The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle
Selenium (Se) is an essential micronutrient required for normal growth development and antioxidant defense. The objective of this study is to determine the effect of Se supplementation on the oxidative stress (malondialdehyde, MDA and glutathione peroxidase, GSH-Px) and muscle integrity (aspar...
| Main Author: | |
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| Format: | Project Paper Report |
| Language: | English |
| Published: |
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/78177/ http://psasir.upm.edu.my/id/eprint/78177/1/FPV%202016%2018%20-%20IR.pdf |
| _version_ | 1848858435019341824 |
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| author | Hashim, Zharif Atiq |
| author_facet | Hashim, Zharif Atiq |
| author_sort | Hashim, Zharif Atiq |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Selenium (Se) is an essential micronutrient required for normal growth
development and antioxidant defense. The objective of this study is to determine
the effect of Se supplementation on the oxidative stress (malondialdehyde, MDA
and glutathione peroxidase, GSH-Px) and muscle integrity (aspartate transaminase,
AST) in beef cattle. Ten 1-year-old cows were selected randomly and divided into
a control and treatment group. The control group was injected intramuscularly with
10ml normal saline, while the treatment group received two intramuscular
injections of 0.1mg/kg of Se, viz at the start and two weeks post-experimentation. Blood was collected weekly until the fourth week of the experimental period. The
plasma, red blood cell and serum were then subjected to MDA, GSH-Px and AST
assays, respectively. The results showed that there was no significant difference in
the concentration of MDA and AST between both groups. However, the
concentration of GSH-Px showed a significant (p<0.05) increment only on the
weeks 1 and 2 post-treatment. It is concluded that supplementation regime of Se
used may not be effective in abating the oxidative stress and improving muscle integrity in beef cattle. |
| first_indexed | 2025-11-15T12:13:24Z |
| format | Project Paper Report |
| id | upm-78177 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:13:24Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-781772025-01-03T07:25:14Z http://psasir.upm.edu.my/id/eprint/78177/ The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle Hashim, Zharif Atiq Selenium (Se) is an essential micronutrient required for normal growth development and antioxidant defense. The objective of this study is to determine the effect of Se supplementation on the oxidative stress (malondialdehyde, MDA and glutathione peroxidase, GSH-Px) and muscle integrity (aspartate transaminase, AST) in beef cattle. Ten 1-year-old cows were selected randomly and divided into a control and treatment group. The control group was injected intramuscularly with 10ml normal saline, while the treatment group received two intramuscular injections of 0.1mg/kg of Se, viz at the start and two weeks post-experimentation. Blood was collected weekly until the fourth week of the experimental period. The plasma, red blood cell and serum were then subjected to MDA, GSH-Px and AST assays, respectively. The results showed that there was no significant difference in the concentration of MDA and AST between both groups. However, the concentration of GSH-Px showed a significant (p<0.05) increment only on the weeks 1 and 2 post-treatment. It is concluded that supplementation regime of Se used may not be effective in abating the oxidative stress and improving muscle integrity in beef cattle. 2016-03 Project Paper Report NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/78177/1/FPV%202016%2018%20-%20IR.pdf Hashim, Zharif Atiq (2016) The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle. [Project Paper Report] |
| spellingShingle | Hashim, Zharif Atiq The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title | The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title_full | The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title_fullStr | The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title_full_unstemmed | The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title_short | The effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| title_sort | effect of selenium supplement on anti-oxidant status and ast concentration in beef cattle |
| url | http://psasir.upm.edu.my/id/eprint/78177/ http://psasir.upm.edu.my/id/eprint/78177/1/FPV%202016%2018%20-%20IR.pdf |