Evaluation of a recombinant Newcastle disease virus expressing human IL12 against human breast cancer

QR Code

Evaluation of a recombinant Newcastle disease virus expressing human IL12 against human breast cancer

The Newcastle disease virus (NDV) strain AF2240 is an avian avulavirus that has been demonstrated to possess oncolytic activity against cancer cells. However, to illicit a greater anti-cancer immune response, it is believed that the incorporation of immunostimulatory genes such as IL12 into a recomb...

Full description

Bibliographic Details
Main Authors:	Mohamed Amin, Zahiah, Che Ani, Muhamad Alhapis, Tan, Sheau Wei, Yeap, Swee Keong, Mohammed Alitheen, Noorjahan Banu, Syed Najmuddin, Syed Umar Faruq, Kalyanasundram, Jeevanathan, Chan, Soon Choy, Veerakumarasivam, Abhimanyu, Chia, Suet Lin, Yusoff, Khatijah
Format:	Article
Published:	Nature Publishing Group 2019
Online Access:	http://psasir.upm.edu.my/id/eprint/79739/

Similar Items

Oncolytic effects of the recombinant newcastle disease virus, rAF-IL12, against colon cancer cells in vitro and in tumor-challenged NCr-foxn1nu nude mice
by: Syed Najmuddin, Syed Umar Faruq, et al.
Published: (2020)

Engineering recombinant newcastle disease virus with pro-apoptotic gene to enhance oncolysis in selected colorectal cancer cells
by: Kalyanasundram, Jeevanathan
Published: (2020)

Efficacy of recombinant Newcastle disease virus, RAF-IL12 as a potential therapeutic cancer vaccine in CT26 and HT29 cancer cell line and in mouse model
by: Syed Najmuddin, Syed Umar Faruq
Published: (2019)

Newcastle disease virus strain AF2240 as an oncolytic virus: a review
by: Kalyanasundram J, Jeevanathan, et al.
Published: (2018)

Safety and efficacy of recombinant newcastle disease virus expressing human interleukin-12 as a potential vaccine in breast cancer
by: Mohamed Amin, Zahiah
Published: (2019)

Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2010)

Persistent Newcastle disease virus infection in bladder cancer cells is associated with putative pro-survival and anti-viral transcriptomic changes
by: Chan, Lee Chin, et al.
Published: (2021)

Immunomodulatory effects of Newcastle disease virus AF2240 strain on human peripheral blood mononuclear cells
by: Lam, Han Yuen, et al.
Published: (2014)

An improved method for the rescue of of recombinant Newcastle disease virus
by: Cheow, Pheik Sheen, et al.
Published: (2019)

Development of a recombinant non-replicating Newcastle disease virus
by: Cheow, Pheik-Sheen, et al.
Published: (2024)

Construction and characterization of a Lactococcus lactis in-trans surface display system harboring murine glycosylated tyrosinase related protein-2
by: Kalyanasundram, Jeevanathan
Published: (2015)

Recovery of a Malaysian recombinant Newcastle disease virus strain
by: Kavitha, Murulitharan, et al.
Published: (2013)

Safety and clinical usage of Newcastle disease virus in cancer therapy.
by: Lam, Han Yuen, et al.
Published: (2011)

The recombinant nucleocapsid protein of Newcastle disease virus produced in yeast.
by: Jahanshiri, Fatemeh, et al.
Published: (2010)

Autophagy inhibition suppresses Newcastle disease virus-induced cell death by inhibiting viral replication in human breast cancer cells
by: Rozilah, Megat Irfan, et al.
Published: (2024)

Newcastle diseases virus strain V4UPM displayed oncolytic ability against experimental human malignant glioma
by: Zulkifli, M. M., et al.
Published: (2009)

Antibody and T cell responses induced in chickens immunized with avian influenza virus N1 and NP DNA vaccine with chicken IL-15 and IL-18.
by: Lim, Kian Lam, et al.
Published: (2013)

Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus
by: Teo, Kristeen Ye Wen, et al.
Published: (2013)

Recombinant human serum albumin
by: Chuang, Victor, et al.
Published: (2007)

Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-mb231 breast cancer cells
by: Radwan, Esam M., et al.
Published: (2016)

Thermostability of the Recombinant Haemagglutinin-Neuraminidase Glycoproteins of Newcastle Disease Virus
by: Tang, Yik Kiong
Published: (2003)

Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus
by: Rasoli, Mehdi, et al.
Published: (2014)

Development of a T7 RNA polymerase expressing cell line using lentivirus vectors for the recovery of recombinant Newcastle disease virus
by: Yeong, Ming Yue, et al.
Published: (2021)

Viral persistence in colorectal cancer cells infected by Newcastle disease virus
by: Chia, Suet Lin, et al.
Published: (2014)

Immunogenic properties of recombinant ectodomain of Newcastle disease virus hemagglutinin-neuraminidase protein expressed in Escherichia coli.
by: Wong, Sing King, et al.
Published: (2009)

Cloning of human- interleukin-12 into pJET cloning vector for anti-cancer vaccine development
by: Che Ani, Muhamad Alhapis
Published: (2015)

Comparative study of antioxidant level and activity from leaf extracts of Annona muricata Linn obtained from different locations
by: Syed Najmuddin, Syed Umar Faruq, et al.
Published: (2017)

Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-lauryl sarcosine)
by: Mustafa, Anhar Danial, et al.
Published: (2019)

Verification of H5 and IL-15 gene integrations in recombinant fowlpox viruses
by: Nor Majid, Nadzreeq, et al.
Published: (2015)

Cytotoxicity, regulation of apoptotic and anti-apoptotic gene expression by IL-27 in MCF-7 and MDA-MB-231 breast cancer cell lines
by: Yap, Wei Boon, et al.
Published: (2018)

Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer
by: Ahmad, Umar, et al.
Published: (2023)

The matrix (M) protein of Newcastle disease virus binds to human Bax through its BH3 domain.
by: Molouki, Aidin, et al.
Published: (2011)

Structural analysis of peptides that interact with Newcastle disease virus
by: Chia, Suet Lin, et al.
Published: (2004)

Purification of recombinant nucleocapsid protein of Newcastle disease virus from unclarified feedstock using expanded bed adsorption chromatography
by: Tan, Yan Peng, et al.
Published: (2006)

Comparison of expression for IL-15 and IL-18 on dendritic cells and macrophages upon infection with recombinant fowlpox virus versus wild type fowlpox virus
by: Yusof, Sakinah, et al.
Published: (2015)

IL-17 and TH17 responses to human Helicobacter pylori infection and their association with disease
by: Staples, Emily
Published: (2013)

Investigation of the expression and biological response of the IL-1Rrp2 receptor in human cells
by: Mutamba, Shilla
Published: (2012)

Distal regulatory elements play an important role in regulation of the human IL-5 gene
by: Urwin, Debra, et al.
Published: (2004)

3-Bromo-1-Hydroxy-9,10-Anthraquinone (BHAQ) Inhibits Growth and Migration of the Human Breast Cancer Cell Lines MCF-7 and MDA-MB231
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

Influence of annona muricata linn polymorphism on polyphenolic production and its anti cancer effects
by: Syed Najmuddin, Syed Umar Faruq
Published: (2016)