Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review
Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes catalyzed by transition metals, especially palladium and copper. This is a well known reaction in organic synthesis and plays a role in sp2-sp C-C bond formations. This cross coupling was used in synthesis of natur...
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| Format: | Article |
| Language: | English |
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MDPI
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/77749/ http://psasir.upm.edu.my/id/eprint/77749/1/77749.pdf |
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| author | Kanwal, Iram Mujahid, Aqsa Rasool, Nasir Rizwan, Komal Malik, Ayesha Ahmad, Gulraiz Shah, Syed Adnan Ali Rashid, Umer Mad Nasir, Nadiah |
| author_facet | Kanwal, Iram Mujahid, Aqsa Rasool, Nasir Rizwan, Komal Malik, Ayesha Ahmad, Gulraiz Shah, Syed Adnan Ali Rashid, Umer Mad Nasir, Nadiah |
| author_sort | Kanwal, Iram |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes catalyzed by transition metals, especially palladium and copper. This is a well known reaction in organic synthesis and plays a role in sp2-sp C-C bond formations. This cross coupling was used in synthesis of natural products, biologically active molecules, heterocycles, dendrimers, conjugated polymers and organic complexes. This review paper focuses on developments in the palladium and copper catalyzed Sonogashira cross coupling achieved in recent years concerning substrates, different catalyst systems and reaction conditions. |
| first_indexed | 2025-11-15T12:11:42Z |
| format | Article |
| id | upm-77749 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:11:42Z |
| publishDate | 2020 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-777492020-05-04T16:54:33Z http://psasir.upm.edu.my/id/eprint/77749/ Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review Kanwal, Iram Mujahid, Aqsa Rasool, Nasir Rizwan, Komal Malik, Ayesha Ahmad, Gulraiz Shah, Syed Adnan Ali Rashid, Umer Mad Nasir, Nadiah Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes catalyzed by transition metals, especially palladium and copper. This is a well known reaction in organic synthesis and plays a role in sp2-sp C-C bond formations. This cross coupling was used in synthesis of natural products, biologically active molecules, heterocycles, dendrimers, conjugated polymers and organic complexes. This review paper focuses on developments in the palladium and copper catalyzed Sonogashira cross coupling achieved in recent years concerning substrates, different catalyst systems and reaction conditions. MDPI 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/77749/1/77749.pdf Kanwal, Iram and Mujahid, Aqsa and Rasool, Nasir and Rizwan, Komal and Malik, Ayesha and Ahmad, Gulraiz and Shah, Syed Adnan Ali and Rashid, Umer and Mad Nasir, Nadiah (2020) Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review. Catalysts, 10 (4). art. no. 443. pp. 1-48. ISSN 2073-4344 https://www.mdpi.com/2073-4344/10/4/443 10.3390/catal10040443 |
| spellingShingle | Kanwal, Iram Mujahid, Aqsa Rasool, Nasir Rizwan, Komal Malik, Ayesha Ahmad, Gulraiz Shah, Syed Adnan Ali Rashid, Umer Mad Nasir, Nadiah Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title | Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title_full | Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title_fullStr | Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title_full_unstemmed | Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title_short | Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: a review |
| title_sort | palladium and copper catalyzed sonogashira cross coupling has been an excellent methodology for c-c bond formation for 17 years: a review |
| url | http://psasir.upm.edu.my/id/eprint/77749/ http://psasir.upm.edu.my/id/eprint/77749/ http://psasir.upm.edu.my/id/eprint/77749/ http://psasir.upm.edu.my/id/eprint/77749/1/77749.pdf |