Analyzing Longitudinal Data Using Gee-Smoothing Spline

This paper considers nonparametric regression to analyze longitudinal data. Some developments of nonparametric regression have been achieved for longitudinal or clustered categorical data. For exponential family distribution, Lin & Carroll [6] considered nonparametric regression for longitudin...

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Main Authors: Ibrahim, Noor Akma, Suliadi
Format: Article
Language:English
English
Published: 2010
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/7923/
http://psasir.upm.edu.my/id/eprint/7923/1/Analyzing%20Longitudinal%20Data%20Using%20Gee.pdf
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author Ibrahim, Noor Akma
Suliadi,
author_facet Ibrahim, Noor Akma
Suliadi,
author_sort Ibrahim, Noor Akma
building UPM Institutional Repository
collection Online Access
description This paper considers nonparametric regression to analyze longitudinal data. Some developments of nonparametric regression have been achieved for longitudinal or clustered categorical data. For exponential family distribution, Lin & Carroll [6] considered nonparametric regression for longitudinal data using GEE-Local Polynomial Kernel (LPK). They showed that in order to obtain an efficient estimator, one must ignore within subject correlation. This means within subject observations should be assumed independent, hence the working correlation matrix must be an identity matrix. With Lin & Carroll [6], to obtain efficient estimates we should ignore correlation that exist in longitudinal data, even if correlation is the interest of the study. In this paper we propose GEE-Smoothing spline to analyze longitudinal data and study the property of the estimator such as the bias, consistency and efficiency. We use natural cubic spline and combine with GEE of Liang & Zeger [5] in estimation. We want to explore numerically, whether the properties of GEE-Smoothing spline are better than of GEE-Local Polynomial Kernel that proposed by Lin & Carrol [6]. Using simulation we show that GEE-Smoothing Spline is better than GEE-local polynomial. The bias of pointwise estimator is decreasing with increasing sample size. The pointwise estimator is also consistent even with incorrect correlation structure, and the most efficient estimate is obtained if the true correlation structure is used.
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spelling upm-79232015-09-28T03:14:56Z http://psasir.upm.edu.my/id/eprint/7923/ Analyzing Longitudinal Data Using Gee-Smoothing Spline Ibrahim, Noor Akma Suliadi, This paper considers nonparametric regression to analyze longitudinal data. Some developments of nonparametric regression have been achieved for longitudinal or clustered categorical data. For exponential family distribution, Lin & Carroll [6] considered nonparametric regression for longitudinal data using GEE-Local Polynomial Kernel (LPK). They showed that in order to obtain an efficient estimator, one must ignore within subject correlation. This means within subject observations should be assumed independent, hence the working correlation matrix must be an identity matrix. With Lin & Carroll [6], to obtain efficient estimates we should ignore correlation that exist in longitudinal data, even if correlation is the interest of the study. In this paper we propose GEE-Smoothing spline to analyze longitudinal data and study the property of the estimator such as the bias, consistency and efficiency. We use natural cubic spline and combine with GEE of Liang & Zeger [5] in estimation. We want to explore numerically, whether the properties of GEE-Smoothing spline are better than of GEE-Local Polynomial Kernel that proposed by Lin & Carrol [6]. Using simulation we show that GEE-Smoothing Spline is better than GEE-local polynomial. The bias of pointwise estimator is decreasing with increasing sample size. The pointwise estimator is also consistent even with incorrect correlation structure, and the most efficient estimate is obtained if the true correlation structure is used. 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/7923/1/Analyzing%20Longitudinal%20Data%20Using%20Gee.pdf Ibrahim, Noor Akma and Suliadi, (2010) Analyzing Longitudinal Data Using Gee-Smoothing Spline. WSEAS Transactions on Systems and Control . ISSN 1790-5117 http://www.wseas.us/e-library/conferences/2009/hangzhou/ACACOS/ACACOS02.pdf Spline theory English
spellingShingle Spline theory
Ibrahim, Noor Akma
Suliadi,
Analyzing Longitudinal Data Using Gee-Smoothing Spline
title Analyzing Longitudinal Data Using Gee-Smoothing Spline
title_full Analyzing Longitudinal Data Using Gee-Smoothing Spline
title_fullStr Analyzing Longitudinal Data Using Gee-Smoothing Spline
title_full_unstemmed Analyzing Longitudinal Data Using Gee-Smoothing Spline
title_short Analyzing Longitudinal Data Using Gee-Smoothing Spline
title_sort analyzing longitudinal data using gee-smoothing spline
topic Spline theory
url http://psasir.upm.edu.my/id/eprint/7923/
http://psasir.upm.edu.my/id/eprint/7923/
http://psasir.upm.edu.my/id/eprint/7923/1/Analyzing%20Longitudinal%20Data%20Using%20Gee.pdf