An inhibited dopamine synthesizing cell model of AADC deficiency
Introduction: Aromatic L-amino acid decarboxylase deficiency (AADC) is a rare autosomal recessive pediatric neurotransmitter disease. To date it remains poorly understood mainly due to an absence of a disease model. The dopaminergic neuroblastoma cell SH-SY5Y was chosen to develop our AADC deficienc...
| Main Authors: | Khalid, Melati, Mohd Moklas, Mohamad Aris |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Biome Scientia
2019
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/80606/ http://psasir.upm.edu.my/id/eprint/80606/1/AADC.pdf |
Similar Items
A cellular model for aromatic L-amino acid decarboxylase deficiency and neurotransmitter analysis of available therapeutics using a neuroblastoma cell culture
by: Khalid, Melati
Published: (2015)
by: Khalid, Melati
Published: (2015)
Interrelations of pleasure deficiency, dopamine high secretion and overconsumption of saccharin on sprague dawley rats
by: Zakaria, Toumi
Published: (2020)
by: Zakaria, Toumi
Published: (2020)
Dopamine D1 receptor involvement in latent inhibition and overshadowing
by: Nelson, Andrew J.D., et al.
Published: (2012)
by: Nelson, Andrew J.D., et al.
Published: (2012)
Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing
by: Nelson, Andrew J.D., et al.
Published: (2012)
by: Nelson, Andrew J.D., et al.
Published: (2012)
Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition
by: Nelson, Andrew J.D., et al.
Published: (2011)
by: Nelson, Andrew J.D., et al.
Published: (2011)
D-amphetamine and antipsychotic drug effects on latent
inhibition in mice lacking dopamine D2 receptors
by: Bay-Richter, C., et al.
Published: (2013)
by: Bay-Richter, C., et al.
Published: (2013)
Potentiation of latent inhibition by haloperidol and clozapine is attenuated in Dopamine D2 receptor (Drd-2) deficient mice: Do antipsychotics influence learning to ignore irrelevant stimuli via both Drd-2 and non-Drd-2 mechanisms?
by: O'Callaghan, M.J., et al.
Published: (2014)
by: O'Callaghan, M.J., et al.
Published: (2014)
In-situ formation of electron acceptor to inhibit charge separation of photo-electrochemical sensor of dopamine-based CdS/Au/GQDs
by: Ibrahim, Izwaharyanie, et al.
Published: (2020)
by: Ibrahim, Izwaharyanie, et al.
Published: (2020)
On-Demand Dopamine Receptor Activation via Photoresponsive Nanoparticle-Dopamine Conjugates with an Emphasis on Parkinson’s Disease
by: Alghamdi, Hajar
Published: (2024)
by: Alghamdi, Hajar
Published: (2024)
Toxoplasma gondii induced cognitive impairment in rats via dysregulation of dopamine receptors and indoleamine 2,3 dioxygenase
by: Wana, Mohammed Nasiru, et al.
Published: (2023)
by: Wana, Mohammed Nasiru, et al.
Published: (2023)
Ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells
by: Sultana, Rebeka, et al.
Published: (2013)
by: Sultana, Rebeka, et al.
Published: (2013)
Recent advances in electrochemical and optical sensing of dopamine
by: Eddin, Faten Bashar Kamal, et al.
Published: (2020)
by: Eddin, Faten Bashar Kamal, et al.
Published: (2020)
The dopamine D3-preferring D2/D3 dopamine receptor partial agonist, cariprazine, reverses behavioral changes in a rat neurodevelopmental model for schizophrenia
by: Watson, David J.G., et al.
Published: (2016)
by: Watson, David J.G., et al.
Published: (2016)
Prevalence of anaemia, iron deficiency, iron deficiency anaemia and risk factors for iron deficiency in kelantanese children
by: Ali Shibramulisi, Siti Noor
Published: (2001)
by: Ali Shibramulisi, Siti Noor
Published: (2001)
Prevalence of anaemia, iron deficiency, iron deficiency anaemia and risk factors for iron deficiency in Kelantanese children
by: Ali Shibramulisi, Siti Noor
Published: (2001)
by: Ali Shibramulisi, Siti Noor
Published: (2001)
CD19 Deficient B Cell Abnormality and Selective IgM Deficiency in a Malay Child. A Case Report.
by: Nohl, L.M., et al.
Published: (2012)
by: Nohl, L.M., et al.
Published: (2012)
Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
by: Mohd Azli, Nor Farhana Waheeda
Published: (2018)
by: Mohd Azli, Nor Farhana Waheeda
Published: (2018)
Determination of agonist intrinsic efficacies at the dopamine D2 receptor
by: Stott, Lisa Alice
Published: (2017)
by: Stott, Lisa Alice
Published: (2017)
Kinetic studies of dopamine D2 receptor molecular pharmacology
by: Keen, Alastair C.
Published: (2021)
by: Keen, Alastair C.
Published: (2021)
The causal role between phasic midbrain dopamine signals and learning
by: Aquili, Luca *
Published: (2014)
by: Aquili, Luca *
Published: (2014)
Review-electrochemical detection of uric acid, dopamine and ascorbic acid
by: Tukimin, Nurulkhalilah, et al.
Published: (2018)
by: Tukimin, Nurulkhalilah, et al.
Published: (2018)
Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease
by: Reyes, S., et al.
Published: (2013)
by: Reyes, S., et al.
Published: (2013)
Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics
by: Fyfe, Tim
Published: (2019)
by: Fyfe, Tim
Published: (2019)
2, 4, 6,-trihydroxy- 3-geranylacetophenone (tHGA) inhibits newly synthesized mediators release in IgE-mediated mast cell degranulation
by: Tan, Ji Wei, et al.
Published: (2015)
by: Tan, Ji Wei, et al.
Published: (2015)
Development of plasmonic-based sensor for highly sensitive and selective detection of dopamine
by: Kamal Eddin, Faten Bashar, et al.
Published: (2023)
by: Kamal Eddin, Faten Bashar, et al.
Published: (2023)
Cytotoxicity and inhibition of nitric oxide syntheses in LPS induced macrophage by water soluble fractions of brown seaweed
by: Monsur, Hammed Ademola, et al.
Published: (2014)
by: Monsur, Hammed Ademola, et al.
Published: (2014)
A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse
by: Fu, Y., et al.
Published: (2012)
by: Fu, Y., et al.
Published: (2012)
Selenium deficiency increased the hypertensive effect of an omega-3 fatty acid deficient diet.
by: Ahmad Hafandi,, et al.
Published: (2014)
by: Ahmad Hafandi,, et al.
Published: (2014)
New modified mesoporous silica nanoparticles with bimetallic Ni-Zr for electroanalytical detection of dopamine
by: Mohamed Roduan, Mohamad Rafizie Aiman, et al.
Published: (2022)
by: Mohamed Roduan, Mohamad Rafizie Aiman, et al.
Published: (2022)
Hematite nanoparticles-modified electrode based electrochemical sensing platform for dopamine
by: Kamali, Khosro Zangeneh, et al.
Published: (2014)
by: Kamali, Khosro Zangeneh, et al.
Published: (2014)
Dopamine 2 Receptor Genes Are Associated with Raised Blood Glucose in Schizophrenia
by: Lawford, B., et al.
Published: (2016)
by: Lawford, B., et al.
Published: (2016)
Menhaden fish oil attenuates postpartum depression in rat model via inhibition of NLRP3-inflammasome driven inflammatory pathway
by: Abdul Aziz, Nurul Uyun, et al.
Published: (2021)
by: Abdul Aziz, Nurul Uyun, et al.
Published: (2021)
Controlled dopamine (D1) receptor stimulation using photo-responsive substrates
by: Rajput, Sunil
Published: (2019)
by: Rajput, Sunil
Published: (2019)
Exploration of polymer-based nanocomposites as dopamine electrochemical sensors / Chang Yeet Hoong
by: Chang , Yeet Hoong
Published: (2022)
by: Chang , Yeet Hoong
Published: (2022)
Dietary repletion with ω3 fatty acid or with COX inhibition reverses cognitive effects in F3 ω3 fatty-acid–deficient mice
by: Ahmad, Hafandi, et al.
Published: (2014)
by: Ahmad, Hafandi, et al.
Published: (2014)
Methods and compositions for inhibiting cancer cell growth
by: Mohamed, Suhaila, et al.
Published: (2014)
by: Mohamed, Suhaila, et al.
Published: (2014)
The clinical significance of immunoglobulin A deficiency
by: Abdul Latiff, Amir Hamzah, et al.
Published: (2007)
by: Abdul Latiff, Amir Hamzah, et al.
Published: (2007)
Lipid Accumulation in Dysferlin-Deficient Muscles
by: Grounds, M., et al.
Published: (2014)
by: Grounds, M., et al.
Published: (2014)
Thiamine deficiency in diabetes – is diet relevant?
by: Vindedzis, S., et al.
Published: (2008)
by: Vindedzis, S., et al.
Published: (2008)
Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition
by: Elmorsy, Ekramy, et al.
Published: (2017)
by: Elmorsy, Ekramy, et al.
Published: (2017)
Similar Items
-
A cellular model for aromatic L-amino acid decarboxylase deficiency and neurotransmitter analysis of available therapeutics using a neuroblastoma cell culture
by: Khalid, Melati
Published: (2015) -
Interrelations of pleasure deficiency, dopamine high secretion and overconsumption of saccharin on sprague dawley rats
by: Zakaria, Toumi
Published: (2020) -
Dopamine D1 receptor involvement in latent inhibition and overshadowing
by: Nelson, Andrew J.D., et al.
Published: (2012) -
Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing
by: Nelson, Andrew J.D., et al.
Published: (2012) -
Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition
by: Nelson, Andrew J.D., et al.
Published: (2011)