Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties

A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline phenylacetate, choline ricinoleate and choline trichloroacetate. Result obtained from FT-IR, 1H and 13C NMR, mass spectrometry, ther...

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Main Authors: Ahmad, Haslina, Zaharudin, Nurul Syahira, Abdul Majid, Nur Nadia, Jumbri, Khairulazhar, Abdul Rahman, Mohd Basyaruddin
Format: Article
Language:English
Published: Penerbitan Akademia Baru 2019
Online Access:http://psasir.upm.edu.my/id/eprint/82339/
http://psasir.upm.edu.my/id/eprint/82339/1/Synthesis%20and%20characterization.pdf
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author Ahmad, Haslina
Zaharudin, Nurul Syahira
Abdul Majid, Nur Nadia
Jumbri, Khairulazhar
Abdul Rahman, Mohd Basyaruddin
author_facet Ahmad, Haslina
Zaharudin, Nurul Syahira
Abdul Majid, Nur Nadia
Jumbri, Khairulazhar
Abdul Rahman, Mohd Basyaruddin
author_sort Ahmad, Haslina
building UPM Institutional Repository
collection Online Access
description A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline phenylacetate, choline ricinoleate and choline trichloroacetate. Result obtained from FT-IR, 1H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry confirmed the formation of these cholinium-based ILs. These ILs were then tested for their anti-microbial properties towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3).Interestingly, all of the choliniumILs possess excellent antimicrobial activity as good as the standard, Streptomycin. The most significant antimicrobial activity was observed in choline phenylacetate against all seven types of bacteria tested in this study.
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spelling upm-823392020-10-16T20:28:03Z http://psasir.upm.edu.my/id/eprint/82339/ Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties Ahmad, Haslina Zaharudin, Nurul Syahira Abdul Majid, Nur Nadia Jumbri, Khairulazhar Abdul Rahman, Mohd Basyaruddin A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline phenylacetate, choline ricinoleate and choline trichloroacetate. Result obtained from FT-IR, 1H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry confirmed the formation of these cholinium-based ILs. These ILs were then tested for their anti-microbial properties towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3).Interestingly, all of the choliniumILs possess excellent antimicrobial activity as good as the standard, Streptomycin. The most significant antimicrobial activity was observed in choline phenylacetate against all seven types of bacteria tested in this study. Penerbitan Akademia Baru 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/82339/1/Synthesis%20and%20characterization.pdf Ahmad, Haslina and Zaharudin, Nurul Syahira and Abdul Majid, Nur Nadia and Jumbri, Khairulazhar and Abdul Rahman, Mohd Basyaruddin (2019) Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 54 (2). pp. 124-132. ISSN 2289-7879
spellingShingle Ahmad, Haslina
Zaharudin, Nurul Syahira
Abdul Majid, Nur Nadia
Jumbri, Khairulazhar
Abdul Rahman, Mohd Basyaruddin
Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title_full Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title_fullStr Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title_full_unstemmed Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title_short Synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
title_sort synthesis and characterization of new choline-based ionic liquids and their antimicrobial properties
url http://psasir.upm.edu.my/id/eprint/82339/
http://psasir.upm.edu.my/id/eprint/82339/1/Synthesis%20and%20characterization.pdf