Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study
In an attempt to profile the metabolites of three different varieties of germinated rice, specifically black (GBR), red, and white rice, a 1H-nuclear-magnetic-resonance-based metabolomics approach was conducted. Multivariate data analysis was applied to discriminate between the three different varie...
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| Format: | Article |
| Language: | English |
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National Laboratories of Foods and Drugs
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/74943/ http://psasir.upm.edu.my/id/eprint/74943/1/Metabolite.pdf |
| _version_ | 1848857577998254080 |
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| author | Pramai, Phaiwan Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, Maulidiani Abas, Faridah Jiamyangyuen, Sudarat |
| author_facet | Pramai, Phaiwan Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, Maulidiani Abas, Faridah Jiamyangyuen, Sudarat |
| author_sort | Pramai, Phaiwan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In an attempt to profile the metabolites of three different varieties of germinated rice, specifically black (GBR), red, and white rice, a 1H-nuclear-magnetic-resonance-based metabolomics approach was conducted. Multivariate data analysis was applied to discriminate between the three different varieties using a partial least squares discriminant analysis (PLS-DA) model. The PLS model was used to evaluate the relationship between chemicals and biological activities of germinated rice. The PLS-DA score plot exhibited a noticeable separation between the three rice varieties into three clusters by PC1 and PC2. The PLS model indicated that α-linolenic acid, γ-oryzanol, α-tocopherol, γ-aminobutyric acid, 3-hydroxybutyric acid, fumaric acid, fatty acids, threonine, tryptophan, and vanillic acid were significantly correlated with the higher bioactivities demonstrated by GBR that was extracted in 100% ethanol. Subsequently, the proposed biosynthetic pathway analysis revealed that the increased quantities of secondary metabolites found in GBR may contribute to its nutritional value and health benefits. |
| first_indexed | 2025-11-15T11:59:46Z |
| format | Article |
| id | upm-74943 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:59:46Z |
| publishDate | 2018 |
| publisher | National Laboratories of Foods and Drugs |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-749432020-02-26T09:21:04Z http://psasir.upm.edu.my/id/eprint/74943/ Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study Pramai, Phaiwan Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, Maulidiani Abas, Faridah Jiamyangyuen, Sudarat In an attempt to profile the metabolites of three different varieties of germinated rice, specifically black (GBR), red, and white rice, a 1H-nuclear-magnetic-resonance-based metabolomics approach was conducted. Multivariate data analysis was applied to discriminate between the three different varieties using a partial least squares discriminant analysis (PLS-DA) model. The PLS model was used to evaluate the relationship between chemicals and biological activities of germinated rice. The PLS-DA score plot exhibited a noticeable separation between the three rice varieties into three clusters by PC1 and PC2. The PLS model indicated that α-linolenic acid, γ-oryzanol, α-tocopherol, γ-aminobutyric acid, 3-hydroxybutyric acid, fumaric acid, fatty acids, threonine, tryptophan, and vanillic acid were significantly correlated with the higher bioactivities demonstrated by GBR that was extracted in 100% ethanol. Subsequently, the proposed biosynthetic pathway analysis revealed that the increased quantities of secondary metabolites found in GBR may contribute to its nutritional value and health benefits. National Laboratories of Foods and Drugs 2018-01 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/74943/1/Metabolite.pdf Pramai, Phaiwan and Abdul Hamid, Nur Ashikin and Mediani, Ahmed and Maulidiani, Maulidiani and Abas, Faridah and Jiamyangyuen, Sudarat (2018) Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study. Journal of Food and Drug Analysis, 26 (1). 47 - 57. ISSN 1021-9498 10.1016/j.jfda.2016.11.023 |
| spellingShingle | Pramai, Phaiwan Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, Maulidiani Abas, Faridah Jiamyangyuen, Sudarat Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title | Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title_full | Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title_fullStr | Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title_full_unstemmed | Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title_short | Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| title_sort | metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study |
| url | http://psasir.upm.edu.my/id/eprint/74943/ http://psasir.upm.edu.my/id/eprint/74943/ http://psasir.upm.edu.my/id/eprint/74943/1/Metabolite.pdf |