The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital

Introduction: An arteriovenous malformation (AVM) is an abnormal collection of blood vessels in which arterial blood flows directly into the draining vein without the normal interposed capillaries. The Spetzler-Martin grading system has been widely accepted worldwide to estimate the pretreatment...

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Main Authors: Al-Edrus, Sharifah Aishah, Suhaimi, Siti Norziela, Abdul Rahman, Noor Azman, Abd Latif, Ahmad Zubaidi, Muda, Ahmad Sobri
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2010
Online Access:http://psasir.upm.edu.my/id/eprint/8094/
http://psasir.upm.edu.my/id/eprint/8094/1/Spetzler91-99%28edSP%29.pdf
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author Al-Edrus, Sharifah Aishah
Suhaimi, Siti Norziela
Abdul Rahman, Noor Azman
Abd Latif, Ahmad Zubaidi
Muda, Ahmad Sobri
author_facet Al-Edrus, Sharifah Aishah
Suhaimi, Siti Norziela
Abdul Rahman, Noor Azman
Abd Latif, Ahmad Zubaidi
Muda, Ahmad Sobri
author_sort Al-Edrus, Sharifah Aishah
building UPM Institutional Repository
collection Online Access
description Introduction: An arteriovenous malformation (AVM) is an abnormal collection of blood vessels in which arterial blood flows directly into the draining vein without the normal interposed capillaries. The Spetzler-Martin grading system has been widely accepted worldwide to estimate the pretreatment risks and predict the outcome of patients with intracranial AVM. In Malaysia, we still do not have the baseline data of this grading system. Methods: A total of 33 patients from a tertiary referral hospital diagnosed with intracranial AVM based on neuroimaging findings over a 4-year period were studied. Medical records were traced and neuroimaging findings were analysed. The AVMs were graded according to the Spetzler-Martin grading system and Fisher’s exact test was used to assess statistical difference between the grades of the AVM and management plan for the patients. Results: Four patients were graded as Grade 1, 9 patients as Grade II, 10 patients as Grade III, 6 patients as Grade IV and 4 patients as Grade V. Ten patients were treated conservatively; six patients underwent surgery and embolisation respectively. Four patients underwent radiosurgery and a combination of embolisation while surgery and radiosurgery were given to 5 patients and 2 patients respectively. Statistically significant difference (p=0.016) was found between the Spetzler-Martin grading system and the management of intracranial AVMs. Conclusion: The management decision was not made based on the grading of the AVMs. It is recommended that all AVM patients be routinely graded according to this system prior to treatment. Keywords: Intracranial arteriovenous malformation,
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spelling upm-80942015-09-08T01:36:51Z http://psasir.upm.edu.my/id/eprint/8094/ The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital Al-Edrus, Sharifah Aishah Suhaimi, Siti Norziela Abdul Rahman, Noor Azman Abd Latif, Ahmad Zubaidi Muda, Ahmad Sobri Introduction: An arteriovenous malformation (AVM) is an abnormal collection of blood vessels in which arterial blood flows directly into the draining vein without the normal interposed capillaries. The Spetzler-Martin grading system has been widely accepted worldwide to estimate the pretreatment risks and predict the outcome of patients with intracranial AVM. In Malaysia, we still do not have the baseline data of this grading system. Methods: A total of 33 patients from a tertiary referral hospital diagnosed with intracranial AVM based on neuroimaging findings over a 4-year period were studied. Medical records were traced and neuroimaging findings were analysed. The AVMs were graded according to the Spetzler-Martin grading system and Fisher’s exact test was used to assess statistical difference between the grades of the AVM and management plan for the patients. Results: Four patients were graded as Grade 1, 9 patients as Grade II, 10 patients as Grade III, 6 patients as Grade IV and 4 patients as Grade V. Ten patients were treated conservatively; six patients underwent surgery and embolisation respectively. Four patients underwent radiosurgery and a combination of embolisation while surgery and radiosurgery were given to 5 patients and 2 patients respectively. Statistically significant difference (p=0.016) was found between the Spetzler-Martin grading system and the management of intracranial AVMs. Conclusion: The management decision was not made based on the grading of the AVMs. It is recommended that all AVM patients be routinely graded according to this system prior to treatment. Keywords: Intracranial arteriovenous malformation, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/8094/1/Spetzler91-99%28edSP%29.pdf Al-Edrus, Sharifah Aishah and Suhaimi, Siti Norziela and Abdul Rahman, Noor Azman and Abd Latif, Ahmad Zubaidi and Muda, Ahmad Sobri (2010) The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital. Malaysian Journal of Medicine and Health Sciences, 6 (1). pp. 91-99. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2010V06N1_OP06.pdf
spellingShingle Al-Edrus, Sharifah Aishah
Suhaimi, Siti Norziela
Abdul Rahman, Noor Azman
Abd Latif, Ahmad Zubaidi
Muda, Ahmad Sobri
The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title_full The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title_fullStr The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title_full_unstemmed The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title_short The Spetzler-Martin grading system and management of patients with intracranial Arteriovenous malformation in a tertiary referral hospital
title_sort spetzler-martin grading system and management of patients with intracranial arteriovenous malformation in a tertiary referral hospital
url http://psasir.upm.edu.my/id/eprint/8094/
http://psasir.upm.edu.my/id/eprint/8094/
http://psasir.upm.edu.my/id/eprint/8094/1/Spetzler91-99%28edSP%29.pdf