Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most comm...
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| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/76448/ http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf |
| _version_ | 1848857970769657856 |
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| author | Al-Battawi, Samer Ho, Yu Bin Latif, Mohd Talib How, Vivien Karuppiah, Thilakavathy |
| author_facet | Al-Battawi, Samer Ho, Yu Bin Latif, Mohd Talib How, Vivien Karuppiah, Thilakavathy |
| author_sort | Al-Battawi, Samer |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatography is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GC-MS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples. |
| first_indexed | 2025-11-15T12:06:01Z |
| format | Article |
| id | upm-76448 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T12:06:01Z |
| publishDate | 2019 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-764482020-02-04T04:53:59Z http://psasir.upm.edu.my/id/eprint/76448/ Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review Al-Battawi, Samer Ho, Yu Bin Latif, Mohd Talib How, Vivien Karuppiah, Thilakavathy Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatography is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GC-MS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf Al-Battawi, Samer and Ho, Yu Bin and Latif, Mohd Talib and How, Vivien and Karuppiah, Thilakavathy (2019) Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review. Malaysian Journal of Medicine and Health Sciences, 15 (SP4). pp. 165-169. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019121207430924_MJMHS_0326.pdf |
| spellingShingle | Al-Battawi, Samer Ho, Yu Bin Latif, Mohd Talib How, Vivien Karuppiah, Thilakavathy Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title | Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title_full | Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title_fullStr | Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title_full_unstemmed | Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title_short | Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| title_sort | determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review |
| url | http://psasir.upm.edu.my/id/eprint/76448/ http://psasir.upm.edu.my/id/eprint/76448/ http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf |