Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia

Introduction: Accumulation of heavy metals through seafood consumption constitutes a significant potential threat to human health. Biomonitoring of whole blood heavy metals level gave an insight into the internal body burden to the exposure of heavy metals. The aims of this study were to assess the...

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Main Authors: Mohd Noor, Farrah Atiqah, Mohd Elias, Saliza, Aris, Ahmad Zaharin, Abu Bakar @ Jamaludin, Suhaili, Md Zulkifli, Hamizah
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/76430/
http://psasir.upm.edu.my/id/eprint/76430/1/2019121207301503_MJMHS_0302.pdf
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author Mohd Noor, Farrah Atiqah
Mohd Elias, Saliza
Aris, Ahmad Zaharin
Abu Bakar @ Jamaludin, Suhaili
Md Zulkifli, Hamizah
author_facet Mohd Noor, Farrah Atiqah
Mohd Elias, Saliza
Aris, Ahmad Zaharin
Abu Bakar @ Jamaludin, Suhaili
Md Zulkifli, Hamizah
author_sort Mohd Noor, Farrah Atiqah
building UPM Institutional Repository
collection Online Access
description Introduction: Accumulation of heavy metals through seafood consumption constitutes a significant potential threat to human health. Biomonitoring of whole blood heavy metals level gave an insight into the internal body burden to the exposure of heavy metals. The aims of this study were to assess the blood heavy metals (arsenic and lead) level among the coastal community of Melaka and to determine their association with sociodemographic background and potential sources of heavy metals accumulation. Methods: Respondents were recruited through purposive sampling technique based on inclusion and exclusion criteria. The questionnaires were distributed to obtain sociodemographic information, the frequency of seafood intake and smoking habit. Blood samples were obtained on a voluntary basis. A total of 63 respondents completed all the information required. The heavy metals concentration in blood was determined by inductively coupled plasma- mass spectrometry (ICP-MS). Results: The blood arsenic (BAs) concentration of respondents was 0.076 (0.059 – 0.107) μg/L and the blood lead (BPb) concentration of respondents was 1.204 (0.670 – 2.094) μg/L respectively. A significant association was observed between seafood-based product frequency intake and BPb concentration (p < 0.05). Other seafood frequency intake and background factors were not significantly associated with the BAs and BPb concentration of respondents. Conclusion: The findings showed that arsenic and lead levels in the blood of respondents along the coastal area of Melaka did not exceed the blood heavy metals reference levels and there was also lack of associations between blood heavy metals concentration and the potential factors of heavy metals accumulation studied.
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spelling upm-764302020-02-04T04:52:23Z http://psasir.upm.edu.my/id/eprint/76430/ Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia Mohd Noor, Farrah Atiqah Mohd Elias, Saliza Aris, Ahmad Zaharin Abu Bakar @ Jamaludin, Suhaili Md Zulkifli, Hamizah Introduction: Accumulation of heavy metals through seafood consumption constitutes a significant potential threat to human health. Biomonitoring of whole blood heavy metals level gave an insight into the internal body burden to the exposure of heavy metals. The aims of this study were to assess the blood heavy metals (arsenic and lead) level among the coastal community of Melaka and to determine their association with sociodemographic background and potential sources of heavy metals accumulation. Methods: Respondents were recruited through purposive sampling technique based on inclusion and exclusion criteria. The questionnaires were distributed to obtain sociodemographic information, the frequency of seafood intake and smoking habit. Blood samples were obtained on a voluntary basis. A total of 63 respondents completed all the information required. The heavy metals concentration in blood was determined by inductively coupled plasma- mass spectrometry (ICP-MS). Results: The blood arsenic (BAs) concentration of respondents was 0.076 (0.059 – 0.107) μg/L and the blood lead (BPb) concentration of respondents was 1.204 (0.670 – 2.094) μg/L respectively. A significant association was observed between seafood-based product frequency intake and BPb concentration (p < 0.05). Other seafood frequency intake and background factors were not significantly associated with the BAs and BPb concentration of respondents. Conclusion: The findings showed that arsenic and lead levels in the blood of respondents along the coastal area of Melaka did not exceed the blood heavy metals reference levels and there was also lack of associations between blood heavy metals concentration and the potential factors of heavy metals accumulation studied. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/76430/1/2019121207301503_MJMHS_0302.pdf Mohd Noor, Farrah Atiqah and Mohd Elias, Saliza and Aris, Ahmad Zaharin and Abu Bakar @ Jamaludin, Suhaili and Md Zulkifli, Hamizah (2019) Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia. Malaysian Journal of Medicine and Health Sciences, 15 (SP4). pp. 19-25. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019121207301503_MJMHS_0302.pdf
spellingShingle Mohd Noor, Farrah Atiqah
Mohd Elias, Saliza
Aris, Ahmad Zaharin
Abu Bakar @ Jamaludin, Suhaili
Md Zulkifli, Hamizah
Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title_full Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title_fullStr Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title_full_unstemmed Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title_short Determination of arsenic and lead level in blood of adults from coastal community in Melaka, Malaysia
title_sort determination of arsenic and lead level in blood of adults from coastal community in melaka, malaysia
url http://psasir.upm.edu.my/id/eprint/76430/
http://psasir.upm.edu.my/id/eprint/76430/
http://psasir.upm.edu.my/id/eprint/76430/1/2019121207301503_MJMHS_0302.pdf