Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents

This study was conducted to investigate the chemical and nutritional composition of Artemisia annua leaves in addition to determination of antioxidant potential of their extracts prepared in different solvents. Chemical composition was determined by quantifying fat, protein, carbohydrate, fiber, toc...

Full description

Bibliographic Details
Main Authors: Iqbal, Shahid, Younas, Umer, Chan, Kim Wei, Zia-Ul-Haq, Muhammad, Ismail, Maznah
Format: Article
Language:English
Published: MDPI 2012
Online Access:http://psasir.upm.edu.my/id/eprint/78000/
http://psasir.upm.edu.my/id/eprint/78000/1/78000.pdf
_version_ 1848858385293770752
author Iqbal, Shahid
Younas, Umer
Chan, Kim Wei
Zia-Ul-Haq, Muhammad
Ismail, Maznah
author_facet Iqbal, Shahid
Younas, Umer
Chan, Kim Wei
Zia-Ul-Haq, Muhammad
Ismail, Maznah
author_sort Iqbal, Shahid
building UPM Institutional Repository
collection Online Access
description This study was conducted to investigate the chemical and nutritional composition of Artemisia annua leaves in addition to determination of antioxidant potential of their extracts prepared in different solvents. Chemical composition was determined by quantifying fat, protein, carbohydrate, fiber, tocopherol, phytate, and tannin contents. Extraction of A. annua leaves, for antioxidant potential evaluation, was carried out using five solvents of different polarities, i.e., hexane, chloroform, ethyl acetate, methanol and water. Antioxidant potential was evaluated by estimating total phenolic (TPC), flavonoid (TFC) contents, ferric reducing antioxidant power (FRAP), Trolox equivalent antioxidant capacity (TEAC), DPPH radical scavenging activity and lipid peroxidation. Efficiency of different solvents was compared for the yield of antioxidant extracts from leaf samples and a clear variation was observed. The highest TPC, TFC, TEAC, DPPH radical scavenging and lowest lipid peroxidation were observed in MeOH extracts, whereas aqueous extract exhibited high ferric reducing antioxidant power; suggesting MeOH to be the most favorable extractant.
first_indexed 2025-11-15T12:12:36Z
format Article
id upm-78000
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T12:12:36Z
publishDate 2012
publisher MDPI
recordtype eprints
repository_type Digital Repository
spelling upm-780002020-06-01T03:14:18Z http://psasir.upm.edu.my/id/eprint/78000/ Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents Iqbal, Shahid Younas, Umer Chan, Kim Wei Zia-Ul-Haq, Muhammad Ismail, Maznah This study was conducted to investigate the chemical and nutritional composition of Artemisia annua leaves in addition to determination of antioxidant potential of their extracts prepared in different solvents. Chemical composition was determined by quantifying fat, protein, carbohydrate, fiber, tocopherol, phytate, and tannin contents. Extraction of A. annua leaves, for antioxidant potential evaluation, was carried out using five solvents of different polarities, i.e., hexane, chloroform, ethyl acetate, methanol and water. Antioxidant potential was evaluated by estimating total phenolic (TPC), flavonoid (TFC) contents, ferric reducing antioxidant power (FRAP), Trolox equivalent antioxidant capacity (TEAC), DPPH radical scavenging activity and lipid peroxidation. Efficiency of different solvents was compared for the yield of antioxidant extracts from leaf samples and a clear variation was observed. The highest TPC, TFC, TEAC, DPPH radical scavenging and lowest lipid peroxidation were observed in MeOH extracts, whereas aqueous extract exhibited high ferric reducing antioxidant power; suggesting MeOH to be the most favorable extractant. MDPI 2012 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/78000/1/78000.pdf Iqbal, Shahid and Younas, Umer and Chan, Kim Wei and Zia-Ul-Haq, Muhammad and Ismail, Maznah (2012) Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents. Molecules, 17 (5). pp. 6020-6032. ISSN 1420-3049 https://www.mdpi.com/1420-3049/17/5/6020 10.3390/molecules17056020
spellingShingle Iqbal, Shahid
Younas, Umer
Chan, Kim Wei
Zia-Ul-Haq, Muhammad
Ismail, Maznah
Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title_full Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title_fullStr Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title_full_unstemmed Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title_short Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents
title_sort chemical composition of artemisia annua l. leaves and antioxidant potential of extracts as a function of extraction solvents
url http://psasir.upm.edu.my/id/eprint/78000/
http://psasir.upm.edu.my/id/eprint/78000/
http://psasir.upm.edu.my/id/eprint/78000/
http://psasir.upm.edu.my/id/eprint/78000/1/78000.pdf