Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21
Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their microenvironment, communicating with and reprogramming surrounding cells, resulting in enhanced angiogenesis, immune su...
| Main Authors: | Abels, Erik R., Maas, Sybren L. N., Nieland, Lisa, Wei, Zhiyun, Cheah, Pike See, Tai, Eric, Kolsteeg, Christy-Joy, Dusoswa, Sophie A., Ting, David T., Hickman, Suzanne, El Khoury, Joseph, Krichevsky, Anna M., Broekman, Marike L. D., Breakefield, Xandra O. |
|---|---|
| Format: | Article |
| Published: |
Cell Press
2019
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/79998/ |
Similar Items
CRISPR-Cas knockout of miR21 reduces glioma growth
by: Nieland, Lisa, et al.
Published: (2022)
by: Nieland, Lisa, et al.
Published: (2022)
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells
by: Lucero, Rocco, et al.
Published: (2020)
by: Lucero, Rocco, et al.
Published: (2020)
Targeting DNA repair for personalisation of glioblastoma therapy
by: Perry, Christina Joy
Published: (2016)
by: Perry, Christina Joy
Published: (2016)
Immunoregulation of microglia with tocotrienols
by: Tan, Shi Wei
Published: (2012)
by: Tan, Shi Wei
Published: (2012)
Identification of oocyte reprogramming factors and mechanisms
by: Mola, Choulia
Published: (2017)
by: Mola, Choulia
Published: (2017)
Current techniques in reprogramming cell potency
by: Romli, Firdaus, et al.
Published: (2013)
by: Romli, Firdaus, et al.
Published: (2013)
Role of microglia in embryonic neurogenesis
by: Tong, Chih Kong, et al.
Published: (2016)
by: Tong, Chih Kong, et al.
Published: (2016)
Age-related changes in the phenotype of microglia
by: Imraish, Amer
Published: (2018)
by: Imraish, Amer
Published: (2018)
Early epigenetic reprogramming in fertilized, cloned, and parthenogenetic embryos
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)
Reprogramming of the mouse Nanog gene in amphibian oocyte extracts
by: Bereketoğlu, Sidar
Published: (2016)
by: Bereketoğlu, Sidar
Published: (2016)
Mesenchymal stem cell-mediated immunomodulation of microglia
by: Jose, Shinsmon
Published: (2013)
by: Jose, Shinsmon
Published: (2013)
Immunomodulatory potential of mesenchymal stem cells on microglia
by: Vidyadaran, Sharmili, et al.
Published: (2012)
by: Vidyadaran, Sharmili, et al.
Published: (2012)
Advancements in reprogramming strategies for the generation of induced pluripotent stem cells.
by: Lai, Mei I., et al.
Published: (2011)
by: Lai, Mei I., et al.
Published: (2011)
Expression of circulating miR-101 and miR-744 in nasopharyngeal carcinoma and their performance as diagnostic biomarkers
by: Ahmad, Azmir, et al.
Published: (2018)
by: Ahmad, Azmir, et al.
Published: (2018)
Differential expression of miR-101 and miR-744 in nasopharyngeal carcinoma in Pahang state of Malaysia
by: Ahmad, Azmir, et al.
Published: (2019)
by: Ahmad, Azmir, et al.
Published: (2019)
Enhanced dendritic cell immunotherapy to treat glioblastoma
by: Adhikaree, Jason
Published: (2019)
by: Adhikaree, Jason
Published: (2019)
Recent advances in the therapeutic strategies of glioblastoma multiforme
by: Aldoghachi, Asraa Faris, et al.
Published: (2022)
by: Aldoghachi, Asraa Faris, et al.
Published: (2022)
Novel Methods for microglia segmentation, feature extraction and classification
by: Ding, Yuchun, et al.
Published: (2016)
by: Ding, Yuchun, et al.
Published: (2016)
Mesenchymal stem cell and microglia crosstalk in an inflammatory paradigm
by: Rahmat, Muhammad Zul'atfi
Published: (2013)
by: Rahmat, Muhammad Zul'atfi
Published: (2013)
In vitro modulatory effects of microglia on neuroepithelial cell neurodifferentiation
by: Tong, Chih Kong
Published: (2017)
by: Tong, Chih Kong
Published: (2017)
Expression and association of miR-181a and miR-663 and their target genes in head and neck cancer
by: Masood, Yaghma
Published: (2018)
by: Masood, Yaghma
Published: (2018)
Gene regulatory network and epigenetic reprogramming of pig primordial germ cells
by: Zhang, Haixin
Published: (2016)
by: Zhang, Haixin
Published: (2016)
Production of lentiviral vector with polycistronic transcripts for reprogramming of mouse fibroblast cells
by: Al Abbar, Akram, et al.
Published: (2018)
by: Al Abbar, Akram, et al.
Published: (2018)
Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance
by: Hirpara, J., et al.
Published: (2019)
by: Hirpara, J., et al.
Published: (2019)
Spatiotemporal expression and molecular characterization of miR-344b and miR-344c in the developing mouse brain
by: Leong, Jia Wen, et al.
Published: (2016)
by: Leong, Jia Wen, et al.
Published: (2016)
Spatiotemporal expression and molecular characterisation of miR-344b and miR-344c in developing mouse brain
by: Leong, Angeline Jia Wen
Published: (2015)
by: Leong, Angeline Jia Wen
Published: (2015)
Chlorotoxin as a Drug Delivery System to treat Glioblastoma
by: Fawzy, Ahmed Faadil
Published: (2021)
by: Fawzy, Ahmed Faadil
Published: (2021)
Development of an EGFR-targeted Drug Delivery System for Glioblastoma
by: Zhao, Zi-Ruo
Published: (2023)
by: Zhao, Zi-Ruo
Published: (2023)
MicroRNA regulation of glycolytic metabolism in glioblastoma multiforme
by: Alfardus, Huda, et al.
Published: (2017)
by: Alfardus, Huda, et al.
Published: (2017)
Primary Airway Epithelial Cells That Are Conditionally Reprogrammed Maintain Lineage, Phenotypic And Functional Characteristics
by: Kicic, Anthony, et al.
Published: (2016)
by: Kicic, Anthony, et al.
Published: (2016)
Targeting Microglia as a Therapeutic Approach to Treat Neuroinflammatory Disorders
by: Almalki, Masi
Published: (2025)
by: Almalki, Masi
Published: (2025)
Palm tocotrienols reduce lipopolysaccharide-stimulated inflammatory responses of microglia
by: Tan, Shi Wei, et al.
Published: (2016)
by: Tan, Shi Wei, et al.
Published: (2016)
A three-dimensional culture model of lipopolysaccharide-activated microglia
by: Haw, Tatt Yhew
Published: (2015)
by: Haw, Tatt Yhew
Published: (2015)
Synthesis Of Blood-Brain Barrier Permeable Aurones As Modulators Of Microglia
by: Chia, Shi Yi
Published: (2023)
by: Chia, Shi Yi
Published: (2023)
Study of mixing in Miniaturized Intensified Reactor (MIR)
by: Gopinathan, Subramaniam
Published: (2017)
by: Gopinathan, Subramaniam
Published: (2017)
Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer
by: German, Sergio D., et al.
Published: (2015)
by: German, Sergio D., et al.
Published: (2015)
Induced pluripotent stem cells: reprogramming platforms and applications in cell replacement therapy
by: Al Abbar, Akram, et al.
Published: (2020)
by: Al Abbar, Akram, et al.
Published: (2020)
Conditionally reprogrammed primary airway epithelial cells successfully maintain lineage, phenotypic and functional characteristics
by: Martinovich, K., et al.
Published: (2015)
by: Martinovich, K., et al.
Published: (2015)
Spatiotemporal expression profiling and molecular characterisation of miR-344b and miR-344c in the developing mouse brain
by: Leong, Jia Wen, et al.
Published: (2015)
by: Leong, Jia Wen, et al.
Published: (2015)
Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme
by: Schiefer, L., et al.
Published: (2014)
by: Schiefer, L., et al.
Published: (2014)
Similar Items
-
CRISPR-Cas knockout of miR21 reduces glioma growth
by: Nieland, Lisa, et al.
Published: (2022) -
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells
by: Lucero, Rocco, et al.
Published: (2020) -
Targeting DNA repair for personalisation of glioblastoma therapy
by: Perry, Christina Joy
Published: (2016) -
Immunoregulation of microglia with tocotrienols
by: Tan, Shi Wei
Published: (2012) -
Identification of oocyte reprogramming factors and mechanisms
by: Mola, Choulia
Published: (2017)