The myth and therapeutic potentials of postbiotics
Postbiotics (bioactives) are nonviable metabolites produced by probiotics that exert biological effects on the hosts. The myriad beneficial effects of postbiotics produced by six novel bacteriocinogenic Lactobacillus plantarum strains have been proven extensively since 2004, with the broad bacterioc...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Book Section |
| Language: | English |
| Published: |
Academic Press
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/78995/ http://psasir.upm.edu.my/id/eprint/78995/1/The%20myth%20and%20therapeutic%20potentials%20of%20postbiotics.pdf |
| _version_ | 1848858573797326848 |
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| author | Foo, Hooi Ling Loh, Teck Chwen Abdul Mutalib, Nur Elina Abdul Rahim, Raha |
| author2 | Faintuch, Joel |
| author_facet | Faintuch, Joel Foo, Hooi Ling Loh, Teck Chwen Abdul Mutalib, Nur Elina Abdul Rahim, Raha |
| author_sort | Foo, Hooi Ling |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Postbiotics (bioactives) are nonviable metabolites produced by probiotics that exert biological effects on the hosts. The myriad beneficial effects of postbiotics produced by six novel bacteriocinogenic Lactobacillus plantarum strains have been proven extensively since 2004, with the broad bacteriocin inhibitory activity against various pathogens, as they harbor two classes of bacteriocin structural genes (plnEF and pln W). The supplementation of the postbiotics to various animal models has significantly improved serum cholesterol, immune response, overall health, and growth, while suppressing the population of pathogenic bacteria in the digestive tract. Additionally, the postbiotics of these lactobacilli strains demonstrated novel antiproliferation and anticancer activity against various human cancer cell lines by inducing cytotoxicity via apoptotic pathway. |
| first_indexed | 2025-11-15T12:15:36Z |
| format | Book Section |
| id | upm-78995 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:15:36Z |
| publishDate | 2019 |
| publisher | Academic Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-789952021-08-03T10:01:02Z http://psasir.upm.edu.my/id/eprint/78995/ The myth and therapeutic potentials of postbiotics Foo, Hooi Ling Loh, Teck Chwen Abdul Mutalib, Nur Elina Abdul Rahim, Raha Postbiotics (bioactives) are nonviable metabolites produced by probiotics that exert biological effects on the hosts. The myriad beneficial effects of postbiotics produced by six novel bacteriocinogenic Lactobacillus plantarum strains have been proven extensively since 2004, with the broad bacteriocin inhibitory activity against various pathogens, as they harbor two classes of bacteriocin structural genes (plnEF and pln W). The supplementation of the postbiotics to various animal models has significantly improved serum cholesterol, immune response, overall health, and growth, while suppressing the population of pathogenic bacteria in the digestive tract. Additionally, the postbiotics of these lactobacilli strains demonstrated novel antiproliferation and anticancer activity against various human cancer cell lines by inducing cytotoxicity via apoptotic pathway. Academic Press Faintuch, Joel Faintuch, Salomao 2019 Book Section PeerReviewed text en http://psasir.upm.edu.my/id/eprint/78995/1/The%20myth%20and%20therapeutic%20potentials%20of%20postbiotics.pdf Foo, Hooi Ling and Loh, Teck Chwen and Abdul Mutalib, Nur Elina and Abdul Rahim, Raha (2019) The myth and therapeutic potentials of postbiotics. In: Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications. Academic Press, London, 201 - 214. ISBN 9780128152492 https://www.sciencedirect.com/science/article/pii/B978012815249200021X?via%3Dihub#! 10.1016/B978-0-12-815249-2.00021-X |
| spellingShingle | Foo, Hooi Ling Loh, Teck Chwen Abdul Mutalib, Nur Elina Abdul Rahim, Raha The myth and therapeutic potentials of postbiotics |
| title | The myth and therapeutic potentials of postbiotics |
| title_full | The myth and therapeutic potentials of postbiotics |
| title_fullStr | The myth and therapeutic potentials of postbiotics |
| title_full_unstemmed | The myth and therapeutic potentials of postbiotics |
| title_short | The myth and therapeutic potentials of postbiotics |
| title_sort | myth and therapeutic potentials of postbiotics |
| url | http://psasir.upm.edu.my/id/eprint/78995/ http://psasir.upm.edu.my/id/eprint/78995/ http://psasir.upm.edu.my/id/eprint/78995/ http://psasir.upm.edu.my/id/eprint/78995/1/The%20myth%20and%20therapeutic%20potentials%20of%20postbiotics.pdf |