Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and Iκ-B phosphorylation in RAW 264.7 macrophage cells

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Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and Iκ-B phosphorylation in RAW 264.7 macrophage cells

Cardamonin, a chalcone isolated from the fruits of a local plant Alpinia rafflesiana, has demonstrated anti-inflammatory activity in cellular models of inflammation. In this report, we evaluated the ability of cardamonin to suppress both NO and PGE2 synthesis, iNOS and COX-2 expression and enzymatic...

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Bibliographic Details
Main Authors:	Israf Ali, Daud Ahmad, Tajul Arifin, Khaizurin, Ahmad, Syahida, Lajis, Md Nordin, Shari, Khozirah
Format:	Article
Language:	English English
Published:	Elsevier 2007
Online Access:	http://psasir.upm.edu.my/id/eprint/7521/ http://psasir.upm.edu.my/id/eprint/7521/1/Cardamonin%20inhibits%20COX%20and%20iNOS%20expression%20via%20inhibition%20of%20p65NF.pdf

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