Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2
Pasteurella multocida B:2 is an etiological agent of hemorrhagic septicemia in cattle and buffaloes. It is commonly fatal and considered as one of the most economically important cattle diseases in Southeast Asia. This study describes the pathological changes in the lungs of calves following intra-t...
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia Press
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/8306/ http://psasir.upm.edu.my/id/eprint/8306/1/17%20Pg%20113-117.pdf |
| _version_ | 1848840833679228928 |
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| author | Khin, Myat Nwe Saad, Mohd Zamri Mohamed Mustapha, Noordin |
| author_facet | Khin, Myat Nwe Saad, Mohd Zamri Mohamed Mustapha, Noordin |
| author_sort | Khin, Myat Nwe |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Pasteurella multocida B:2 is an etiological agent of hemorrhagic septicemia in cattle and buffaloes. It is commonly fatal and considered as one of the most economically important cattle diseases in Southeast Asia. This study describes the pathological changes in the lungs of calves following intra-tracheal challenge with wild-type P. multocida B:2. For this purpose, six calves of 8-month old were selected and divided into two groups of 3 calves. Calves of Group 1 were challenged with intra-tracheal 5 ml inoculum containing 109 cfu/ml of wild-type P. multocida B:2, while the calves of Group 2 were similarly administered with PBS. All the challenged calves of Group 1 showed slight dullness and were found to be inactive within 72 hours after inoculation, but none died. Meanwhile, their lungs showed petechiations and patches of acute pneumonia affecting few lobules. Histological examinations revealed the presence of haemorrhages into the alveoli, whereas some sections showed thickened inter-alveolar septa due to congestion and the presence of neutrophils. However, pulmonary oedema was absent. P. multocida B:2 was successfully isolated from all the calves of Group 1. |
| first_indexed | 2025-11-15T07:33:38Z |
| format | Article |
| id | upm-8306 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:33:38Z |
| publishDate | 2010 |
| publisher | Universiti Putra Malaysia Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-83062016-11-22T02:04:49Z http://psasir.upm.edu.my/id/eprint/8306/ Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 Khin, Myat Nwe Saad, Mohd Zamri Mohamed Mustapha, Noordin Pasteurella multocida B:2 is an etiological agent of hemorrhagic septicemia in cattle and buffaloes. It is commonly fatal and considered as one of the most economically important cattle diseases in Southeast Asia. This study describes the pathological changes in the lungs of calves following intra-tracheal challenge with wild-type P. multocida B:2. For this purpose, six calves of 8-month old were selected and divided into two groups of 3 calves. Calves of Group 1 were challenged with intra-tracheal 5 ml inoculum containing 109 cfu/ml of wild-type P. multocida B:2, while the calves of Group 2 were similarly administered with PBS. All the challenged calves of Group 1 showed slight dullness and were found to be inactive within 72 hours after inoculation, but none died. Meanwhile, their lungs showed petechiations and patches of acute pneumonia affecting few lobules. Histological examinations revealed the presence of haemorrhages into the alveoli, whereas some sections showed thickened inter-alveolar septa due to congestion and the presence of neutrophils. However, pulmonary oedema was absent. P. multocida B:2 was successfully isolated from all the calves of Group 1. Universiti Putra Malaysia Press 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/8306/1/17%20Pg%20113-117.pdf Khin, Myat Nwe and Saad, Mohd Zamri and Mohamed Mustapha, Noordin (2010) Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2. Pertanika Journal of Tropical Agricultural Science, 33 (1). pp. 113-117. ISSN 1511-3701; ESSN: 2231-8542 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2033%20(1)%20Feb.%202010/17%20Pg%20113-117.pdf |
| spellingShingle | Khin, Myat Nwe Saad, Mohd Zamri Mohamed Mustapha, Noordin Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title | Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title_full | Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title_fullStr | Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title_full_unstemmed | Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title_short | Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2 |
| title_sort | pathological changes in the lungs of calves following intratracheal exposure to pasteurella multocida b:2 |
| url | http://psasir.upm.edu.my/id/eprint/8306/ http://psasir.upm.edu.my/id/eprint/8306/ http://psasir.upm.edu.my/id/eprint/8306/1/17%20Pg%20113-117.pdf |