Diagnostic methods for feline coronavirus: a review
Feline coronaviruses (FCoVs) are found throughout the world. Infection with FCoV can result in a diverse range of signs from clinically inapparent infections to a highly fatal disease called feline infectious peritonitis (FIP). FIP is one of the most serious viral diseases of cats. While there is ne...
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| Format: | Article |
| Language: | English |
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SAGE-Hindawi Access to Research
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/7722/ http://psasir.upm.edu.my/id/eprint/7722/1/809480.pdf |
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| author | Sharif, Saeed Arshad, Siti Suri Bejo, Mohd Hair Omar, Abdul Rahman Allaudin, Zeenathul Nazariah Alazawy, Amer |
| author_facet | Sharif, Saeed Arshad, Siti Suri Bejo, Mohd Hair Omar, Abdul Rahman Allaudin, Zeenathul Nazariah Alazawy, Amer |
| author_sort | Sharif, Saeed |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Feline coronaviruses (FCoVs) are found throughout the world. Infection with FCoV can result in a diverse range of signs from clinically inapparent infections to a highly fatal disease called feline infectious peritonitis (FIP). FIP is one of the most serious viral diseases of cats. While there is neither an effective vaccine, nor a curative treatment for FIP, a diagnostic protocol for FCoV would greatly assist in the management and control of the virus. Clinical findings in FIP are non-specific and not helpful in making a differential diagnosis. Haematological and biochemical abnormalities in FIP cases are also non-specific. The currently available serological tests have low specificity and sensitivity for detection of active infection and cross-react with FCoV strains of low pathogenicity, the feline enteric coronaviruses (FECV). Reverse transcriptase polymerase chain reaction (RT-PCR) has been used to detect FCoV and is rapid and sensitive, but results must be interpreted in the context of clinical findings. At present, a definitive diagnosis of FIP can be established only by histopathological examination of biopsies. This paper describes and compares diagnostic methods for FCoVs and includes a brief account of the virus biology, epidemiology, and pathogenesis. |
| first_indexed | 2025-11-15T07:31:06Z |
| format | Article |
| id | upm-7722 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:31:06Z |
| publishDate | 2010 |
| publisher | SAGE-Hindawi Access to Research |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-77222019-10-30T03:21:18Z http://psasir.upm.edu.my/id/eprint/7722/ Diagnostic methods for feline coronavirus: a review Sharif, Saeed Arshad, Siti Suri Bejo, Mohd Hair Omar, Abdul Rahman Allaudin, Zeenathul Nazariah Alazawy, Amer Feline coronaviruses (FCoVs) are found throughout the world. Infection with FCoV can result in a diverse range of signs from clinically inapparent infections to a highly fatal disease called feline infectious peritonitis (FIP). FIP is one of the most serious viral diseases of cats. While there is neither an effective vaccine, nor a curative treatment for FIP, a diagnostic protocol for FCoV would greatly assist in the management and control of the virus. Clinical findings in FIP are non-specific and not helpful in making a differential diagnosis. Haematological and biochemical abnormalities in FIP cases are also non-specific. The currently available serological tests have low specificity and sensitivity for detection of active infection and cross-react with FCoV strains of low pathogenicity, the feline enteric coronaviruses (FECV). Reverse transcriptase polymerase chain reaction (RT-PCR) has been used to detect FCoV and is rapid and sensitive, but results must be interpreted in the context of clinical findings. At present, a definitive diagnosis of FIP can be established only by histopathological examination of biopsies. This paper describes and compares diagnostic methods for FCoVs and includes a brief account of the virus biology, epidemiology, and pathogenesis. SAGE-Hindawi Access to Research 2010 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/7722/1/809480.pdf Sharif, Saeed and Arshad, Siti Suri and Bejo, Mohd Hair and Omar, Abdul Rahman and Allaudin, Zeenathul Nazariah and Alazawy, Amer (2010) Diagnostic methods for feline coronavirus: a review. Veterinary Medicine International, 2010. art. no. 809480. pp. 1-7. ISSN 2090-8113; ESSN: 2042-0048 https://www.hindawi.com/journals/vmi/2010/809480/abs/ 10.4061/2010/809480 |
| spellingShingle | Sharif, Saeed Arshad, Siti Suri Bejo, Mohd Hair Omar, Abdul Rahman Allaudin, Zeenathul Nazariah Alazawy, Amer Diagnostic methods for feline coronavirus: a review |
| title | Diagnostic methods for feline coronavirus: a review |
| title_full | Diagnostic methods for feline coronavirus: a review |
| title_fullStr | Diagnostic methods for feline coronavirus: a review |
| title_full_unstemmed | Diagnostic methods for feline coronavirus: a review |
| title_short | Diagnostic methods for feline coronavirus: a review |
| title_sort | diagnostic methods for feline coronavirus: a review |
| url | http://psasir.upm.edu.my/id/eprint/7722/ http://psasir.upm.edu.my/id/eprint/7722/ http://psasir.upm.edu.my/id/eprint/7722/ http://psasir.upm.edu.my/id/eprint/7722/1/809480.pdf |