Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vit...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SciCell s.r.o.
2019
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/81741/ http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf |
| _version_ | 1848859169595064320 |
|---|---|
| author | Nordin, Nornasriq Akmal Mohd Zin, Nur Bainun Fazilah, Nurul Farhana Wasoh, Helmi Ariff, Arbakariya Halim, Murni |
| author_facet | Nordin, Nornasriq Akmal Mohd Zin, Nur Bainun Fazilah, Nurul Farhana Wasoh, Helmi Ariff, Arbakariya Halim, Murni |
| author_sort | Nordin, Nornasriq Akmal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vitro qualitative assays showed that both S. alata and S. tora leaf extracts contained bioactive and secondary metabolites components such as tannins, steroids, saponin, terpenoids, glycosides, flavonoids and phenols. The antioxidant activity and capacity test were carried out by conducting free radical of 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and Ferric reduction antioxidant plasma (FRAP) assays. Both assays showed S. tora leaf extract has higher antioxidant capacity than S. alata leaf extract. The efficacy of these leaf extracts were tested against skin pathogens through agar well diffusion method. S. alata extract showed an inhibition zone (1.15 –1.59 mm) against Pseudomonas aeruginosa while S. tora extracts exhibited a strong antimicrobial activity against S. epidermidis (inhibition zone of 12 –16.94 mm) followed by P. aeruginosa (inhibition zone of 1 –1.59 mm). Nonetheless, no inhibition zone was observed for S. aureus by both leaf extracts. The phytochemicals and antioxidant constituents as well as inhibitory potential on skin pathogens possessed by S. alata and S. tora leave highlighted their potential utilization in the development of natural drugs or cosmetics to treat skin related diseases or infections. |
| first_indexed | 2025-11-15T12:25:04Z |
| format | Article |
| id | upm-81741 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:25:04Z |
| publishDate | 2019 |
| publisher | SciCell s.r.o. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-817412022-12-14T07:47:15Z http://psasir.upm.edu.my/id/eprint/81741/ Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections Nordin, Nornasriq Akmal Mohd Zin, Nur Bainun Fazilah, Nurul Farhana Wasoh, Helmi Ariff, Arbakariya Halim, Murni A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vitro qualitative assays showed that both S. alata and S. tora leaf extracts contained bioactive and secondary metabolites components such as tannins, steroids, saponin, terpenoids, glycosides, flavonoids and phenols. The antioxidant activity and capacity test were carried out by conducting free radical of 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and Ferric reduction antioxidant plasma (FRAP) assays. Both assays showed S. tora leaf extract has higher antioxidant capacity than S. alata leaf extract. The efficacy of these leaf extracts were tested against skin pathogens through agar well diffusion method. S. alata extract showed an inhibition zone (1.15 –1.59 mm) against Pseudomonas aeruginosa while S. tora extracts exhibited a strong antimicrobial activity against S. epidermidis (inhibition zone of 12 –16.94 mm) followed by P. aeruginosa (inhibition zone of 1 –1.59 mm). Nonetheless, no inhibition zone was observed for S. aureus by both leaf extracts. The phytochemicals and antioxidant constituents as well as inhibitory potential on skin pathogens possessed by S. alata and S. tora leave highlighted their potential utilization in the development of natural drugs or cosmetics to treat skin related diseases or infections. SciCell s.r.o. 2019-01-23 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf Nordin, Nornasriq Akmal and Mohd Zin, Nur Bainun and Fazilah, Nurul Farhana and Wasoh, Helmi and Ariff, Arbakariya and Halim, Murni (2019) Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections. Bacterial Empire, 2 (1). pp. 19-25. ISSN 2585-9374 https://office.scicell.org/index.php/BE/issue/view/3 10.36547/be.2019.2.1.19-25 |
| spellingShingle | Nordin, Nornasriq Akmal Mohd Zin, Nur Bainun Fazilah, Nurul Farhana Wasoh, Helmi Ariff, Arbakariya Halim, Murni Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title | Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title_full | Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title_fullStr | Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title_full_unstemmed | Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title_short | Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections |
| title_sort | phytochemicals, antioxidant and antimicrobial properties of senna alata and senna tora leaf extracts against bacterial strains causing skin infections |
| url | http://psasir.upm.edu.my/id/eprint/81741/ http://psasir.upm.edu.my/id/eprint/81741/ http://psasir.upm.edu.my/id/eprint/81741/ http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf |