Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus)
A 14-year-old female captive Asian elephant in a Malaysian z oo with a history of positive sero-reactivity to Elephant TB STAT-PAK assay was humanely euthanized due to chronic weight loss and poor response to treatment. Postmortem revealed generalized congestion and emphysematous lungs. Microscopic...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Veterinary Association Malaysia
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/7743/ http://psasir.upm.edu.my/id/eprint/7743/1/7.%20INTERSTITIAL%20PULMONARY%20FIBROSIS%20IN%20A%20MALAYSIAN%20CAPTIVE%20ASIAN%20ELEPHANT.pdf |
| _version_ | 1848840680533655552 |
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| author | Yakubu, Yusuf Ong, Bee Lee Mohamed Mustapha, Noordin Zakaria, Zunita Jayaseelan, K. Kumar Sharma, Reuben Sunil Sugnaseelan, Sumita Firdaus, M. Kamarudin, Zubaidah Ngeow, Yun Fong |
| author_facet | Yakubu, Yusuf Ong, Bee Lee Mohamed Mustapha, Noordin Zakaria, Zunita Jayaseelan, K. Kumar Sharma, Reuben Sunil Sugnaseelan, Sumita Firdaus, M. Kamarudin, Zubaidah Ngeow, Yun Fong |
| author_sort | Yakubu, Yusuf |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A 14-year-old female captive Asian elephant in a Malaysian z
oo with a history of positive sero-reactivity to Elephant TB STAT-PAK assay was humanely euthanized due to chronic weight loss and poor response to treatment. Postmortem revealed generalized congestion and emphysematous lungs. Microscopically, there were severe pulmonary emphysema, eosinophilic hyaline membrane and infiltration of mature fibrocytes in the alveolar walls. Based on the histopathological findings interstitial pulmonary
fibrosis was diagnosed. The possible cause of which although not completely known, is most likely due to hypersensitivity. The allergic reaction could have been caused by exposure to antigens of avian origin or the
Mycobacterium gilvum, an non-tuberculous
mycobacterium (NTM), isolated from the lung. This is the second case reported in elephants globally, thought it has been well studied in humans and reported in horses. Providing good husbandry for elephants in captivity is important to reduce the occurrence of such condition. |
| first_indexed | 2025-11-15T07:31:12Z |
| format | Article |
| id | upm-7743 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:31:12Z |
| publishDate | 2014 |
| publisher | Veterinary Association Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-77432016-11-21T07:27:27Z http://psasir.upm.edu.my/id/eprint/7743/ Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) Yakubu, Yusuf Ong, Bee Lee Mohamed Mustapha, Noordin Zakaria, Zunita Jayaseelan, K. Kumar Sharma, Reuben Sunil Sugnaseelan, Sumita Firdaus, M. Kamarudin, Zubaidah Ngeow, Yun Fong A 14-year-old female captive Asian elephant in a Malaysian z oo with a history of positive sero-reactivity to Elephant TB STAT-PAK assay was humanely euthanized due to chronic weight loss and poor response to treatment. Postmortem revealed generalized congestion and emphysematous lungs. Microscopically, there were severe pulmonary emphysema, eosinophilic hyaline membrane and infiltration of mature fibrocytes in the alveolar walls. Based on the histopathological findings interstitial pulmonary fibrosis was diagnosed. The possible cause of which although not completely known, is most likely due to hypersensitivity. The allergic reaction could have been caused by exposure to antigens of avian origin or the Mycobacterium gilvum, an non-tuberculous mycobacterium (NTM), isolated from the lung. This is the second case reported in elephants globally, thought it has been well studied in humans and reported in horses. Providing good husbandry for elephants in captivity is important to reduce the occurrence of such condition. Veterinary Association Malaysia 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/7743/1/7.%20INTERSTITIAL%20PULMONARY%20FIBROSIS%20IN%20A%20MALAYSIAN%20CAPTIVE%20ASIAN%20ELEPHANT.pdf Yakubu, Yusuf and Ong, Bee Lee and Mohamed Mustapha, Noordin and Zakaria, Zunita and Jayaseelan, K. and Kumar Sharma, Reuben Sunil and Sugnaseelan, Sumita and Firdaus, M. and Kamarudin, Zubaidah and Ngeow, Yun Fong (2014) Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus). Jurnal Veterinar Malaysia, 26 (1&2). pp. 34-37. ISSN 9128-2506 |
| spellingShingle | Yakubu, Yusuf Ong, Bee Lee Mohamed Mustapha, Noordin Zakaria, Zunita Jayaseelan, K. Kumar Sharma, Reuben Sunil Sugnaseelan, Sumita Firdaus, M. Kamarudin, Zubaidah Ngeow, Yun Fong Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title | Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title_full | Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title_fullStr | Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title_full_unstemmed | Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title_short | Interstitial pulmonary fibrosis in a Malaysian captive Asian elephant (Elephas maximus) |
| title_sort | interstitial pulmonary fibrosis in a malaysian captive asian elephant (elephas maximus) |
| url | http://psasir.upm.edu.my/id/eprint/7743/ http://psasir.upm.edu.my/id/eprint/7743/1/7.%20INTERSTITIAL%20PULMONARY%20FIBROSIS%20IN%20A%20MALAYSIAN%20CAPTIVE%20ASIAN%20ELEPHANT.pdf |