A new cytotoxic carbazole alkaloid from Clausena excavata
A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds we...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2007
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/7660/ http://psasir.upm.edu.my/id/eprint/7660/1/A%20new%20Cytotoxic%20Carbazole%20Alkaloid%20from%20Clausena%20excavata.pdf |
| _version_ | 1848840657772216320 |
|---|---|
| author | Yap, Taufiq Yun Hin Peh, Tian Hai Ee, Gwendoline Cheng Lian Rahmani, Mawardi Md. Sukari, Mohd Aspollah Ali, Abdul Manaf Muse, Radzali |
| author_facet | Yap, Taufiq Yun Hin Peh, Tian Hai Ee, Gwendoline Cheng Lian Rahmani, Mawardi Md. Sukari, Mohd Aspollah Ali, Abdul Manaf Muse, Radzali |
| author_sort | Yap, Taufiq Yun Hin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line. |
| first_indexed | 2025-11-15T07:30:50Z |
| format | Article |
| id | upm-7660 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:30:50Z |
| publishDate | 2007 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-76602016-11-24T08:42:12Z http://psasir.upm.edu.my/id/eprint/7660/ A new cytotoxic carbazole alkaloid from Clausena excavata Yap, Taufiq Yun Hin Peh, Tian Hai Ee, Gwendoline Cheng Lian Rahmani, Mawardi Md. Sukari, Mohd Aspollah Ali, Abdul Manaf Muse, Radzali A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line. Taylor & Francis 2007 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/7660/1/A%20new%20Cytotoxic%20Carbazole%20Alkaloid%20from%20Clausena%20excavata.pdf Yap, Taufiq Yun Hin and Peh, Tian Hai and Ee, Gwendoline Cheng Lian and Rahmani, Mawardi and Md. Sukari, Mohd Aspollah and Ali, Abdul Manaf and Muse, Radzali (2007) A new cytotoxic carbazole alkaloid from Clausena excavata. Natural Product Research, 21 (9). pp. 810-813. ISSN 1478-6419; ESSN: 1478-6427 http://dx.doi.org/10.1080/14786410701258875 10.1080/14786410701258875 |
| spellingShingle | Yap, Taufiq Yun Hin Peh, Tian Hai Ee, Gwendoline Cheng Lian Rahmani, Mawardi Md. Sukari, Mohd Aspollah Ali, Abdul Manaf Muse, Radzali A new cytotoxic carbazole alkaloid from Clausena excavata |
| title | A new cytotoxic carbazole alkaloid from Clausena excavata |
| title_full | A new cytotoxic carbazole alkaloid from Clausena excavata |
| title_fullStr | A new cytotoxic carbazole alkaloid from Clausena excavata |
| title_full_unstemmed | A new cytotoxic carbazole alkaloid from Clausena excavata |
| title_short | A new cytotoxic carbazole alkaloid from Clausena excavata |
| title_sort | new cytotoxic carbazole alkaloid from clausena excavata |
| url | http://psasir.upm.edu.my/id/eprint/7660/ http://psasir.upm.edu.my/id/eprint/7660/ http://psasir.upm.edu.my/id/eprint/7660/ http://psasir.upm.edu.my/id/eprint/7660/1/A%20new%20Cytotoxic%20Carbazole%20Alkaloid%20from%20Clausena%20excavata.pdf |