Role of polymers as crystal growth inhibitors in coprecipitation via solutionenhanced dispersion by supercritical fluids (SEDS) to improve andrographolide dissolution from standardized Andrographis paniculata extract

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Role of polymers as crystal growth inhibitors in coprecipitation via solutionenhanced dispersion by supercritical fluids (SEDS) to improve andrographolide dissolution from standardized Andrographis paniculata extract

The poor aqueous solubility and dissolution rate of andrographolide in aqueous gastrointestinal fluids often cause low oral bioavailability. In this work, Andrographis paniculata extract containing 16% andrographolide was coprecipitated with Pluronic F127, Eudragit EPO, and Eudragit L100-55 via solu...

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Bibliographic Details
Main Authors:	Lee, Sin Yee, Abdullah, Luqman Chuah, Abdul Rahman, Russly, Abas, Faridah, Chong, Gun Hean
Format:	Article
Language:	English
Published:	Elsevier 2019
Online Access:	http://psasir.upm.edu.my/id/eprint/82045/ http://psasir.upm.edu.my/id/eprint/82045/1/Role%20of%20polymers%20as%20crystal%20growth%20inhibitors%20.pdf

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