Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, Caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines

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Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, Caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines

Jatropha meal produced from the kernel of Jatropha curcas Linn. grown in Malaysia contains phorbol esters (PEs). The potential benefits of PEs present in the meal as anticancer agent are still not well understood. Hence, this study was conducted to evaluate the cytotoxic effects and mode of actions...

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Bibliographic Details
Main Authors:	Oskoueian, Ehsan, Abdullah, Norhani, Ahmad, Syahida
Format:	Article
Language:	English
Published:	MDPI 2012
Online Access:	http://psasir.upm.edu.my/id/eprint/78015/ http://psasir.upm.edu.my/id/eprint/78015/1/78015.pdf

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