3',4',5,5',7-pentamethoxyflavanone
(33) and gardenin C (34). Further study on the leaves of the same plant collected from different
location in lpoh, Perak afforded four known coumarins ; auraptene (36),
gleinadiene (37), 5,7-dimethoxy-8-(3-methyl-2-oxo-butyl)coumalin (38) and
toddalenone (39).
The antibacterial and antifungi activities test were also carried out on elUde
PE, CHCh and MeOH extracts of the leaves and stem barks and also towards
pure compounds. This antibacterial activity was tested using the 'disk Diffusion'
method. One gram positive bacteria (Baccilus cereus) and four fungi (Aspergillus
ochraceous, Saccharomyces lipolytica, Saccharomyces cerevisiae dan Candida
lipolytica) were selected for this test. Chloroform extract of Murraya paniculata
gave the highest average zone of inhibition, indicating the degree of its sensitivity.
Meanwhile compound (37) showed moderate degree of toxicity towards the
bacteria. |
| first_indexed | 2025-11-15T07:35:08Z |
| format | Thesis |
| id | upm-8647 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:35:08Z |
| publishDate | 1998 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-86472012-06-11T08:29:53Z http://psasir.upm.edu.my/id/eprint/8647/ Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities Syed Abd. Azziz, Saripah Salbiah An investigation on the plant of Murraya paniculata, employing extraction of the leaves and stem barks and various chromatographic isolation techniques have been used. The structure of the compounds were elucidated by using spectroscopic techniques such as IR, NMR, MS and also by comparison with the previous work. Extraction and isolation work of the leaves and stem barks of Murraya paniculata collected from Lenggong, Perak yielded gardenin E (28), 3',4',5,5', 7-pentamethoxyflavone (29), 3',4',5,5', 7,8-hexamethoxyflavone (30), gardenin A (31), sterol mixtures (32), 3',4',5,5',7-pentamethoxyflavanone (33) and gardenin C (34). Further study on the leaves of the same plant collected from different location in lpoh, Perak afforded four known coumarins ; auraptene (36), gleinadiene (37), 5,7-dimethoxy-8-(3-methyl-2-oxo-butyl)coumalin (38) and toddalenone (39). The antibacterial and antifungi activities test were also carried out on elUde PE, CHCh and MeOH extracts of the leaves and stem barks and also towards pure compounds. This antibacterial activity was tested using the 'disk Diffusion' method. One gram positive bacteria (Baccilus cereus) and four fungi (Aspergillus ochraceous, Saccharomyces lipolytica, Saccharomyces cerevisiae dan Candida lipolytica) were selected for this test. Chloroform extract of Murraya paniculata gave the highest average zone of inhibition, indicating the degree of its sensitivity. Meanwhile compound (37) showed moderate degree of toxicity towards the bacteria. 1998 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/8647/1/FSAS_1998_12_A.pdf Syed Abd. Azziz, Saripah Salbiah (1998) Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities. Masters thesis, Universiti Putra Malaysia. Rutaceae Chemical elements Murraya English |
| spellingShingle | Rutaceae Chemical elements Murraya Syed Abd. Azziz, Saripah Salbiah Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title | Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title_full | Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title_fullStr | Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title_full_unstemmed | Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title_short | Chemical Constituent of Murraya Paniculata (Rutaceae) and Their Biological Activities |
| title_sort | chemical constituent of murraya paniculata (rutaceae) and their biological activities |
| topic | Rutaceae Chemical elements Murraya |
| url | http://psasir.upm.edu.my/id/eprint/8647/ http://psasir.upm.edu.my/id/eprint/8647/1/FSAS_1998_12_A.pdf |