Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study
This research study aimed to evaluate metabolites in human skeletal muscles pre- and post-exercise non-invasively via proton magnetic resonance spectroscopy (¹H-MRS). The upper legs of 6 lightly active male subjects underwent imaging pre- and post-exercise via 1.5 T MRI (TR/TE = 3500ms/100ms, FOV =...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Penerbit UTM Press
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/81878/ http://psasir.upm.edu.my/id/eprint/81878/1/Proton%20magnetic%20resonance%20spectroscopy%20%28%C2%B9H-MRS%29%20of%20human%20skeletal%20muscle%20at%201.5%20Tesla.pdf |
| _version_ | 1848859190997549056 |
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| author | Rusli, Nur Syahfinaz Hidayah Zakaria, Faikah Anwar Basha, Farahnaz Ahmad Abdul Razak, Hairil Rashmizal |
| author_facet | Rusli, Nur Syahfinaz Hidayah Zakaria, Faikah Anwar Basha, Farahnaz Ahmad Abdul Razak, Hairil Rashmizal |
| author_sort | Rusli, Nur Syahfinaz Hidayah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This research study aimed to evaluate metabolites in human skeletal muscles pre- and post-exercise non-invasively via proton magnetic resonance spectroscopy (¹H-MRS). The upper legs of 6 lightly active male subjects underwent imaging pre- and post-exercise via 1.5 T MRI (TR/TE = 3500ms/100ms, FOV = 20cm, slice thickness = 6mm) and ¹H-MRS (TR/TE = 2000ms/31ms, VOI = 20mm x 20mm x 35mm). The researchers measured the pre- and post-exercise metabolic readings (NAA, CHO, and Cr metabolites) for the vastus lateralis and semitendinosus muscles. A paired t-test was performed. In the vastus lateralis muscle, NAA, CHO, and Cr metabolites values decreased with no significant difference after the exercise. Similarly, in the semitendinosus muscle, NAA, CHO, and Cr metabolites values were also decreased with CHO (p<0.02) and Cr (p<0.01) showed the significant difference after the exercise. Evaluating human skeletal muscles via ¹H-MRS at 1.5 T is feasible. |
| first_indexed | 2025-11-15T12:25:25Z |
| format | Article |
| id | upm-81878 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:25:25Z |
| publishDate | 2019 |
| publisher | Penerbit UTM Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-818782021-08-12T11:29:30Z http://psasir.upm.edu.my/id/eprint/81878/ Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study Rusli, Nur Syahfinaz Hidayah Zakaria, Faikah Anwar Basha, Farahnaz Ahmad Abdul Razak, Hairil Rashmizal This research study aimed to evaluate metabolites in human skeletal muscles pre- and post-exercise non-invasively via proton magnetic resonance spectroscopy (¹H-MRS). The upper legs of 6 lightly active male subjects underwent imaging pre- and post-exercise via 1.5 T MRI (TR/TE = 3500ms/100ms, FOV = 20cm, slice thickness = 6mm) and ¹H-MRS (TR/TE = 2000ms/31ms, VOI = 20mm x 20mm x 35mm). The researchers measured the pre- and post-exercise metabolic readings (NAA, CHO, and Cr metabolites) for the vastus lateralis and semitendinosus muscles. A paired t-test was performed. In the vastus lateralis muscle, NAA, CHO, and Cr metabolites values decreased with no significant difference after the exercise. Similarly, in the semitendinosus muscle, NAA, CHO, and Cr metabolites values were also decreased with CHO (p<0.02) and Cr (p<0.01) showed the significant difference after the exercise. Evaluating human skeletal muscles via ¹H-MRS at 1.5 T is feasible. Penerbit UTM Press 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81878/1/Proton%20magnetic%20resonance%20spectroscopy%20%28%C2%B9H-MRS%29%20of%20human%20skeletal%20muscle%20at%201.5%20Tesla.pdf Rusli, Nur Syahfinaz Hidayah and Zakaria, Faikah and Anwar Basha, Farahnaz Ahmad and Abdul Razak, Hairil Rashmizal (2019) Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study. Malaysian Journal of Fundamental and Applied Sciences, 15 (6). pp. 772-775. ISSN 2289-5981; ESSN: 2289-599X https://mjfas.utm.my/index.php/mjfas/article/view/1509 |
| spellingShingle | Rusli, Nur Syahfinaz Hidayah Zakaria, Faikah Anwar Basha, Farahnaz Ahmad Abdul Razak, Hairil Rashmizal Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title | Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title_full | Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title_fullStr | Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title_full_unstemmed | Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title_short | Proton magnetic resonance spectroscopy (¹H-MRS) of human skeletal muscle at 1.5 Tesla: potential applications in exercise - a pilot study |
| title_sort | proton magnetic resonance spectroscopy (¹h-mrs) of human skeletal muscle at 1.5 tesla: potential applications in exercise - a pilot study |
| url | http://psasir.upm.edu.my/id/eprint/81878/ http://psasir.upm.edu.my/id/eprint/81878/ http://psasir.upm.edu.my/id/eprint/81878/1/Proton%20magnetic%20resonance%20spectroscopy%20%28%C2%B9H-MRS%29%20of%20human%20skeletal%20muscle%20at%201.5%20Tesla.pdf |