REST and neural gene network Dysregulation in iPSC models of Alzheimer’s disease

REST and neural gene network Dysregulation in iPSC models of Alzheimer’s disease

The molecular basis of the earliest neuronal changes that lead to Alzheimer’s disease (AD) is unclear. Here, we analyze neural cells derived from sporadic AD (SAD), APOE4 gene-edited and control induced pluripotent stem cells (iPSCs). We observe major differences in iPSC-derived neural progenitor (N...

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Bibliographic Details
Main Authors: Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan Ta, Su, Susan C., Church, George M., Tsai, Li Huei, Yankner, Bruce A.
Format: Article
Language:English
Published: Cell Press 2019
Online Access:http://psasir.upm.edu.my/id/eprint/82010/
http://psasir.upm.edu.my/id/eprint/82010/1/REST%20and%20neural%20gene%20network%20.pdf

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