Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases
Many drugs have been designed to treat diseases of the central nervous system (CNS), especially neurodegenerative diseases. However, the presence of tight junctions at the blood-brain barrier has often compromised the efficiency of drug delivery to target sites in the brain. The principles of drug d...
| Main Authors: | Mansor, Nur Izzati, Nordin, Norshariza, Mohamed, Farahidah, Ling, King Hwa, Rosli, Rozita, Hassan, Zurina |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bentham Science
2019
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/81051/ http://psasir.upm.edu.my/id/eprint/81051/1/BLOOD.pdf |
Similar Items
Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases
by: Mansor, Nur Izzati, et al.
Published: (2019)
by: Mansor, Nur Izzati, et al.
Published: (2019)
Modern methods for delivery of drugs across the blood-brain barrier
by: Chen, Yan, et al.
Published: (2012)
by: Chen, Yan, et al.
Published: (2012)
Establishment of horse blood-brain barrier model for the study of drug delivery to the brain
by: Gupta, Gaurav
Published: (2025)
by: Gupta, Gaurav
Published: (2025)
The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes
by: Bates, Jessica
Published: (2025)
by: Bates, Jessica
Published: (2025)
Blood-Brain Barrier on-a-chip model for the study of drug permeability into the brain
by: Whitehouse, Chloe Ann
Published: (2022)
by: Whitehouse, Chloe Ann
Published: (2022)
Drug Permeation across the Blood-Brain Barrier: Applications of Nanotechnology
by: Fakhoury, M., et al.
Published: (2015)
by: Fakhoury, M., et al.
Published: (2015)
Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier
by: Liu, Lihong, et al.
Published: (2008)
by: Liu, Lihong, et al.
Published: (2008)
Development and evaluation of cannabidiol formulations for delivery to the central nervous system to treat neuropathic pain
by: Muresan, Paula Diana
Published: (2022)
by: Muresan, Paula Diana
Published: (2022)
Phytocannabinoids, neuroprotection and the blood-brain barrier
by: Stone, Nicole
Published: (2021)
by: Stone, Nicole
Published: (2021)
Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier
by: Liu, Lihong, et al.
Published: (2008)
by: Liu, Lihong, et al.
Published: (2008)
Blood-brain barrier derangement after electrical brain stimulation
by: Watanabe, Yumiko, et al.
Published: (2017)
by: Watanabe, Yumiko, et al.
Published: (2017)
Construction of in vitro Blood-Brain Barrier (BBB) model using MDCK-1 cell line
by: Mohd Nor, Nor Hafizah, et al.
Published: (2014)
by: Mohd Nor, Nor Hafizah, et al.
Published: (2014)
Nanoformulated antimicrobial agents for central nervous system infections
by: Zhang, S., et al.
Published: (2017)
by: Zhang, S., et al.
Published: (2017)
Central nervous system intravascular lymphoma in a Malaysian.
by: Mohamed Mukari, Shahizon Azura, et al.
Published: (2011)
by: Mohamed Mukari, Shahizon Azura, et al.
Published: (2011)
The effects of "gamat" on nociceptive processing in the
central nervous system
by: Hayati, Asma
Published: (2010)
by: Hayati, Asma
Published: (2010)
The effects of gamat on
nociceptive processing in
the central nervous system
by: Yusof, Mohd Eidham
Published: (2008)
by: Yusof, Mohd Eidham
Published: (2008)
Development of parenteral nanoemulsion systems loaded with carbamazepine for efficient blood-brain barrier crossing in epilepsy treatment
by: Tan, Sim Ling
Published: (2016)
by: Tan, Sim Ling
Published: (2016)
Nanoemulsion-based parenteral drug delivery system of carbamazepine: preparation, characterization, stability evaluation and blood-brain pharmacokinetics
by: Tan, Sim Ling, et al.
Published: (2015)
by: Tan, Sim Ling, et al.
Published: (2015)
Alterations in the endothelial cells of the blood-brain barrier in cerebral malaria
by: Mohd Nasir, Mohd Hamzah, et al.
Published: (2012)
by: Mohd Nasir, Mohd Hamzah, et al.
Published: (2012)
Endocannabinoids modulate human blood-brain barrier permeabilityin vitro
by: Hind, William H., et al.
Published: (2015)
by: Hind, William H., et al.
Published: (2015)
Nipah virus neurotropism: insights into blood-brain barrier disruption
by: Al Obaidi, Mazen M Jamil, et al.
Published: (2024)
by: Al Obaidi, Mazen M Jamil, et al.
Published: (2024)
Synthesis Of Blood-Brain Barrier Permeable Aurones As Modulators Of Microglia
by: Chia, Shi Yi
Published: (2023)
by: Chia, Shi Yi
Published: (2023)
Nose to brain drug delivery: a recent update
by: Chatterjee, Bappaditya
Published: (2017)
by: Chatterjee, Bappaditya
Published: (2017)
Biomaterial-based local drug delivery to brain tumors
by: Rahman, Ruman
Published: (2014)
by: Rahman, Ruman
Published: (2014)
Polymeric Nanoparticles for Brain Drug Delivery - A Review
by: Subashini, Raman, et al.
Published: (2020)
by: Subashini, Raman, et al.
Published: (2020)
Antioxidants attenuate hyperglycaemia-mediated brain
endothelial cell dysfunction and blood–brain barrier
hyperpermeability
by: Allen, C.L., et al.
Published: (2009)
by: Allen, C.L., et al.
Published: (2009)
A neural origin for central nervous system germ cell tumours
by: Tan, Christopher Callum Lee
Published: (2013)
by: Tan, Christopher Callum Lee
Published: (2013)
Characterization of polymeric nanoparticles for treatment of partial injury to the central nervous system
by: Lozic, I., et al.
Published: (2016)
by: Lozic, I., et al.
Published: (2016)
Higher fish consumption and lower risk of central nervous system demyelination
by: Black, Lucinda, et al.
Published: (2020)
by: Black, Lucinda, et al.
Published: (2020)
Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: a review
by: Mustapha, Saeed, et al.
Published: (2024)
by: Mustapha, Saeed, et al.
Published: (2024)
Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2014)
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2014)
The effect of diesel exhaust emission on blood brain barrier integrity and function
by: Heidari Nejad, Sayeh
Published: (2014)
by: Heidari Nejad, Sayeh
Published: (2014)
Prediction of blood-brain barrier permeability of compounds by machine learning algorithms
by: Feng, Tan wei, et al.
Published: (2024)
by: Feng, Tan wei, et al.
Published: (2024)
Understanding the mechanisms underlying the disruption of the blood–brain barrier in parasitic infections
by: Jamil Al‐Obaidi, Mazen M., et al.
Published: (2024)
by: Jamil Al‐Obaidi, Mazen M., et al.
Published: (2024)
Targeted delivery of BDNF-loaded poly (lactide-co-glycolide) nanoparticle to the brain: penetration through blood brain barrier and neuroprotective effect in stroke / Siti Norsyafika Kamarudin
by: Kamarudin, Siti Norsyafika
Published: (2019)
by: Kamarudin, Siti Norsyafika
Published: (2019)
Cationic supramolecular hydrogels for overcoming the
skin barrier in drug delivery
by: Limon, David, et al.
Published: (2017)
by: Limon, David, et al.
Published: (2017)
Exercise training improved blood flow velocity and autonomic nervous activity
by: Noor Azmi, Azran Azhim, et al.
Published: (2006)
by: Noor Azmi, Azran Azhim, et al.
Published: (2006)
Autonomic and central nervous system correlates of cognitive control training for attentional disorders
by: Waitt, Alice Emily
Published: (2022)
by: Waitt, Alice Emily
Published: (2022)
Changes in subtypes of Ca microdomains following partial injury to the central nervous system
by: Lozic, I., et al.
Published: (2014)
by: Lozic, I., et al.
Published: (2014)
Is cerebral small vessel disease a central nervous system interstitial fluidopathy?
by: Abdul Hamid, Hafizah, et al.
Published: (2024)
by: Abdul Hamid, Hafizah, et al.
Published: (2024)
Similar Items
-
Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases
by: Mansor, Nur Izzati, et al.
Published: (2019) -
Modern methods for delivery of drugs across the blood-brain barrier
by: Chen, Yan, et al.
Published: (2012) -
Establishment of horse blood-brain barrier model for the study of drug delivery to the brain
by: Gupta, Gaurav
Published: (2025) -
The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes
by: Bates, Jessica
Published: (2025) -
Blood-Brain Barrier on-a-chip model for the study of drug permeability into the brain
by: Whitehouse, Chloe Ann
Published: (2022)