Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies
Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/82723/ http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf |
| _version_ | 1848859337709060096 |
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| author | Chin, Liang Lee Veeramani, Sanggeetha Molouki, Aidin Swee, Hua Erin Lim Thomas, Warren Suet, Lin Chia Yusoff, Khatijah |
| author_facet | Chin, Liang Lee Veeramani, Sanggeetha Molouki, Aidin Swee, Hua Erin Lim Thomas, Warren Suet, Lin Chia Yusoff, Khatijah |
| author_sort | Chin, Liang Lee |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest in using viruses to help target therapies to tumour sites. In recent years the evolution of immunotherapy has emphasised the importance of directing the immune system to eliminate tumour cells; we aim to give a state-of-the-art over-view of the diverse viruses that have been investigated as potential oncolytic agents for the treatment of CRC. |
| first_indexed | 2025-11-15T12:27:44Z |
| format | Article |
| id | upm-82723 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:27:44Z |
| publishDate | 2019 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-827232021-06-02T03:41:24Z http://psasir.upm.edu.my/id/eprint/82723/ Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies Chin, Liang Lee Veeramani, Sanggeetha Molouki, Aidin Swee, Hua Erin Lim Thomas, Warren Suet, Lin Chia Yusoff, Khatijah Colorectal cancer (CRC) is one of the most common malignancies. In recent decades, early diagnosis and conventional therapies have resulted in a significant reduction in mortality. However, late stage metastatic disease still has very limited effective treatment options. There is a growing interest in using viruses to help target therapies to tumour sites. In recent years the evolution of immunotherapy has emphasised the importance of directing the immune system to eliminate tumour cells; we aim to give a state-of-the-art over-view of the diverse viruses that have been investigated as potential oncolytic agents for the treatment of CRC. Taylor & Francis 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf Chin, Liang Lee and Veeramani, Sanggeetha and Molouki, Aidin and Swee, Hua Erin Lim and Thomas, Warren and Suet, Lin Chia and Yusoff, Khatijah (2019) Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies. Cancer Investigation, 37 (8). pp. 393-414. ISSN 0735-7907; ESSN 1532-4192 https://www.tandfonline.com/doi/abs/10.1080/07357907.2019.1660887?journalCode=icnv20 10.1080/07357907.2019.1660887. |
| spellingShingle | Chin, Liang Lee Veeramani, Sanggeetha Molouki, Aidin Swee, Hua Erin Lim Thomas, Warren Suet, Lin Chia Yusoff, Khatijah Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title | Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title_full | Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title_fullStr | Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title_full_unstemmed | Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title_short | Virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| title_sort | virotherapy: current trends and future prospects for treatment of colon and rectal malignancies |
| url | http://psasir.upm.edu.my/id/eprint/82723/ http://psasir.upm.edu.my/id/eprint/82723/ http://psasir.upm.edu.my/id/eprint/82723/ http://psasir.upm.edu.my/id/eprint/82723/1/Virotherapy.pdf |