Concurrent inheritance of deletional a-thalassaemia in Malays with HbE trait
Introduction: HbE is the commonest beta haemoglobin (Hb) variant in Southeast Asia. It causes a reduction in synthesis of the beta-globin E chain. Studies indicate HbE coinherited with a-thalassaemia leads to milder clinical phenotype. This study investigates the commitant inheritance of a-thalass...
| Main Authors: | Teh, Lai Kuan, George, Elizabeth, Lai, Mei I., Ahmad, Rahimah, Zakaria, Zubaidah, Tan, Mary Anne Jin Ai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2009
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/7629/ http://psasir.upm.edu.my/id/eprint/7629/1/Concurrent%20inheritance%20of%20deletional%20a-thalassaemia%20in%20Malays%20with%20HbE%20trait.pdf |
Similar Items
HbE β-Thalassaemia in Malaysia: revisited
by: George, Elizabeth
Published: (2013)
by: George, Elizabeth
Published: (2013)
HbA2 levels in β-thalassaemia carriers with the Filipino β0-deletion: are the levels higher than what is found with non-deletional forms of β0-thalassaemia?
by: George, Elizabeth, et al.
Published: (2013)
by: George, Elizabeth, et al.
Published: (2013)
Effects of transfusion and splenectomy on globin chain expression in NTDT HbE/β-thalassaemia
by: Lim, Wai Feng, et al.
Published: (2021)
by: Lim, Wai Feng, et al.
Published: (2021)
The HbA2 levels in normal, B-thalassaemia and haemoglobin E heterozygotes and haemoglobin E (HbE) level in HbE heterozygotes by capillary electrophoresis system
by: Hafiza A,, et al.
Published: (2011)
by: Hafiza A,, et al.
Published: (2011)
Putative role of Bach1 gene in HbE/beta-thalassaemia patients
by: Lee, Tze Yan
Published: (2013)
by: Lee, Tze Yan
Published: (2013)
Association of Alpha Haemoglobin Stabilizing Protein in HbE/ Beta-Thalassaemia Patients in Malaysia
by: Lim, Wai Feng
Published: (2011)
by: Lim, Wai Feng
Published: (2011)
Haplotype analysis of β-Thalassaemia major and carriers with Filipino β°-deletion in Sabah, Malaysia
by: Teh, Lai Kuan, et al.
Published: (2018)
by: Teh, Lai Kuan, et al.
Published: (2018)
Interaction of Hb South Florida (codon 1; GTG→ATG) and HbE, with β-thalassemia (IVS1-1; G→A): expression of different clinical phenotypes
by: Tan, Mary Anne Jin Ai, et al.
Published: (2009)
by: Tan, Mary Anne Jin Ai, et al.
Published: (2009)
Non-deletional alpha thalassaemia: a review of emerging therapy
by: Khairil Wahidin, Nurfhaezah, et al.
Published: (2021)
by: Khairil Wahidin, Nurfhaezah, et al.
Published: (2021)
Haematological parameter evaluation in different types of deletional alpha thalassaemia and in coinheritance of deletional alpha thalassaemia and beta thalassaemia in Hospital Universiti Sains Malaysia
by: Arifin, Samilawati Mohd
Published: (2018)
by: Arifin, Samilawati Mohd
Published: (2018)
A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC)
by: George, Elizabeth, et al.
Published: (2009)
by: George, Elizabeth, et al.
Published: (2009)
Erythrocyte zinc protoporphyrin in beta-thalassaemia carriers
by: George, Elizabeth, et al.
Published: (2008)
by: George, Elizabeth, et al.
Published: (2008)
Rapid detection of α-thalassaemia variants using droplet digital PCR
by: Lee, Tze Yan, et al.
Published: (2016)
by: Lee, Tze Yan, et al.
Published: (2016)
HbE dan diabetis melitus lapuran akhir projek jangka
by: Mazlan, Musalmah, et al.
Published: (2003)
by: Mazlan, Musalmah, et al.
Published: (2003)
Screening for intermediate and severe forms of thalassaemia in discarded red blood cells: optimization and feasibility
by: George, Elizabeth, et al.
Published: (2011)
by: George, Elizabeth, et al.
Published: (2011)
Co-inheritance of Southeast Asian ovalocytosis and Hb E: does it affect the red blood cells indices?
by: Riahi, Shahrzard, et al.
Published: (2017)
by: Riahi, Shahrzard, et al.
Published: (2017)
Differential gene expression
Analyses in HBE/BETA thalassaemia
patients and their relationship to
disease severity
by: Alsaleh, Heba A. A.
Published: (2022)
by: Alsaleh, Heba A. A.
Published: (2022)
Haematology, genetics and molecular epidemiology of deletional alpha thalassaemia in Malaysia
by: Mohd Yacob, Aliza
Published: (2011)
by: Mohd Yacob, Aliza
Published: (2011)
Public perceptions and attitudes toward thalassaemia: influencing factors in a multi-racial population
by: Wong, Li Ping, et al.
Published: (2011)
by: Wong, Li Ping, et al.
Published: (2011)
Molecular characterisation of beta thalassaemia in patients from Sabah, Malaysia
by: Teh, Lai Kuan
Published: (2014)
by: Teh, Lai Kuan
Published: (2014)
Hb lepore/β0-thalassaemia with α+-thalassaemia interactions, a potential diagnostic pitfall
by: Hafiza, Alauddin, et al.
Published: (2015)
by: Hafiza, Alauddin, et al.
Published: (2015)
The use of Taqman genotyping assays for rapid confirmation of B-thalassaemia mutations in the Malays: accurate diagnosis with low DNA concentrations
by: Teh, L. K., et al.
Published: (2015)
by: Teh, L. K., et al.
Published: (2015)
Expression Level of Pro-Apoptotic Genes Determine
Disease Severity of HbE/Beta thalassemia
by: Hassan, Rosline
Published: (2019)
by: Hassan, Rosline
Published: (2019)
Beta-thalassaemia major – a public health problem in Malaysia: impacts, coping strategies and needs of parents with affected children
by: Muhammad, Nursalihah, et al.
Published: (2012)
by: Muhammad, Nursalihah, et al.
Published: (2012)
Detection on common deletional alpha thalassaemia in pregnant women by polymerase chain reaction techniques
by: Fathma Abdullah, Nurul Ain
Published: (2015)
by: Fathma Abdullah, Nurul Ain
Published: (2015)
Development of reverse dot blot hybridisation strip assays to identify common beta-thalassaemia alleles in Malays and Chinese in Malaysia
by: Teh, Lai Kuan
Published: (2010)
by: Teh, Lai Kuan
Published: (2010)
Screening of thalassaemia carriers and its limitations
by: George, Elizabeth
Published: (2014)
by: George, Elizabeth
Published: (2014)
Determination of alpha hemoglobin stabilizing protein (AHSP) gene expression and oxidative stress parameters in HbE/beta-Thalassemia
by: Yaacob, Nur Suraya Che
Published: (2021)
by: Yaacob, Nur Suraya Che
Published: (2021)
Comparison of macular thickness, retinal nerve fiber layer thickness and optic nerve head parameters in HbE/Beta thalassemia and control
by: Dezhao, Sai
Published: (2016)
by: Dezhao, Sai
Published: (2016)
An assessment of three noncommercial DNA extraction methods from dried blood spots for beta-thalassaemia mutation identification.
by: Kartipan, S. N., et al.
Published: (2011)
by: Kartipan, S. N., et al.
Published: (2011)
Thalassemia intermedia in HbH-CS disease with compound heterozygosity for β-thalassemia: challenges in hemoglobin analysis and clinical diagnosis
by: Tan, Mary Anne Jin Ai, et al.
Published: (2009)
by: Tan, Mary Anne Jin Ai, et al.
Published: (2009)
HB MELAYU™ an instrument to measure social character traits.
by: Universiti Putra Malaysia, Research Management Centre
Published: (2011)
by: Universiti Putra Malaysia, Research Management Centre
Published: (2011)
Alpha thalassaemia due to non-deletional mutations on the -3.7 alpha globin fusion gene: Laboratory diagnosis and clinical importance
by: Chow, A., et al.
Published: (2013)
by: Chow, A., et al.
Published: (2013)
Usefulness of red blood cell size factor (RSf) in screening genetic variants of alpha thalassaemia thalassaemia trait regardless of iron status
by: Idris, Nur Juliana, et al.
Published: (2018)
by: Idris, Nur Juliana, et al.
Published: (2018)
Molecular basis of transfusion dependent beta-thalassemia major patients in Sabah
by: Teh, Lai Kuan, et al.
Published: (2014)
by: Teh, Lai Kuan, et al.
Published: (2014)
Identification of α°-thalassaemia (–SEA) using an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chain detection – a preliminary study
by: Tan, Mary Anne Jin Ai, et al.
Published: (2006)
by: Tan, Mary Anne Jin Ai, et al.
Published: (2006)
Screening for thalassaemia in pregnant women: a laboratory perspective
by: George, Elizabeth, et al.
Published: (2005)
by: George, Elizabeth, et al.
Published: (2005)
Coinheritance of haemoglobin e trait with alpha thalassaemia among Malay students in national thalassaemia screening programme in Hospital Sultanah Nur Zahirah Kuala Terengganu
by: Somasundram, Suguna, et al.
Published: (2021)
by: Somasundram, Suguna, et al.
Published: (2021)
Haematologic profile of haemoglobin constant spring and its co-inheritance with alpha and beta thalassaemia among form four students in Negeri Sembilan
by: Nahanthiran, Subithira, et al.
Published: (2022)
by: Nahanthiran, Subithira, et al.
Published: (2022)
Screening of Alpha-Thalassaemia 1 in Beta-Thalassaemia Carriers
by: Chong, Yi Min
Published: (2005)
by: Chong, Yi Min
Published: (2005)
Similar Items
-
HbE β-Thalassaemia in Malaysia: revisited
by: George, Elizabeth
Published: (2013) -
HbA2 levels in β-thalassaemia carriers with the Filipino β0-deletion: are the levels higher than what is found with non-deletional forms of β0-thalassaemia?
by: George, Elizabeth, et al.
Published: (2013) -
Effects of transfusion and splenectomy on globin chain expression in NTDT HbE/β-thalassaemia
by: Lim, Wai Feng, et al.
Published: (2021) -
The HbA2 levels in normal, B-thalassaemia and haemoglobin E heterozygotes and haemoglobin E (HbE) level in HbE heterozygotes by capillary electrophoresis system
by: Hafiza A,, et al.
Published: (2011) -
Putative role of Bach1 gene in HbE/beta-thalassaemia patients
by: Lee, Tze Yan
Published: (2013)