Hyalinizing clear cell carcinoma of the soft palate - a case report

Hyalinizing clear cell carcinoma presents as a painless submucosal mass commonly located at the palate and base of tongue. It is a rare tumour and has often been misdiagnosed for other more common tumours with clear cytoplasm, such as acinic cell carcinoma, clear cell oncocytoma or mucoepidermoid ca...

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Main Authors: Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin, Subha, Sethu Thakachy, Doi, Mohamad, Adzman, Sellymiah
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2020
Online Access:http://psasir.upm.edu.my/id/eprint/76942/
http://psasir.upm.edu.my/id/eprint/76942/1/2020011612300549_MJMHS_0093.pdf
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author Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin
Subha, Sethu Thakachy
Doi, Mohamad
Adzman, Sellymiah
author_facet Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin
Subha, Sethu Thakachy
Doi, Mohamad
Adzman, Sellymiah
author_sort Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin
building UPM Institutional Repository
collection Online Access
description Hyalinizing clear cell carcinoma presents as a painless submucosal mass commonly located at the palate and base of tongue. It is a rare tumour and has often been misdiagnosed for other more common tumours with clear cytoplasm, such as acinic cell carcinoma, clear cell oncocytoma or mucoepidermoid carcinoma. HCCC has been reported as a low grade malignant tumour with a high rate of cervical metastases. Due to its rarity, there is no treatment protocol. However, the treatment of choice is wide local excision and the neck disease is treated with neck dissection or radiotherapy or both with no conclusive outcome as incidence is too low or underreported with no long term follow up. Our case highlights the diagnosis difficulties in such rare cases, and the need for longer follow up post excision to determine outcome and recurrence rates.
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spelling upm-769422020-03-03T09:20:03Z http://psasir.upm.edu.my/id/eprint/76942/ Hyalinizing clear cell carcinoma of the soft palate - a case report Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin Subha, Sethu Thakachy Doi, Mohamad Adzman, Sellymiah Hyalinizing clear cell carcinoma presents as a painless submucosal mass commonly located at the palate and base of tongue. It is a rare tumour and has often been misdiagnosed for other more common tumours with clear cytoplasm, such as acinic cell carcinoma, clear cell oncocytoma or mucoepidermoid carcinoma. HCCC has been reported as a low grade malignant tumour with a high rate of cervical metastases. Due to its rarity, there is no treatment protocol. However, the treatment of choice is wide local excision and the neck disease is treated with neck dissection or radiotherapy or both with no conclusive outcome as incidence is too low or underreported with no long term follow up. Our case highlights the diagnosis difficulties in such rare cases, and the need for longer follow up post excision to determine outcome and recurrence rates. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/76942/1/2020011612300549_MJMHS_0093.pdf Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin and Subha, Sethu Thakachy and Doi, Mohamad and Adzman, Sellymiah (2020) Hyalinizing clear cell carcinoma of the soft palate - a case report. Malaysian Journal of Medicine and Health Sciences, 16 (1). pp. 333-335. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2020011612300549_MJMHS_0093.pdf
spellingShingle Syed Ahmad Fauzi, Sharifah Intan Safuraa Shahabudin
Subha, Sethu Thakachy
Doi, Mohamad
Adzman, Sellymiah
Hyalinizing clear cell carcinoma of the soft palate - a case report
title Hyalinizing clear cell carcinoma of the soft palate - a case report
title_full Hyalinizing clear cell carcinoma of the soft palate - a case report
title_fullStr Hyalinizing clear cell carcinoma of the soft palate - a case report
title_full_unstemmed Hyalinizing clear cell carcinoma of the soft palate - a case report
title_short Hyalinizing clear cell carcinoma of the soft palate - a case report
title_sort hyalinizing clear cell carcinoma of the soft palate - a case report
url http://psasir.upm.edu.my/id/eprint/76942/
http://psasir.upm.edu.my/id/eprint/76942/
http://psasir.upm.edu.my/id/eprint/76942/1/2020011612300549_MJMHS_0093.pdf