Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved...
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| Format: | Article |
| Language: | English |
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Taylor & Francis
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/80981/ http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf |
| _version_ | 1848858995397230592 |
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| author | Yee, Joanne Kam Wai Abas, Faridah Hussain, Norhayati Mirhosseini, Hamed |
| author_facet | Yee, Joanne Kam Wai Abas, Faridah Hussain, Norhayati Mirhosseini, Hamed |
| author_sort | Yee, Joanne Kam Wai |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved 3× higher in total phenolic content in the leaf extract compared to ASE. DPPH radical scavenging activity was 4.6× higher in leaf extract from ASE. No significant differences reported in ferric reducing power, and total flavonoid content of the leaf extract between the two methods. Cytotoxicity via MTT assay demonstrated no significant differences in cell viability upon exposure to the leaf extract from both methods. This suggested that they were appropriate in producing Durio zibethinus M. leaf extract for end use application in food related product. Both ensured similar level of safety in Durio zibethinus M. leaf extract as a new potential ingredient for the food industry. |
| first_indexed | 2025-11-15T12:22:18Z |
| format | Article |
| id | upm-80981 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:22:18Z |
| publishDate | 2019 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-809812020-10-14T20:54:12Z http://psasir.upm.edu.my/id/eprint/80981/ Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity Yee, Joanne Kam Wai Abas, Faridah Hussain, Norhayati Mirhosseini, Hamed The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved 3× higher in total phenolic content in the leaf extract compared to ASE. DPPH radical scavenging activity was 4.6× higher in leaf extract from ASE. No significant differences reported in ferric reducing power, and total flavonoid content of the leaf extract between the two methods. Cytotoxicity via MTT assay demonstrated no significant differences in cell viability upon exposure to the leaf extract from both methods. This suggested that they were appropriate in producing Durio zibethinus M. leaf extract for end use application in food related product. Both ensured similar level of safety in Durio zibethinus M. leaf extract as a new potential ingredient for the food industry. Taylor & Francis 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf Yee, Joanne Kam Wai and Abas, Faridah and Hussain, Norhayati and Mirhosseini, Hamed (2019) Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity. Natural Product Research, 34 (13). pp. 1937-1941. ISSN 1478-6419; ESSN: 1478-6427 https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1564296?journalCode=gnpl20 10.1080/14786419.2018.1564296 |
| spellingShingle | Yee, Joanne Kam Wai Abas, Faridah Hussain, Norhayati Mirhosseini, Hamed Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title | Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title_full | Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title_fullStr | Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title_full_unstemmed | Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title_short | Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| title_sort | comparison of crude extract from durio zibethinus m. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity |
| url | http://psasir.upm.edu.my/id/eprint/80981/ http://psasir.upm.edu.my/id/eprint/80981/ http://psasir.upm.edu.my/id/eprint/80981/ http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf |